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CERID Bibliography

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Author Title [ Type(Desc)] Year
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Journal Article
Hawn TR, Berrington WR, Smith IA, Uematsu S, Akira S, Aderem A, Smith KD, Skerrett SJ. Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila. J Immunol. 2007 ;179(10):6981-7.
Randhawa AKaur, Shey MS, Keyser A, Peixoto B, Wells RD, de Kock M, Lerumo L, Hughes J, Hussey G, Hawkridge A, et al. Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants. PLoS Pathog. 2011 ;7(8):e1002174.
Sapkota BR, Macdonald M, Berrington WR, E Misch A, Ranjit C, M Siddiqui R, Kaplan G, Hawn TR. Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes. Hum Immunol. 2010 ;71(10):992-8.
Hawn TR, Verbon A, Lettinga KD, Zhao LPing, Li SSue, Laws RJ, Skerrett SJ, Beutler B, Schroeder L, Nachman A, et al. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med. 2003 ;198(10):1563-72.
Hawn TR, E Misch A, Dunstan SJ, Thwaites GE, Lan NTN, Quy HT, Chau TTH, Rodrigues S, Nachman A, Janer M, et al. A common human TLR1 polymorphism regulates the innate immune response to lipopeptides. Eur J Immunol. 2007 ;37(8):2280-9.
Horne DJ, Randhawa AK, Chau TTH, Bang ND, Yen NTB, Farrar JJ, Dunstan SJ, Hawn TR. Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis. J Infect Dis. 2012 ;205(4):586-94.
Bochud P-Y, Hawn TR, Aderem A. Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. J Immunol. 2003 ;170(7):3451-4.
Andersen-Nissen E, Hawn TR, Smith KD, Nachman A, Lampano AE, Uematsu S, Akira S, Aderem A. Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. J Immunol. 2007 ;178(8):4717-20.
D O'Mahony S, Pham U, Iyer R, Hawn TR, W Liles C. Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages. Int J Med Sci. 2008 ;5(1):1-8.
Marr KA, S Balajee A, Hawn TR, Ozinsky A, Pham U, Akira S, Aderem A, W Liles C. Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. Infect Immun. 2003 ;71(9):5280-6.
Scholes D, Hawn TR, Roberts PL, Li SS, Stapleton AE, Zhao L-P, Stamm WE, Hooton TM. Family history and risk of recurrent cystitis and pyelonephritis in women. J Urol. 2010 ;184(2):564-9.
Wurfel MM, Hawn TR. Genetic variants associated with susceptibility to Helicobacter pylori. JAMA. 2013 ;310(9):976.
Baker AR, Qiu F, Randhawa AKaur, Horne DJ, Adams MD, Shey M, Barnholtz-Sloan J, Mayanja-Kizza H, Kaplan G, Hanekom WA, et al. Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data. PLoS One. 2012 ;7(10):e47597.
Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LPing, Hooton TM. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS One. 2009 ;4(12):e8300.
Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TTH, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 2012 ;148(3):434-46.
Dunstan SJ, Hawn TR, Hue NThi, Parry CP, Ho VAn, Vinh H, Diep TSong, House D, Wain J, Aderem A, et al. Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam. J Infect Dis. 2005 ;191(7):1068-71.
Seshadri C, Shenoy M, Wells RD, Hensley-McBain T, Andersen-Nissen E, McElrath JM, Cheng T-Y, D Moody B, Hawn TR. Human CD1a deficiency is common and genetically regulated. J Immunol. 2013 ;191(4):1586-93.
Berrington WR, Hawn TR. Human susceptibility to legionnaires' disease. Methods Mol Biol. 2013 ;954:541-51.
Misch EA, Macdonald M, Ranjit C, Sapkota BR, Wells RD, M Siddiqui R, Kaplan G, Hawn TR. Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. PLoS Negl Trop Dis. 2008 ;2(5):e231.
Shah JA, Vary JC, Chau TTH, Bang ND, Yen NTB, Farrar JJ, Dunstan SJ, Hawn TR. Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis. J Immunol. 2012 ;189(4):1737-46.
Hawn TR, Ozinsky A, Williams LM, Rodrigues S, Clark A, Pham U, Hill HR, Ochs H, Aderem A, W Liles C. Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes. Hum Immunol. 2005 ;66(7):842-7.
Thuong NThuy Thuon, Dunstan SJ, Chau TThi Hong, Thorsson V, Simmons CP, Quyen NThan Ha, Thwaites GE, Lan NThi Ngoc, Hibberd M, Teo YY, et al. Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles. PLoS Pathog. 2008 ;4(12):e1000229.
T West E, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Myers ND, Emond MJ, Wurfel MM, Hawn TR, Peacock SJ, et al. Impaired TLR5 functionality is associated with survival in melioidosis. J Immunol. 2013 ;190(7):3373-9.
Caws M, Thwaites G, Dunstan S, Hawn TR, Lan NThi Ngoc, Thuong NThuy Thuon, Stepniewska K, Huyen MNguyet Thu, Bang NDuc, Loc THuu, et al. The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog. 2008 ;4(3):e1000034.
Hawn TR, Ozinsky A, Underhill DM, Buckner FS, Akira S, Aderem A. Leishmania major activates IL-1 alpha expression in macrophages through a MyD88-dependent pathway. Microbes Infect. 2002 ;4(8):763-71.

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