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Fighting the flu with inflammasome signaling.

TitleFighting the flu with inflammasome signaling.
Publication TypeJournal Article
Year of Publication2009
AuthorsOwen, DM, Gale, M
JournalImmunity
Volume30
Issue4
Pagination476-8
Date Published2009 Apr 17
ISSN1097-4180
KeywordsAnimals, Carrier Proteins, Humans, Influenza A virus, Monocytes, Neutrophils, Signal Transduction
Abstract

A wide variety of stimuli induce the inflammasome, but little is known about its role in immune protection against viruses. In this issue of Immunity, Allen et al. (2009) and Thomas et al. (2009) describe a critical role for NLRP3 induction of the inflammasome and protection against influenza virus infection.
DOI10.1016/j.immuni.2009.03.011
Alternate JournalImmunity
PubMed ID19371712