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Home ยป Analysis of the Anaplasma marginale major surface protein 1 complex protein composition by tandem mass spectrometry.

Analysis of the Anaplasma marginale major surface protein 1 complex protein composition by tandem mass spectrometry.

TitleAnalysis of the Anaplasma marginale major surface protein 1 complex protein composition by tandem mass spectrometry.
Publication TypeJournal Article
Year of Publication2006
AuthorsMacmillan, H, Brayton, KA, Palmer, GH, McGuire, TC, Munske, G, Siems, WF, Brown, WC
JournalJ Bacteriol
Volume188
Issue13
Pagination4983-91
Date Published2006 Jul
ISSN0021-9193
KeywordsAmino Acid Sequence, Anaplasma marginale, Anaplasmosis, Animals, Bacterial Outer Membrane Proteins, Base Sequence, Cattle, Chromatography, Liquid, Genes, Bacterial, Mass Spectrometry, Molecular Sequence Data, Multigene Family
Abstract

The protective major surface protein 1 (MSP1) complex of Anaplasma marginale is a heteromer of MSP1a and MSP1b, encoded by a multigene family. The msp1beta sequences were highly conserved throughout infection. However, liquid chromatography-tandem mass spectrometry analysis identified only a single MSP1b protein, MSP1b1, within the MSP1 complex.
DOI10.1128/JB.00170-06
Alternate JournalJ. Bacteriol.
PubMed ID16788207
PubMed Central IDPMC1483013
Grant ListAI053692 / AI / NIAID NIH HHS / United States