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Home ยป Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates.

Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates.

TitleMultiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates.
Publication TypeJournal Article
Year of Publication2000
AuthorsCenturion-Lara, A, Sun, ES, Barrett, LK, Castro, C, Lukehart, SA, Van Voorhis, WC
JournalJ Bacteriol
Volume182
Issue8
Pagination2332-5
Date Published2000 Apr
ISSN0021-9193
KeywordsAlleles, Amino Acid Sequence, Antibodies, Bacterial, Bacterial Outer Membrane Proteins, Gene Duplication, Genes, Bacterial, Humans, Molecular Sequence Data, Sequence Homology, Amino Acid, Syphilis, Treponema pallidum
Abstract

Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolates and 7 of 8 non-pallidum isolates, and tprD3 is found in one T. pallidum subsp. pertenue isolate. Antibodies against TprD2 are found in persons with syphilis, demonstrating that tprD2 is expressed during infection.
Alternate JournalJ. Bacteriol.
PubMed ID10735882