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A tollgate for typhoid.

TitleA tollgate for typhoid.
Publication TypeJournal Article
Year of Publication2012
AuthorsFang, FC, Bäumler, AJ
JournalCell
Volume151
Issue3
Pagination473-5
Date Published2012 Oct 26
ISSN1097-4172
Abstract

Humans are uniquely susceptible to typhoid fever caused by infection with Salmonella enterica serovar Typhi. Mathur et al. now report that mice lacking Toll-like receptor 11, which is absent in humans, can be lethally infected with S. Typhi, a breakthrough that promises to speed the development of better vaccines.

DOI10.1016/j.cell.2012.10.016
Alternate JournalCell
PubMed ID23101620
Grant ListAI44170 / AI / NIAID NIH HHS / United States
AI76246 / AI / NIAID NIH HHS / United States
AI90882 / AI / NIAID NIH HHS / United States
AI91966 / AI / NIAID NIH HHS / United States