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CERID Bibliography
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Author Title Type [ Year] Filters: Keyword is Protein Binding [Clear All Filters]
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Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1. Bioorg Med Chem Lett. 2012 ;22(16):5264-7.
Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix α0. J Virol. 2012 ;86(6):3112-20.
. Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection. Structure. 2012 ;20(10):1681-91.
The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. Cell Host Microbe. 2012 ;11(5):528-37.
. CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 ;208(9):1741-7.
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice. J Med Chem. 2011 ;54(11):3935-49.
Screening a fragment cocktail library using ultrafiltration. Anal Bioanal Chem. 2011 ;401(5):1585-91.
Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature. 2011 ;479(7373):423-7.
. Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure-activity relationships with Trypanosoma brucei GSK-3. Mol Biochem Parasitol. 2011 ;176(2):98-108.
. Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 ;67(Pt 9):1078-83.
Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol. 2010 ;184(5):2677-85.
Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nat Struct Mol Biol. 2010 ;17(9):1088-95.
RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP. RNA. 2010 ;16(11):2108-19.
. Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery. J Med Chem. 2010 ;53(10):3887-98.
. Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents. J Med Chem. 2010 ;53(19):6867-88.
Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor. Virology. 2009 ;394(1):99-108.
. Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics. 2009 ;37(3):239-48.
. Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell. 2008 ;29(4):428-40.
. Protein geranylgeranyltransferase-I of Trypanosoma cruzi. Mol Biochem Parasitol. 2008 ;157(1):32-43.
. Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 ;64(Pt 6):474-8.
A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin. J Exp Med. 2007 ;204(2):393-403.
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