Title: Biblio RTF Export
Author: Biblio 7.x

Darling AM, McDonald CR, Conroy AL, Hayford KT, Liles CW, Wang M, Aboud S, Urassa WS, Kain KC, Fawzi WW. Angiogenic and inflammatory biomarkers in midpregnancy and small-for-gestational-age outcomes in Tanzania. Am J Obstet Gynecol. 2014  .

Giacani L, Iverson-Cabral SL, King JCK, Molini BJ, Lukehart SA, Centurion-Lara A. Complete Genome Sequence of the Treponema pallidum subsp. pallidum Sea81-4 Strain. Genome Announc. 2014  ;2(2).

Cameron CE, Lukehart SA. Current status of syphilis vaccine development: need, challenges, prospects. Vaccine. 2014  ;32(14):1602-9.

Lal M, Zhu C, McClurkan C, Koelle DM, Miller P, Afonso C, Donadeu M, Dungu B, Chen D. Development of a low-dose fast-dissolving tablet formulation of Newcastle disease vaccine for low-cost backyard poultry immunisation. Vet Rec. 2014  ;174(20):504.

Husain S, Resende MR, Rajwans N, Zamel R, Pilewski JM, Crespo MM, Singer LG, McCurry KR, Kolls JK, Keshavjee S, et al. Elevated CXCL10 (IP-10) in bronchoalveolar lavage fluid is associated with acute cellular rejection after human lung transplantation. Transplantation. 2014  ;97(1):90-7.

Giacani L, Lukehart SA. The endemic treponematoses. Clin Microbiol Rev. 2014  ;27(1):89-115.

Liles CW, Kain KC. Endothelial Activation and Dysfunction in the Pathogenesis of Microvascular Obstruction in Severe Malaria--A Viable Target for Therapeutic Adjunctive Intervention. J Infect Dis. 2014  .

Murphy SC, Hermsen CC, Douglas AD, Edwards NJ, Petersen I, Fahle GA, Adams M, Berry AA, Billman ZP, Gilbert SC, et al. External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance. PLoS One. 2014  ;9(5):e97398.

López-Yglesias AH, Zhao X, Quarles EK, Lai MA, VandenBos T, Strong RK, Smith KD. Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway. J Immunol. 2014  ;192(4):1587-96.

Kim H, Erdman LK, Lu Z, Serghides L, Zhong K, Dhabangi A, Musoke C, Gerard C, Cserti-Gazdewich C, Liles CW, et al. Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria. Infect Immun. 2014  ;82(1):371-9.

Conroy AL, Gélvez M, Hawkes M, Rajwans N, Liles CW, Villar-Centeno LA, Kain KC. Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study. BMC Infect Dis. 2014  ;14:35.

Morrison LJ, Lorens E, Bandiera G, Liles CW, Lee L, Hyland R, Mcdonald-Blumer H, Allard JP, Panisko DM, Heathcote JE, et al. Impact of a formal mentoring program on academic promotion of Department of Medicine faculty: A comparative study. Med Teach. 2014  ;36(7):608-14.

Liles CW, Matthay MA, Dos Santos CC, Weiss DJ, Stewart DJ. Mesenchymal stromal (stem) cell therapy: an emerging immunomodulatory strategy for the adjunctive treatment of sepsis. Am J Respir Crit Care Med. 2014  ;189(3):363-4.

Kim H, Darwish I, Monroy M-F, Prockop DJ, Liles CW, Kain KC. Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome. BMC Immunol. 2014  ;15:1.

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Liles CW, John CC, Kain KC. Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda. Am J Trop Med Hyg. 2014  ;90(4):605-8.

Chapuis AG, Afanasiev OK, Iyer JG, Paulson KG, Parvathaneni U, Hwang JH, Lai I, Roberts IM, Sloan HL, Bhatia S, et al. Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I. Cancer Immunol Res. 2014  ;2(1):27-36.

Aplin AC, Ligresti G, Fogel E, Zorzi P, Smith K, Nicosia RF. Regulation of angiogenesis, mural cell recruitment and adventitial macrophage behavior by Toll-like receptors. Angiogenesis. 2014  ;17(1):147-61.

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Liles CW, John CC, Kain KC. Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children. Malar J. 2014  ;13:43.

Johnston C, Zhu J, Jing L, Laing KJ, McClurkan CM, Klock A, Diem K, Jin L, Stanaway J, Tronstein E, et al. Virologic and immunologic evidence of multifocal genital herpes simplex virus 2 infection. J Virol. 2014  ;88(9):4921-31.

Johnson JR, Tchesnokova V, Johnston B, Clabots C, Roberts PL, Billig M, Riddell K, Rogers P, Qin X, Butler-Wu S, et al. Abrupt emergence of a single dominant multidrug-resistant strain of Escherichia coli. J Infect Dis. 2013  ;207(6):919-28.

Rubinow KB, Wall VZ, Nelson J, Mar D, Bomsztyk K, Askari B, Lai MA, Smith KD, Han MSook, Vivekanandan-Giri A, et al. Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages. J Biol Chem. 2013  ;288(14):9957-70.

Wollish AC, Ferris MT, Blevins LK, Loo Y-M, Gale M, Heise MT. An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo. Virology. 2013  ;435(2):269-80.

Page AV, W Liles C. Biomarkers of endothelial activation/dysfunction in infectious diseases. Virulence. 2013  ;4(6):507-16.

Ekouevi DK, Balestre E, Coffie PA, Minta D, Messou E, Sawadogo A, Minga A, Sow PSalif, Bissagnene E, Eholie SP, et al. Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study. PLoS One. 2013  ;8(6):e66135.

Dittrich T, Macor L, Gervaldo M, Fungo F, Otero L, Lin CY, Chi LC, Fang FC, Lii SW, Wong KT, et al. Charge separation in donor-acceptor spiro compounds at metal and metal oxide surfaces investigated by surface photovoltage. J Nanosci Nanotechnol. 2013  ;13(7):5158-63.

