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Home ยป Immunization of cattle with the MSP-1 surface protein complex induces protection against a structurally variant Anaplasma marginale isolate.

Immunization of cattle with the MSP-1 surface protein complex induces protection against a structurally variant Anaplasma marginale isolate.

TitleImmunization of cattle with the MSP-1 surface protein complex induces protection against a structurally variant Anaplasma marginale isolate.
Publication TypeJournal Article
Year of Publication1989
AuthorsPalmer, GH, Barbet, AF, Cantor, GH, McGuire, TC
JournalInfect Immun
Volume57
Issue11
Pagination3666-9
Date Published1989 Nov
ISSN0019-9567
KeywordsAnaplasma, Anaplasmosis, Animals, Antigens, Bacterial, Antigens, Surface, Bacterial Proteins, Cattle, Cattle Diseases, Molecular Weight, Species Specificity
Abstract

The Anaplasma marginale surface protein complex MSP-1 of the Florida isolate is composed of a 105-kilodalton (kDa) polypeptide, which bears a neutralization-sensitive epitope, and a 100-kDa polypeptide. Antigenically similar polypeptides in the Okanogan, Wash. (Washington-O), isolate MSP-1 are 86 and 100 kDa, respectively. Immunization of cattle with Florida isolate MSP-1 induced antibody titers to both MSP-1 polypeptides and protected cattle against homologous and heterologous challenge.
Alternate JournalInfect. Immun.
PubMed ID2807542
PubMed Central IDPMC259883