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Home ยป Identification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera.

Identification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera.

TitleIdentification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera.
Publication TypeJournal Article
Year of Publication1988
AuthorsMcElwain, TF, Palmer, GH, Goff, WL, McGuire, TC
JournalInfect Immun
Volume56
Issue6
Pagination1658-60
Date Published1988 Jun
ISSN0019-9567
KeywordsAnimals, Antibodies, Bacterial, Antigen-Antibody Reactions, Antigens, Protozoan, Babesia, Babesiosis, Cattle, Cattle Diseases, Epitopes, Species Specificity
Abstract

Immunoprecipitation of radiolabeled antigens with bovine antisera indicated that many Babesia bigemina and Babesia bovis merozoite proteins contain isolate-common epitopes, while at least 16 B. bigemina and 8 B. bovis proteins contain species-cross-reactive epitopes. One immunogenic, isolate-common, and species-specific candidate diagnostic protein from each species was identified.
Alternate JournalInfect. Immun.
PubMed ID2453470
PubMed Central IDPMC259453
Grant ListAI-07025 / AI / NIAID NIH HHS / United States
GM-07853 / GM / NIGMS NIH HHS / United States