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CERID Bibliography

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2013
Page AV, Tarr PI, Watkins SL, Rajwans N, Petruzziello-Pellegrini TN, Marsden PA, Kain KC, W Liles C. Dysregulation of Angiopoietin 1 and 2 in Escherichia coli O157:H7 Infection and the Hemolytic-Uremic Syndrome. J Infect Dis. 2013 ;208(6):929-33.
Darwish I, Banner D, Mubareka S, Kim H, Besla R, Kelvin DJ, Kain KC, W Liles C. Mesenchymal stromal (stem) cell therapy fails to improve outcomes in experimental severe influenza. PLoS One. 2013 ;8(8):e71761.
Higgins SJ, Xing K, Kim H, Kain DC, Wang F, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Tracey KJ, Kain KC, et al. Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria. Malar J. 2013 ;12:105.
2012
Wolofsky KT, Ayi K, Branch DR, Hult AK, Olsson ML, W Liles C, Cserti-Gazdewich CM, Kain KC. ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes. PLoS Pathog. 2012 ;8(10):e1002942.
Darwish I, Miller C, Kain KC, W Liles C. Inhaled nitric oxide therapy fails to improve outcome in experimental severe influenza. Int J Med Sci. 2012 ;9(2):157-62.
2011
Ricciuto DR, Santos CC dos, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, Lafferty EI, Cook DJ, Fox-Robichaud A, Kahnamoui K, et al. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med. 2011 ;39(4):702-10.
Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, W Liles C, et al. Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. PLoS One. 2011 ;6(2):e17440.
Conroy AL, McDonald CR, Silver KL, W Liles C, Kain KC. Complement activation: a critical mediator of adverse fetal outcomes in placental malaria?. Trends Parasitol. 2011 ;27(7):294-9.
Kim H, Higgins S, W Liles C, Kain KC. Endothelial activation and dysregulation in malaria: a potential target for novel therapeutics. Curr Opin Hematol. 2011 ;18(3):177-85.
Higgins SJ, Kain KC, W Liles C. Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria. Expert Rev Anti Infect Ther. 2011 ;9(9):803-19.
Hawkes M, Opoka RO, Namasopo S, Miller C, Thorpe KE, Lavery JV, Conroy AL, W Liles C, John CC, Kain KC. Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial. Trials. 2011 ;12:176.
Serghides L, Kim H, Lu Z, Kain DC, Miller C, Francis RC, W Liles C, Zapol WM, Kain KC. Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria. PLoS One. 2011 ;6(11):e27714.
Hawkes M, Opoka ROpika, Namasopo S, Miller C, Conroy AL, Serghides L, Kim H, Thampi N, W Liles C, John CC, et al. Nitric oxide for the adjunctive treatment of severe malaria: hypothesis and rationale. Med Hypotheses. 2011 ;77(3):437-44.
Conroy AL, W Liles C, Molyneux ME, Rogerson SJ, Kain KC. Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi. PLoS One. 2011 ;6(12):e28540.
Finney CAm, Hawkes CA, Kain DC, Dhabangi A, Musoke C, Cserti-Gazdewich C, Oravecz T, W Liles C, Kain KC. S1P is associated with protection in human and experimental cerebral malaria. Mol Med. 2011 ;17(7-8):717-25.
Page AV, Kotb M, McGeer A, Low DE, Kain KC, W Liles C. Systemic dysregulation of angiopoietin-1/2 in streptococcal toxic shock syndrome. Clin Infect Dis. 2011 ;52(8):e157-61.
2010
Hawkes M, Li X, Crockett M, Diassiti A, Finney C, Min-Oo G, W Liles C, Liu J, Kain KC. CD36 deficiency attenuates experimental mycobacterial infection. BMC Infect Dis. 2010 ;10:299.
Finney CAM, Lu Z, Hawkes M, Yeh W-C, W Liles C, Kain KC. Divergent roles of IRAK4-mediated innate immune responses in two experimental models of severe malaria. Am J Trop Med Hyg. 2010 ;83(1):69-74.
Wang F, Lu Z, Hawkes M, Yang H, Kain KC, W Liles C. Fas (CD95) induces rapid, TLR4/IRAK4-dependent release of pro-inflammatory HMGB1 from macrophages. J Inflamm (Lond). 2010 ;7:30.
Hawkes M, Li X, Crockett M, Diassiti A, W Liles C, Liu J, Kain KC. Malaria exacerbates experimental mycobacterial infection in vitro and in vivo. Microbes Infect. 2010 ;12(11):864-74.
2009
Ayi K, W Liles C, Gros P, Kain KC. Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. J Infect Dis. 2009 ;200(8):1289-99.
Conroy A, Serghides L, Finney C, Owino SO, Kumar S, D Gowda C, W Liles C, Moore JM, Kain KC. C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. PLoS One. 2009 ;4(3):e4953.
Serghides L, Patel SN, Ayi K, Lu Z, D Gowda C, W Liles C, Kain KC. Rosiglitazone modulates the innate immune response to Plasmodium falciparum infection and improves outcome in experimental cerebral malaria. J Infect Dis. 2009 ;199(10):1536-45.
Lovegrove FE, Tangpukdee N, Opoka RO, Lafferty EI, Rajwans N, Hawkes M, Krudsood S, Looareesuwan S, John CC, W Liles C, et al. Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One. 2009 ;4(3):e4912.
Helmers AJ, D Gowda C, Kain KC, W Liles C. Statins fail to improve outcome in experimental cerebral malaria and potentiate Toll-like receptor-mediated cytokine production by murine macrophages. Am J Trop Med Hyg. 2009 ;81(4):631-7.

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