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Heat shock protein 60 is the major antigen which stimulates delayed-type hypersensitivity reaction in the macaque model of Chlamydia trachomatis salpingitis.

TitleHeat shock protein 60 is the major antigen which stimulates delayed-type hypersensitivity reaction in the macaque model of Chlamydia trachomatis salpingitis.
Publication TypeJournal Article
Year of Publication2004
AuthorsLichtenwalner, AB, Patton, DL, Van Voorhis, WC, Sweeney, YCT, Kuo, C-C
JournalInfect Immun
Volume72
Issue2
Pagination1159-61
Date Published2004 Feb
ISSN0019-9567
KeywordsAnimals, Chaperonin 60, Chlamydia Infections, Chlamydia trachomatis, Female, Hypersensitivity, Delayed, Lymphocytes, Macaca nemestrina, Salpingitis
Abstract

Chlamydial delayed-type hypersensitivity antigens were analyzed by using the subcutaneous salpingeal autotransplant model of Macaca nemestrina infected with Chlamydia trachomatis serovar E. Heat shock protein 60 was the only antigen shown to induce delayed-type hypersensitivity among other antigens tested, including UV-inactivated organisms, recombinant major outer membrane protein, purified outer membrane proteins, and heat shock protein 10.

Alternate JournalInfect. Immun.
PubMed ID14742566