Graham SM, Mwilu R, W Liles C. Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: A systematic review. Virulence. 2013  ;4(6):564-71.

Weiss DJ, Bates JHt, Gilbert T, W Liles C, Lutzko C, Rajagopal J, Prockop DJ. Conference Report: Stem Cells and Cell Therapies in Lung Biology and Diseases University of Vermont, July 2011. Ann Am Thorac Soc. 2013  .

Jacob ST, Pavlinac PB, Nakiyingi L, Banura P, Baeten JM, Morgan K, Magaret A, Manabe Y, Reynolds SJ, W Liles C, et al. Correction: Mycobacterium tuberculosis Bacteremia in a Cohort of HIV-Infected Patients Hospitalized with Severe Sepsis in Uganda-High Frequency, Low Clinical Suspicion and Derivation of a Clinical Prediction Score. PLoS One. 2013  ;8(8).

Suryadevara PK, Racherla KK, Olepu S, Norcross NR, Tatipaka HB, Arif JA, Planer JD, Lepesheva GI, Verlinde CLMJ, Buckner FS, et al. Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14?-demethylase as anti-Chagas disease agents. Bioorg Med Chem Lett. 2013  ;23(23):6492-9.

Lloyd JK, Duchin JS, Borchert J, Quintana HFlores, Robertson A. Diarrhetic shellfish poisoning, Washington, USA, 2011. Emerg Infect Dis. 2013  ;19(8):1314-6.

Page AV, Tarr PI, Watkins SL, Rajwans N, Petruzziello-Pellegrini TN, Marsden PA, Kain KC, W Liles C. Dysregulation of Angiopoietin 1 and 2 in Escherichia coli O157:H7 Infection and the Hemolytic-Uremic Syndrome. J Infect Dis. 2013  ;208(6):929-33.

Kodali V, Littke MH, Tilton SC, Teeguarden JG, Shi L, Frevert CW, Wang W, Pounds JG, Thrall BD. Dysregulation of macrophage activation profiles by engineered nanoparticles. ACS Nano. 2013  ;7(8):6997-7010.

Darwish I, W Liles C. Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction. Virulence. 2013  ;4(6):572-82.

Graham SM, Rajwans N, Jaoko W, Estambale BBA, R McClelland S, Overbaugh J, W Liles C. Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression. AIDS. 2013  ;27(11):1803-13.

Page AV, W Liles C. Enterohemorrhagic Escherichia coli Infections and the Hemolytic-Uremic Syndrome. Med Clin North Am. 2013  ;97(4):681-95, xi.

Stigi K, Baer A, Duchin JS, Lofy K. Evaluation of Electronic Ambulatory Care Data for Influenza-Like Illness Surveillance, Washington State. J Public Health Manag Pract. 2013  .

Centurion-Lara A, Giacani L, Godornes C, Molini BJ, Brinck Reid T, Lukehart SA. Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains. PLoS Negl Trop Dis. 2013  ;7(5):e2222.

Woodland A, Grimaldi R, Luksch T, Cleghorn LAT, Ojo KK, Van Voorhis WC, Brenk R, Frearson JA, Gilbert IH, Wyatt PG. From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules. ChemMedChem. 2013  ;8(7):1127-37.

Stone AEL, Giugliano S, Schnell G, Cheng L, Leahy KF, Golden-Mason L, Gale M, Rosen HR. Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells. PLoS Pathog. 2013  ;9(4):e1003316.

Wilkins C, Woodward J, Lau DT-Y, Barnes A, Joyce M, McFarlane N, McKeating JA, D Tyrrell L, Gale M. IFITM1 is a tight junction protein that inhibits hepatitis C virus entry. Hepatology. 2013  ;57(2):461-9.

T West E, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Myers ND, Emond MJ, Wurfel MM, Hawn TR, Peacock SJ, et al. Impaired TLR5 functionality is associated with survival in melioidosis. J Immunol. 2013  ;190(7):3373-9.

Lai Y, Altemeier WA, Vandree J, Piliponsky AM, Johnson B, Appel CL, Frevert CW, Hyde DM, Ziegler SF, Smith DE, et al. Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33. J Allergy Clin Immunol. 2013  .

Lai MA, Quarles EK, López-Yglesias AH, Zhao X, Hajjar AM, Smith KD. Innate immune detection of flagellin positively and negatively regulates salmonella infection. PLoS One. 2013  ;8(8):e72047.

Lau DT-Y, Negash A, Chen J, Crochet N, Sinha M, Zhang Y, Guedj J, Holder S, Saito T, Lemon SM, et al. Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection. Gastroenterology. 2013  ;144(2):402-413.e12.

Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, Vick SC, Clepper L, Thackray L, Brassil MM, Virgin HW, et al. IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog. 2013  ;9(1):e1003118.

Seshadri C, Turner MT, Lewinsohn DM, D Moody B, Van Rhijn I. Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis. J Immunol. 2013  ;190(1):278-84.

Darwish I, Banner D, Mubareka S, Kim H, Besla R, Kelvin DJ, Kain KC, W Liles C. Mesenchymal stromal (stem) cell therapy fails to improve outcomes in experimental severe influenza. PLoS One. 2013  ;8(8):e71761.

Jacob ST, Pavlinac PB, Nakiyingi L, Banura P, Baeten JM, Morgan K, Magaret A, Manabe Y, Reynolds SJ, W Liles C, et al. Mycobacterium tuberculosis Bacteremia in a Cohort of HIV-Infected Patients Hospitalized with Severe Sepsis in Uganda-High Frequency, Low Clinical Sand Derivation of a Clinical Prediction Score. PLoS One. 2013  ;8(8):e70305.

