You are here

Nichole R. Klatt, Ph.D.

Department of Pharmaceutics | University of Washington | WaNPRC | 3018 Western Avenue Seattle, WA 98121-1023
(206) 221-0254

Lab Staff

Tiffany Henlsey-McBain (graduate student, Molecular and Cellular Biology)
Ryan Cheu (graduate student, pharmaceutics)
Alex Zevin (postdoc)
Jen Manuzak (postdoc)
Nichole R. Klatt, Ph.D.
Assistant Professor, Department of Pharmaceutics, School of Pharmacy, University of Washington | Core Scientist, Washington National Primate Research Center (WaNPRC), University of Washington

The Klatt research lab specifically focuses on understanding mechanisms underlying mucosal immune dysfunction and alterations in the microbiome during HIV infection, and developing novel therapeutic interventions to treat HIV disease pathogenesis and reservoir, and prevent HIV acquisition.

The complex interactions between the epithelial barrier, the microbiome, mucus and immune cells are critical for protection from disease. The focus of my lab is to understand mechanisms underlying mucosal dysfunction, microbiome dysbiosis and altered immunity in mucosal tissues (mainly gastrointestinal and female reproductive tracts), and how these defects contribute to HIV transmission and pathogenesis. Our ultimate goal is to improve prevention and treatment strategies for HIV infection.

Associated Research: