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Barking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis.

TitleBarking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis.
Publication TypeJournal Article
Year of Publication2002
AuthorsO'Regan, AW, Castro, C, Lukehart, SA, Kasznica, JM, Rice, PA, Joyce-Brady, MF
JournalThorax
Volume57
Issue10
Pagination917-8
Date Published2002 Oct
ISSN0040-6376
KeywordsAged, Aortitis, Diagnostic Errors, Female, Humans, Magnetic Resonance Angiography, Polymerase Chain Reaction, Syphilis, Cardiovascular
Abstract

The presentation of syphilitic aortitis is often atypical and available serological tests are non-specific. The diagnostic gold standard remains direct identification of microorganisms in tissue. We present a case of syphilitic aortitis that presented as a mediastinal mass and report the use of polymerase chain reaction for Treponema pallidum to diagnose syphilitic aortic disease.

Alternate JournalThorax
PubMed ID12324682
PubMed Central IDPMC1746207