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Growth-phase regulation of plasmid virulence genes in Salmonella.

TitleGrowth-phase regulation of plasmid virulence genes in Salmonella.
Publication TypeJournal Article
Year of Publication1995
AuthorsGuiney, DG, Libby, S, Fang, FC, Krause, M, Fierer, J
JournalTrends Microbiol
Volume3
Issue7
Pagination275-9
Date Published1995 Jul
ISSN0966-842X
KeywordsAnimals, Gene Expression Regulation, Bacterial, Humans, Plasmids, Salmonella, Virulence
Abstract

Virulence genes in the genus Salmonella are regulated by growth phase and by environmental signals, which allows a sequential program of expression during infection. Conditions that promote the expression of loci required in systemic infection, including the plasmid-encoded spv genes, are the opposite of the factors that induce genes involved in the invasion of epithelial cells in the gastrointestinal tract.
Alternate JournalTrends Microbiol.
PubMed ID7551642
Grant ListAI32178 / AI / NIAID NIH HHS / United States
DK35108 / DK / NIDDK NIH HHS / United States