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Efficacy of aztreonam in treatment of experimental syphilis in rabbits.
| Title | Efficacy of aztreonam in treatment of experimental syphilis in rabbits. |
| Publication Type | Journal Article |
| Year of Publication | 1984 |
| Authors | Lukehart, SA, Baker-Zander, SA, Holmes, KK |
| Journal | Antimicrob Agents Chemother |
| Volume | 25 |
| Issue | 3 |
| Pagination | 390-1 |
| Date Published | 1984 Mar |
| ISSN | 0066-4804 |
| Keywords | Animals, Anti-Bacterial Agents, Aztreonam, Male, Penicillin G Benzathine, Rabbits, Syphilis, Treponema pallidum |
| Abstract | The efficacy of aztreonam (SQ 26,776) in the therapy of active syphilis infection was evaluated in the rabbit model. Aztreonam was effective in treating active syphilis at a dose of 25 mg/kg given intramuscularly twice daily for 10 days; doses of 2.5 and 0.25 mg/kg were not effective. |
| Alternate Journal | Antimicrob. Agents Chemother. |
| PubMed ID | 6372685 |
| PubMed Central ID | PMC185528 |
