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Home ยป Characterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.

Characterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.

TitleCharacterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.
Publication TypeJournal Article
Year of Publication2006
AuthorsZhuang, Y, Mwangi, W, Brown, WC, Davis, WC, Hope, JC, Palmer, GH
JournalClin Vaccine Immunol
Volume13
Issue9
Pagination1064-9
Date Published2006 Sep
ISSN1556-6811
KeywordsAnimals, Antibodies, Monoclonal, Antigen-Presenting Cells, Antigens, CD13, Cattle, Cell Culture Techniques, Cell Separation, Cells, Cultured, Dendritic Cells, Histocompatibility Antigens Class II, Immunoglobulin Isotypes, Male, Phenotype, Spleen
Abstract

Immature dendritic cells (DCs) resident in bovine spleens represent a distinct CD11a(+) CD11c(+) CD13(+) CD172(+) CD205(+) population compared to those circulating in peripheral blood or trafficking via afferent lymph. Upon cytokine-induced maturation, splenic DCs both efficiently present antigen in the stimulation of allogeneic lymphocyte proliferation and recall antigen-specific responses.
DOI10.1128/CVI.00178-06
Alternate JournalClin. Vaccine Immunol.
PubMed ID16960120
PubMed Central IDPMC1563577
Grant ListR01 AI44005 / AI / NIAID NIH HHS / United States
T32 AI07025 / AI / NIAID NIH HHS / United States