Nairz M, Schleicher U, Schroll A, Sonnweber T, Theurl I, Ludwiczek S, Talasz H, Brandacher G, Moser PL, Muckenthaler MU, et al. Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J Exp Med. 2013  ;210(5):855-73.

Dutton JL, Li B, Woo W-P, Marshak JO, Xu Y, Huang M-L, Dong L, Frazer IH, Koelle DM. A Novel DNA Vaccine Technology Conveying Protection against a Lethal Herpes Simplex Viral Challenge in Mice. PLoS One. 2013  ;8(10):e76407.

Lazear HM, Pinto AK, Ramos HJ, Vick SC, Shrestha B, Suthar MS, Gale M, Diamond MS. Pattern Recognition Receptor MDA5 Modulates CD8+ T Cell-Dependent Clearance of West Nile Virus from the Central Nervous System. J Virol. 2013  ;87(21):11401-11415.

Tchesnokova V, Billig M, Chattopadhyay S, Linardopoulou E, Aprikian P, Roberts PL, Skrivankova V, Johnston B, Gileva A, Igusheva I, et al. Predictive diagnostics for Escherichia coli infections based on the clonal association of antimicrobial resistance and clinical outcome. J Clin Microbiol. 2013  ;51(9):2991-9.

Deriu E, Liu JZ, Pezeshki M, Edwards RA, Ochoa RJ, Contreras H, Libby SJ, Fang FC, Raffatellu M. Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron. Cell Host Microbe. 2013  ;14(1):26-37.

Graham SM, Rajwans N, Tapia KA, Jaoko W, Estambale BBa, R McClelland S, Overbaugh J, W Liles C. A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy. BMC Infect Dis. 2013  ;13(1):263.

Hallstrand TS, Lai Y, Altemeier WA, Appel CL, Johnson B, Frevert CW, Hudkins KL, Bollinger JG, Woodruff PG, Hyde DM, et al. Regulation and function of epithelial secreted phospholipase A2 group X in asthma. Am J Respir Crit Care Med. 2013  ;188(1):42-50.

Brown DE, Libby SJ, Moreland SM, McCoy MW, Brabb T, Stepanek A, Fang FC, Detweiler CS. Salmonella enterica causes more severe inflammatory disease in C57/BL6 Nramp1G169 mice than Sv129S6 mice. Vet Pathol. 2013  ;50(5):867-76.

Li J, Ding SC, Cho H, Chung BC, Gale M, Chanda SK, Diamond MS. A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response. MBio. 2013  ;4(3):e00385-13.

W Liles C. Special focus: Endothelial activation/dysfunction. Virulence. 2013  ;4(6):504-6.

Ojo KK, Eastman RT, Vidadala R, Zhang Z, Rivas KL, Choi R, Lutz JD, Reid MC, Fox AMW, Hulverson MA, et al. A specific inhibitor of PfCDPK4 blocks malaria transmission: Chemical-genetic validation. J Infect Dis. 2013  .

Higgins SJ, Xing K, Kim H, Kain DC, Wang F, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Tracey KJ, Kain KC, et al. Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria. Malar J. 2013  ;12:105.

Ouwendijk WJ, Laing KJ, Verjans GM, Koelle DM. T-cell immunity to human alphaherpesviruses. Curr Opin Virol. 2013  ;3(4):452-60.

Salit IE, W Liles C, Smith C. Tularemia endocarditis from domestic pet exposure. Am J Med. 2013  ;126(10):e1.

Moreira CG, Herrera CM, Needham BD, Parker CT, Libby SJ, Fang FC, M Trent S, Sperandio V. Virulence and stress-related periplasmic protein (VisP) in bacterial/host associations. Proc Natl Acad Sci U S A. 2013  ;110(4):1470-5.

Wolofsky KT, Ayi K, Branch DR, Hult AK, Olsson ML, W Liles C, Cserti-Gazdewich CM, Kain KC. ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes. PLoS Pathog. 2012  ;8(10):e1002942.

W Liles C. Is angiopoietin-2 the key piece in the sepsis puzzle?*. Crit Care Med. 2012  ;40(11):3100-1.

Gall A, Treuting P, Elkon KB, Loo Y-M, Gale M, Barber GN, Stetson DB. Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity. 2012  ;36(1):120-31.

Zhang Z, Ojo KK, Johnson SM, Larson ET, He P, Geiger JA, Castellanos-Gonzalez A, White CA, Parsons M, Merritt EA, et al. Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1. Bioorg Med Chem Lett. 2012  ;22(16):5264-7.

Kong R, Li H, Bibollet-Ruche F, Decker JM, Zheng NN, Gottlieb GS, Kiviat NB, Sow PSalif, Georgiev I, Hahn BH, et al. Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection. J Virol. 2012  ;86(2):947-60.

Palmer LM, Schulz JM, Murphy SC, Ledergerber D, Murayama M, Larkum ME. The cellular basis of GABA(B)-mediated interhemispheric inhibition. Science. 2012  ;335(6071):989-93.

Caballero MC, Pedroni MJ, Palmer GH, Suarez CE, Davitt C, Lau AOT. Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast. Mol Biochem Parasitol. 2012  ;181(2):125-33.

Xing K, Murthy S, W Liles C, Singh JM. Clinical utility of biomarkers of endothelial activation in sepsis--a systematic review. Crit Care. 2012  ;16(1):R7.

Giacani L, Brandt SL, Puray-Chavez M, Reid TBrinck, Godornes C, Molini BJ, Benzler M, Hartig JS, Lukehart SA, Centurion-Lara A. Comparative investigation of the genomic regions involved in antigenic variation of the TprK antigen among treponemal species, subspecies, and strains. J Bacteriol. 2012  ;194(16):4208-25.

Patel MR, Loo Y-M, Horner SM, Gale M, Malik HS. Convergent evolution of escape from hepaciviral antagonism in primates. PLoS Biol. 2012  ;10(3):e1001282.

Jing L, Haas J, Chong TM, Bruckner JJ, Dann GC, Dong L, Marshak JO, McClurkan CL, Yamamoto TN, Bailer SM, et al. Cross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine. J Clin Invest. 2012  ;122(2):654-73.

Petruzziello-Pellegrini TN, Yuen DA, Page AV, Patel S, Soltyk AM, Matouk CC, Wong DK, Turgeon PJ, Fish JE, Ho JJDavid, et al. The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest. 2012  ;122(2):759-76.

Johnson SM, Murphy RC, Geiger JA, DeRocher AE, Zhang Z, Ojo KK, Larson ET, Perera GBK, Dale EJ, He P, et al. Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity. J Med Chem. 2012  ;55(5):2416-26.

Koh CY, Kim JE, Shibata S, Ranade RM, Yu M, Liu J, Gillespie RJ, Buckner FS, Verlinde CLMJ, Fan E, et al. Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection. Structure. 2012  ;20(10):1681-91.

Thuong NTT, Hawn TR, Chau TTH, Bang ND, Yen NTB, Thwaites GE, Teo YY, Seielstad M, Hibberd M, Lan NTN, et al. Epiregulin (EREG) variation is associated with susceptibility to tuberculosis. Genes Immun. 2012  ;13(3):275-81.

Kisiela DI, Chattopadhyay S, Libby SJ, Karlinsey JE, Fang FC, Tchesnokova V, Kramer JJ, Beskhlebnaya V, Samadpour M, Grzymajlo K, et al. Evolution of Salmonella enterica virulence via point mutations in the fimbrial adhesin. PLoS Pathog. 2012  ;8(6):e1002733.

Giacani L, Chattopadhyay S, Centurion-Lara A, Jeffrey BM, Le HT, Molini BJ, Lukehart SA, Sokurenko EV, Rockey DD. Footprint of positive selection in Treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen. PLoS Negl Trop Dis. 2012  ;6(6):e1698.

MacMullin G, Mackenzie R, Lau R, Khang J, Zhang H, Rajwans N, W Liles C, Pillai DR. Host immune response in returning travellers infected with malaria. Malar J. 2012  ;11:148.

Ramos HJ, Lanteri MC, Blahnik G, Negash A, Suthar MS, Brassil MM, Sodhi K, Treuting PM, Busch MP, Norris PJ, et al. IL-1? signaling promotes CNS-intrinsic immune control of West Nile virus infection. PLoS Pathog. 2012  ;8(11):e1003039.

Laing KJ, Dong L, Sidney J, Sette A, Koelle DM. Immunology in the Clinic Review Series; focus on host responses: T cell responses to herpes simplex viruses. Clin Exp Immunol. 2012  ;167(1):47-58.

Darwish I, Miller C, Kain KC, W Liles C. Inhaled nitric oxide therapy fails to improve outcome in experimental severe influenza. Int J Med Sci. 2012  ;9(2):157-62.

Rudd PA, Wilson J, Gardner J, Larcher T, Babarit C, Le TT, Anraku I, Kumagai Y, Loo Y-M, Gale M, et al. Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. J Virol. 2012  ;86(18):9888-98.

Bedard KM, Wang ML, Proll SC, Loo Y-M, Katze MG, Gale M, Iadonato SP. Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses. J Virol. 2012  ;86(13):7334-44.

A Bruce G, Bielefeldt-Ohmann H, Barcy S, Bakke AM, Lewis P, Tsai C-C, Murnane RD, Rose TM. Macaque homologs of EBV and KSHV show uniquely different associations with simian AIDS-related lymphomas. PLoS Pathog. 2012  ;8(10):e1002962.

Levin-Edens E, Soge OO, No D, Stiffarm A, J Meschke S, Roberts MC. Methicillin-resistant Staphylococcus aureus from Northwest marine and freshwater recreational beaches. FEMS Microbiol Ecol. 2012  ;79(2):412-20.

Liu HMinyi, Loo Y-M, Horner SM, Zornetzer GA, Katze MG, Gale M. The mitochondrial targeting chaperone 14-3-3? regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. Cell Host Microbe. 2012  ;11(5):528-37.

Larson ET, Ojo KK, Murphy RC, Johnson SM, Zhang Z, Kim JE, Leibly DJ, Fox AMW, Reid MC, Dale EJ, et al. Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1. J Med Chem. 2012  ;55(6):2803-10.

Santos CC dos, Murthy S, Hu P, Shan Y, Haitsma JJ, Mei SHJ, Stewart DJ, W Liles C. Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis. Am J Pathol. 2012  ;181(5):1681-92.

Moss NJ, Magaret A, Laing KJ, Kask AS, Wang M, Mark KE, Schiffer JT, Wald A, Koelle DM. Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes. J Virol. 2012  ;86(18):9952-63.

Buckner FS, Bahia MTerezinha, Suryadevara PK, White KL, Shackleford DM, Chennamaneni NKumar, Hulverson MA, Laydbak JU, Chatelain E, Scandale I, et al. Pharmacological characterization, structural studies, and in vivo activities of anti-Chagas disease lead compounds derived from tipifarnib. Antimicrob Agents Chemother. 2012  ;56(9):4914-21.

Fritsche G, Nairz M, Libby SJ, Fang FC, Weiss G. Slc11a1 (Nramp1) impairs growth of Salmonella enterica serovar typhimurium in macrophages via stimulation of lipocalin-2 expression. J Leukoc Biol. 2012  ;92(2):353-9.

Leibly DJ, Nguyen TN, Kao LT, Hewitt SN, Barrett LK, Van Voorhis WC. Stabilizing additives added during cell lysis aid in the solubilization of recombinant proteins. PLoS One. 2012  ;7(12):e52482.

Larson ET, Kim JE, Napuli AJ, Verlinde CLMJ, Fan E, Zucker FH, Van Voorhis WC, Buckner FS, Hol WGJ, Merritt EA. Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia. Acta Crystallogr D Biol Crystallogr. 2012  ;68(Pt 9):1194-200.

Polyak SJ, Morishima C, Scott JD, Gastaminza P, Cox A, de Araújo EStanislau, Higgs MR, Loo Y-M, Golden-Mason L, Lindenbach BD, et al. A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology. 2012  ;142(1):e1-5.

Lee H-C, Headley MB, Loo Y-M, Berlin A, Gale M, Debley JS, Lukacs NW, Ziegler SF. Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection. J Allergy Clin Immunol. 2012  ;130(5):1187-1196.e5.

West TE, Chierakul W, Chantratita N, Limmathurotsakul D, Wuthiekanun V, Emond MJ, Hawn TR, Peacock SJ, Skerrett SJ. Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis. Genes Immun. 2012  ;13(1):38-46.

Ojo KK, Pfander C, Mueller NR, Burstroem C, Larson ET, Bryan CM, Fox AMW, Reid MC, Johnson SM, Murphy RC, et al. Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors. J Clin Invest. 2012  ;122(6):2301-5.

Grimes M, Sahi SK, B Godornes C, Tantalo LC, Roberts N, Bostick D, Marra CM, Lukehart SA. Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington. Sex Transm Dis. 2012  ;39(12):954-8.

Shibata S, Gillespie RJ, Ranade RM, Koh CY, Kim JE, Laydbak JU, Zucker FH, Hol WGJ, Verlinde CLMJ, Buckner FS, et al. Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization. J Med Chem. 2012  ;55(14):6342-51.

Schnell G, Loo Y-M, Marcotrigiano J, Gale M. Uridine composition of the poly-U/UC tract of HCV RNA defines non-self recognition by RIG-I. PLoS Pathog. 2012  ;8(8):e1002839.

Herbeck JT, Müller V, Maust BS, Ledergerber B, Torti C, Di Giambenedetto S, Gras L, Günthard HF, Jacobson LP, Mullins JI, et al. Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission. AIDS. 2012  ;26(2):193-205.

Ricciuto DR, Santos CC dos, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, Lafferty EI, Cook DJ, Fox-Robichaud A, Kahnamoui K, et al. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med. 2011  ;39(4):702-10.

Lewis DA, Lukehart SA. Antimicrobial resistance in Neisseria gonorrhoeae and Treponema pallidum: evolution, therapeutic challenges and the need to strengthen global surveillance. Sex Transm Infect. 2011  ;87 Suppl 2:ii39-43.

Randhawa AKaur, Shey MS, Keyser A, Peixoto B, Wells RD, de Kock M, Lerumo L, Hughes J, Hussey G, Hawkridge A, et al. Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants. PLoS Pathog. 2011  ;7(8):e1002174.

Lau AOt, Kalyanaraman A, Echaide I, Palmer GH, Bock R, Pedroni MJ, Rameshkumar M, Ferreira MB, Fletcher TI, McElwain TF. Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level. BMC Genomics. 2011  ;12:410.

Lazear HM, Pinto AK, Vogt MR, Gale M, Diamond MS. Beta interferon controls West Nile virus infection and pathogenesis in mice. J Virol. 2011  ;85(14):7186-94.

Kasmar AG, Van Rhijn I, Cheng T-Y, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, et al. CD1b tetramers bind ?? T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011  ;208(9):1741-7.

Luke JM, Simon GG, Söderholm J, Errett JS, J August T, Gale M, Hodgson CP, Williams JA. Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine. J Virol. 2011  ;85(3):1370-83.

Page AV, W Liles C. Colony-stimulating factors in the prevention and management of infectious diseases. Infect Dis Clin North Am. 2011  ;25(4):803-17.

Juergens RA, Wrangle J, Vendetti FP, Murphy SC, Zhao M, Coleman B, Sebree R, Rodgers K, Hooker CM, Franco N, et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov. 2011  ;1(7):598-607.

Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, W Liles C, et al. Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. PLoS One. 2011  ;6(2):e17440.

Leeper T, Zhang S, Van Voorhis WC, Myler PJ, Varani G. Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1141-7.

Conroy AL, McDonald CR, Silver KL, W Liles C, Kain KC. Complement activation: a critical mediator of adverse fetal outcomes in placental malaria?. Trends Parasitol. 2011  ;27(7):294-9.

Larson ET, Kim JE, Castaneda LJ, Napuli AJ, Zhang Z, Fan E, Zucker FH, Verlinde CLMJ, Buckner FS, Van Voorhis WC, et al. The double-length tyrosyl-tRNA synthetase from the eukaryote Leishmania major forms an intrinsically asymmetric pseudo-dimer. J Mol Biol. 2011  ;409(2):159-76.

Sugimoto JD, Borse NN, Ta ML, Stockman LJ, Fischer GE, Yang Y, M Halloran E, Longini IM, Duchin JS. The effect of age on transmission of 2009 pandemic influenza A (H1N1) in a camp and associated households. Epidemiology. 2011  ;22(2):180-7.

Kim H, Higgins S, W Liles C, Kain KC. Endothelial activation and dysregulation in malaria: a potential target for novel therapeutics. Curr Opin Hematol. 2011  ;18(3):177-85.

Lee WL, W Liles C. Endothelial activation, dysfunction and permeability during severe infections. Curr Opin Hematol. 2011  ;18(3):191-6.

Reed DL, Currier RW, Walton SF, Conrad M, Sullivan SA, Carlton JM, Read TD, Severini A, Tyler S, Eberle R, et al. The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms. Ann N Y Acad Sci. 2011  ;1230:74-107.

Mesplet M, Palmer GH, Pedroni MJ, Echaide I, Florin-Christensen M, Schnittger L, Lau AOT. Genome-wide analysis of peptidase content and expression in a virulent and attenuated Babesia bovis strain pair. Mol Biochem Parasitol. 2011  ;179(2):111-3.

R de Claro A, Zhu X, Tang J, Morgan-Stevenson V, Schwartz BR, Iwata A, W Liles C, Raines EW, Harlan JM. Hematopoietic Fas deficiency does not affect experimental atherosclerotic lesion formation despite inducing a proatherogenic state. Am J Pathol. 2011  ;178(6):2931-7.

Bryan CM, Bhandari J, Napuli AJ, Leibly DJ, Choi R, Kelley A, Van Voorhis WC, Edwards TE, Stewart LJ. High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1010-4.

Harman AN, Lai J, Turville S, Samarajiwa S, Gray L, Marsden V, Mercier SK, Mercier S, Jones K, Nasr N, et al. HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production. Blood. 2011  ;118(2):298-308.

Gottlieb GS, Smith RA, Badiane NMery Dia, Ba S, Hawes SE, Toure M, Starling AK, Traore F, Sall F, Cherne SL, et al. HIV-2 integrase variation in integrase inhibitor-naïve adults in Senegal, West Africa. PLoS One. 2011  ;6(7):e22204.

Agnes JT, Brayton KA, LaFollett M, Norimine J, Brown WC, Palmer GH. Identification of Anaplasma marginale outer membrane protein antigens conserved between A. marginale sensu stricto strains and the live A. marginale subsp. centrale vaccine. Infect Immun. 2011  ;79(3):1311-8.

Crowther GJ, Napuli AJ, Gilligan JH, Gagaring K, Borboa R, Francek C, Chen Z, Dagostino EF, Stockmyer JB, Wang Y, et al. Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. Mol Biochem Parasitol. 2011  ;175(1):21-9.

Loo Y-M, Gale M. Immune signaling by RIG-I-like receptors. Immunity. 2011  ;34(5):680-92.

Darwish I, Mubareka S, W Liles C. Immunomodulatory therapy for severe influenza. Expert Rev Anti Infect Ther. 2011  ;9(7):807-22.

Higgins SJ, Kain KC, W Liles C. Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria. Expert Rev Anti Infect Ther. 2011  ;9(9):803-19.

Quakkelaar ED, Redeker A, Haddad EK, Harari A, McCaughey SM, Duhen T, Filali-Mouhim A, Goulet J-P, Loof NM, Ossendorp F, et al. Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One. 2011  ;6(2):e16819.

Hawkes M, Opoka RO, Namasopo S, Miller C, Thorpe KE, Lavery JV, Conroy AL, W Liles C, John CC, Kain KC. Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial. Trials. 2011  ;12:176.

Serghides L, Kim H, Lu Z, Kain DC, Miller C, Francis RC, W Liles C, Zapol WM, Kain KC. Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria. PLoS One. 2011  ;6(11):e27714.

Brien JD, Daffis S, Lazear HM, Cho H, Suthar MS, Gale M, Diamond MS. Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection. PLoS Pathog. 2011  ;7(9):e1002230.

Iyer JG, Afanasiev OK, McClurkan C, Paulson K, Nagase K, Jing L, Marshak JO, Dong L, Carter J, Lai I, et al. Merkel cell polyomavirus-specific CD8? and CD4? T-cell responses identified in Merkel cell carcinomas and blood. Clin Cancer Res. 2011  ;17(21):6671-80.

Roberts MC, Soge OO, Horst JA, Ly KA, Milgrom P. Methicillin-resistant Staphylococcus aureus from dental school clinic surfaces and students. Am J Infect Control. 2011  ;39(8):628-32.

Horner SM, Liu HMinyi, Park HSoo, Briley J, Gale M. Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc Natl Acad Sci U S A. 2011  ;108(35):14590-5.

Richardson AR, Payne EC, Younger N, Karlinsey JE, Thomas VC, Becker LA, Navarre WW, Castor ME, Libby SJ, Fang FC. Multiple targets of nitric oxide in the tricarboxylic acid cycle of Salmonella enterica serovar typhimurium. Cell Host Microbe. 2011  ;10(1):33-43.

Giordano D, Li C, Suthar MS, Draves KE, Ma DY, Gale M, Clark EA. Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses. J Leukoc Biol. 2011  ;89(3):443-55.

Hawkes M, Opoka ROpika, Namasopo S, Miller C, Conroy AL, Serghides L, Kim H, Thampi N, W Liles C, John CC, et al. Nitric oxide for the adjunctive treatment of severe malaria: hypothesis and rationale. Med Hypotheses. 2011  ;77(3):437-44.

Tsunooka N, Hirayama S, Medin JA, W Liles C, Keshavjee S, Waddell TK. A novel tissue-engineered approach to problems of the postpneumonectomy space. Ann Thorac Surg. 2011  ;91(3):880-6.

Bunce PE, High SM, Nadjafi M, Stanley K, W Liles C, Christian MD. Pandemic H1N1 influenza infection and vascular thrombosis. Clin Infect Dis. 2011  ;52(2):e14-7.

Conroy AL, W Liles C, Molyneux ME, Rogerson SJ, Kain KC. Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi. PLoS One. 2011  ;6(12):e28540.

Elahi S, Dinges WL, Lejarcegui N, Laing KJ, Collier AC, Koelle DM, McElrath JM, Horton H. Protective HIV-specific CD8+ T cells evade Treg cell suppression. Nat Med. 2011  ;17(8):989-95.

Levin-Edens E, Meschke JScott, Roberts MC. Quantification of methicillin-resistant Staphylococcus aureus strains in marine and freshwater samples by the most-probable-number method. Appl Environ Microbiol. 2011  ;77(10):3541-3.

Dileepan T, Linehan JL, Moon JJ, Pepper M, Jenkins MK, Cleary PP. Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection. PLoS Pathog. 2011  ;7(9):e1002252.

Finney CAm, Hawkes CA, Kain DC, Dhabangi A, Musoke C, Cserti-Gazdewich C, Oravecz T, W Liles C, Kain KC. S1P is associated with protection in human and experimental cerebral malaria. Mol Med. 2011  ;17(7-8):717-25.

Wald A, Koelle DM, Fife K, Warren T, Leclair K, Chicz RM, Monks S, Levey DL, Musselli C, Srivastava PK. Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons. Vaccine. 2011  ;29(47):8520-9.

Shibata S, Gillespie RJ, Kelley AM, Napuli AJ, Zhang Z, Kovzun KV, Pefley RM, Lam J, Zucker FH, Van Voorhis WC, et al. Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice. Antimicrob Agents Chemother. 2011  ;55(5):1982-9.

Edwards TE, Abramov AB, Smith ER, Baydo RO, Leonard JT, Leibly DJ, Thompkins KB, Clifton MC, Gardberg AS, Staker BL, et al. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. BMC Struct Biol. 2011  ;11:39.

Buchko GW, Edwards TE, Abendroth J, Arakaki TL, Law L, Napuli AJ, Hewitt SN, Van Voorhis WC, Stewart LJ, Staker BL, et al. Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1078-83.

Larson ET, Kim JE, Zucker FH, Kelley A, Mueller N, Napuli AJ, Verlinde CLMJ, Fan E, Buckner FS, Van Voorhis WC, et al. Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate. Biochimie. 2011  ;93(3):570-82.

Clifton MC, Abendroth J, Edwards TE, Leibly DJ, Gillespie AK, Ferrell M, Dieterich SH, Exley I, Staker BL, Myler PJ, et al. Structure of the cystathionine ?-synthase MetB from Mycobacterium ulcerans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1154-8.

Leibly DJ, Abendroth J, Bryan CM, Sankaran B, Kelley A, Barrett LK, Stewart L, Van Voorhis WC. Structure of thymidylate kinase from Ehrlichia chaffeensis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1090-4.

Nguyen TN, Abendroth J, Leibly DJ, Le KP, Guo W, Kelley A, Stewart L, Myler PJ, Van Voorhis WC. Structure of triosephosphate isomerase from Cryptosporidium parvum. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1095-9.

Edwards TE, Bryan CM, Leibly DJ, Dieterich SH, Abendroth J, Sankaran B, Sivam D, Staker BL, Van Voorhis WC, Myler PJ, et al. Structures of a putative ?-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1038-43.

Edwards TE, Leibly DJ, Bhandari J, Statnekov JB, Phan I, Dieterich SH, Abendroth J, Staker BL, Van Voorhis WC, Myler PJ, et al. Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1032-7.

Levin-Edens E, Bonilla N, J Meschke S, Roberts MC. Survival of environmental and clinical strains of methicillin-resistant Staphylococcus aureus [MRSA] in marine and fresh waters. Water Res. 2011  ;45(17):5681-6.

Ho EL, Lukehart SA. Syphilis: using modern approaches to understand an old disease. J Clin Invest. 2011  ;121(12):4584-92.

Page AV, Kotb M, McGeer A, Low DE, Kain KC, W Liles C. Systemic dysregulation of angiopoietin-1/2 in streptococcal toxic shock syndrome. Clin Infect Dis. 2011  ;52(8):e157-61.

Paulson KG, Iyer JG, Tegeder AR, Thibodeau R, Schelter J, Koba S, Schrama D, Simonson WT, Lemos BD, Byrd DR, et al. Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J Clin Oncol. 2011  ;29(12):1539-46.

Baer A, Elbert Y, Burkom HS, Holtry R, Lombardo JS, Duchin JS. Usefulness of syndromic data sources for investigating morbidity resulting from a severe weather event. Disaster Med Public Health Prep. 2011  ;5(1):37-45.

Liu HMinyi, Gale M. ZAPS electrifies RIG-I signaling. Nat Immunol. 2011  ;12(1):11-2.

Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin T-Y, Schneller S, Zust R, Dong H, et al. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature. 2010  ;468(7322):452-6.

Giacani L, Molini BJ, Kim EY, B Godornes C, B Leader T, Tantalo LC, Centurion-Lara A, Lukehart SA. Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis. J Immunol. 2010  ;184(7):3822-9.

Hawkes M, Li X, Crockett M, Diassiti A, Finney C, Min-Oo G, W Liles C, Liu J, Kain KC. CD36 deficiency attenuates experimental mycobacterial infection. BMC Infect Dis. 2010  ;10:299.

Guiguemde AW, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, et al. Chemical genetics of Plasmodium falciparum. Nature. 2010  ;465(7296):311-5.

Gessain A, Rose TM, Lavergne A, Lacoste V. Comment on Mugisha et al. J Med Primatol 2010; 39: 71-76. J Med Primatol. 2010  ;39(5):363-4; author reply 365-6.

Giacani L, Jeffrey BM, Molini BJ, Le HT, Lukehart SA, Centurion-Lara A, Rockey DD. Complete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain. J Bacteriol. 2010  ;192(10):2645-6.

Larson ET, Mudeppa DG, Gillespie RJ, Mueller N, Napuli AJ, Arif JA, Ross J, Arakaki TL, Lauricella A, Detitta G, et al. The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase. J Mol Biol. 2010  ;396(5):1244-59.

Merritt EA, Arakaki TL, Larson ET, Kelley A, Mueller N, Napuli AJ, Zhang L, Deditta G, Luft J, Verlinde CLMJ, et al. Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica. Mol Biochem Parasitol. 2010  ;169(2):95-100.

