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CERID Bibliography

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Author Title [ Type(Desc)] Year
Filters: Keyword is Polymorphism, Single Nucleotide and Author is Hawn, Thomas R  [Clear All Filters]
Journal Article
Hawn TR, Verbon A, Lettinga KD, Zhao LPing, Li SSue, Laws RJ, Skerrett SJ, Beutler B, Schroeder L, Nachman A, et al. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med. 2003 ;198(10):1563-72.
Hawn TR, E Misch A, Dunstan SJ, Thwaites GE, Lan NTN, Quy HT, Chau TTH, Rodrigues S, Nachman A, Janer M, et al. A common human TLR1 polymorphism regulates the innate immune response to lipopeptides. Eur J Immunol. 2007 ;37(8):2280-9.
Horne DJ, Randhawa AK, Chau TTH, Bang ND, Yen NTB, Farrar JJ, Dunstan SJ, Hawn TR. Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis. J Infect Dis. 2012 ;205(4):586-94.
Bochud P-Y, Hawn TR, Aderem A. Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. J Immunol. 2003 ;170(7):3451-4.
Baker AR, Qiu F, Randhawa AKaur, Horne DJ, Adams MD, Shey M, Barnholtz-Sloan J, Mayanja-Kizza H, Kaplan G, Hanekom WA, et al. Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data. PLoS One. 2012 ;7(10):e47597.
Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LPing, Hooton TM. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS One. 2009 ;4(12):e8300.
Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TTH, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 2012 ;148(3):434-46.
Berrington WR, Hawn TR. Human susceptibility to legionnaires' disease. Methods Mol Biol. 2013 ;954:541-51.
Misch EA, Macdonald M, Ranjit C, Sapkota BR, Wells RD, M Siddiqui R, Kaplan G, Hawn TR. Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. PLoS Negl Trop Dis. 2008 ;2(5):e231.
Shah JA, Vary JC, Chau TTH, Bang ND, Yen NTB, Farrar JJ, Dunstan SJ, Hawn TR. Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis. J Immunol. 2012 ;189(4):1737-46.
Thuong NThuy Thuon, Dunstan SJ, Chau TThi Hong, Thorsson V, Simmons CP, Quyen NThan Ha, Thwaites GE, Lan NThi Ngoc, Hibberd M, Teo YY, et al. Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles. PLoS Pathog. 2008 ;4(12):e1000229.
Caws M, Thwaites G, Dunstan S, Hawn TR, Lan NThi Ngoc, Thuong NThuy Thuon, Stepniewska K, Huyen MNguyet Thu, Bang NDuc, Loc THuu, et al. The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog. 2008 ;4(3):e1000034.
Hawn TR, Wu H, Grossman JM, Hahn BH, Tsao BP, Aderem A. A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2005 ;102(30):10593-7.
Bochud P-Y, Hawn TR, M Siddiqui R, Saunderson P, Britton S, Abraham I, Argaw ATadesse, Janer M, Zhao LPing, Kaplan G, et al. Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy. J Infect Dis. 2008 ;197(2):253-61.
Hawn TR, Verbon A, Janer M, Zhao LPing, Beutler B, Aderem A. Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci U S A. 2005 ;102(7):2487-9.