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Edward A. Clark, Ph.D.

Office: 
750 Republican Street, E343 Seattle, WA 98109
Phone: 
(206) 543-8706

Lab Staff

Kevin Draves
Geraldine Shu
Daniela Giordano, PhD
Lucy Young, PhD
Kelsey Roe, PhD
Zachary Zalinger, PhD
Jessica Cooper
Edward A. Clark, Ph.D.
CIIID Associate Director | Transgenic Mouse Core Leader | Professor, Microbiology and Immunology | Adjunct Professor, Medicine (Rheumatology) | Member, Immune Mechanisms of Flavivirus Control Center

Research in The Clark laboratory is focused on investigating how the innate immune system programs protective antibody responses to infectious diseases and also contributes to the development of autoantibodies in diseases such as systemic lupus erythematosus (SLE). The Clark group is examining the role of cytokines such as B cell activating factor (BAFF) and type I interferon in protective humoral immunity and autoimmunity. The lab also is developing vaccines containing viral antigens attached to engineered monoclonal antibodies that program protective immune responses against viruses such as hepatitis B virus and West Nile virus. The lab works closely with OnTarget Vaccines, a new Seattle-based company to develop therapeutic vaccines.

Associated Cores: