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Home ยป Opsonization of Anaplasma marginale mediated by bovine antibody against surface protein MSP-1.

Opsonization of Anaplasma marginale mediated by bovine antibody against surface protein MSP-1.

TitleOpsonization of Anaplasma marginale mediated by bovine antibody against surface protein MSP-1.
Publication TypeJournal Article
Year of Publication1993
AuthorsCantor, GH, Pontzer, CH, Palmer, GH
JournalVet Immunol Immunopathol
Volume37
Issue3-4
Pagination343-50
Date Published1993 Aug
ISSN0165-2427
KeywordsAnaplasma, Anaplasmosis, Animals, Antibodies, Bacterial, Antigens, Surface, Cattle, Cells, Cultured, Macrophages, Merozoite Surface Protein 1, Opsonin Proteins, Phagocytosis, Protein Precursors, Protozoan Proteins
Abstract

Antibody from cattle immunized with purified major surface protein-1 (MSP-1) was demonstrated to significantly enhance phagocytosis of Florida strain Anaplasma marginale by bovine macrophages in vitro. Serum immunoglobulin from individual MSP-1 immunized, protected cattle varied in ability to promote phagocytosis, however all sera were significantly opsonic as compared with sera from sham immunized control cattle.
Alternate JournalVet. Immunol. Immunopathol.
PubMed ID8236809