Merritt EA, Arakaki TL, Gillespie RJ, Larson ET, Kelley A, Mueller N, Napuli AJ, Kim J, Zhang L, Verlinde CLMJ, et al. Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs. J Mol Biol. 2010  ;397(2):481-94.

Marra CM, Tantalo LC, Sahi SK, Maxwell CL, Lukehart SA. CXCL13 as a cerebrospinal fluid marker for neurosyphilis in HIV-infected patients with syphilis. Sex Transm Dis. 2010  ;37(5):283-7.

Boggild AK, Nicks BA, Yen L, Van Voorhis W, McMullen R, Buckner FS, W Liles C. Delusional parasitosis: six-year experience with 23 consecutive cases at an academic medical center. Int J Infect Dis. 2010  ;14(4):e317-21.

Pepper M, Linehan JL, Pagán AJ, Zell T, Dileepan T, P Cleary P, Jenkins MK. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nat Immunol. 2010  ;11(1):83-9.

Murphy RC, Ojo KK, Larson ET, Castellanos-Gonzalez A, Perera GBK, Keyloun KR, Kim JE, Bhandari JG, Muller NR, Verlinde CLMJ, et al. Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. ACS Med Chem Lett. 2010  ;1(7):331-335.

Finney CAM, Lu Z, Hawkes M, Yeh W-C, W Liles C, Kain KC. Divergent roles of IRAK4-mediated innate immune responses in two experimental models of severe malaria. Am J Trop Med Hyg. 2010  ;83(1):69-74.

Laing KJ, Magaret AS, Mueller DE, Zhao L, Johnston C, De Rosa SC, Koelle DM, Wald A, Corey L. Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes. J Clin Immunol. 2010  ;30(5):703-22.

Traag BA, Driks A, Stragier P, Bitter W, Broussard G, Hatfull G, Chu F, Adams KN, Ramakrishnan L, Losick R. Do mycobacteria produce endospores?. Proc Natl Acad Sci U S A. 2010  ;107(2):878-81.

Marra CM, Sahi SK, Tantalo LC, Godornes C, Reid T, Behets F, Rompalo A, Klausner JD, Yin YPing, Mulcahy F, et al. Enhanced molecular typing of treponema pallidum: geographical distribution of strain types and association with neurosyphilis. J Infect Dis. 2010  ;202(9):1380-8.

Morris AM, Stewart TE, Shandling M, McIntaggart S, W Liles C. Establishing an antimicrobial stewardship program. Healthc Q. 2010  ;13(2):64-70.

Larson AM, Fung AM, Fang FC. Evaluation of tcdB real-time PCR in a three-step diagnostic algorithm for detection of toxigenic Clostridium difficile. J Clin Microbiol. 2010  ;48(1):124-30.

Yuan HJ, Jain M, Snow KK, Gale M, Lee WM. Evolution of hepatitis C virus NS5A region in breakthrough patients during pegylated interferon and ribavirin therapy*. J Viral Hepat. 2010  ;17(3):208-16.

Scholes D, Hawn TR, Roberts PL, Li SS, Stapleton AE, Zhao L-P, Stamm WE, Hooton TM. Family history and risk of recurrent cystitis and pyelonephritis in women. J Urol. 2010  ;184(2):564-9.

Wang F, Lu Z, Hawkes M, Yang H, Kain KC, W Liles C. Fas (CD95) induces rapid, TLR4/IRAK4-dependent release of pro-inflammatory HMGB1 from macrophages. J Inflamm (Lond). 2010  ;7:30.

Lau AOT, Cereceres K, Palmer GH, Fretwell DL, Pedroni MJ, Mosqueda J, McElwain TF. Genotypic diversity of merozoite surface antigen 1 of Babesia bovis within an endemic population. Mol Biochem Parasitol. 2010  ;172(2):107-12.

Curlin ME, Zioni R, Hawes SE, Liu Y, Deng W, Gottlieb GS, Zhu T, Mullins JI. HIV-1 envelope subregion length variation during disease progression. PLoS Pathog. 2010  ;6(12):e1001228.

Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, et al. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010  ;107(35):15589-94.

Suthar MS, Ma DY, Thomas S, Lund JM, Zhang N, Daffis S, Rudensky AY, Bevan MJ, Clark EA, Kaja M-K, et al. IPS-1 is essential for the control of West Nile virus infection and immunity. PLoS Pathog. 2010  ;6(2):e1000757.

Hawkes M, Li X, Crockett M, Diassiti A, W Liles C, Liu J, Kain KC. Malaria exacerbates experimental mycobacterial infection in vitro and in vivo. Microbes Infect. 2010  ;12(11):864-74.

Chun CD, W Liles C, Frevert CW, Glenny RW, Altemeier WA. Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study. BMC Pulm Med. 2010  ;10:57.

Mei SHJ, Haitsma JJ, Santos CC dos, Deng Y, Lai PFH, Slutsky AS, W Liles C, Stewart DJ. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med. 2010  ;182(8):1047-57.

Limou S, Coulonges C, Herbeck JT, van Manen D, An P, Le Clerc S, Delaneau O, Diop G, Taing L, Montes M, et al. Multiple-cohort genetic association study reveals CXCR6 as a new chemokine receptor involved in long-term nonprogression to AIDS. J Infect Dis. 2010  ;202(6):908-15.

Zucker FH, Stewart C, Delarosa J, Kim J, Zhang L, Xiao L, Ross J, Napuli AJ, Mueller N, Castaneda LJ, et al. Prediction of protein crystallization outcome using a hybrid method. J Struct Biol. 2010  ;171(1):64-73.

Dong L, Li P, Oenema T, McClurkan CL, Koelle DM. Public TCR use by herpes simplex virus-2-specific human CD8 CTLs. J Immunol. 2010  ;184(6):3063-71.

Burnside K, Lembo A, Reyes Mde Los, Iliuk A, Binhtran N-T, Connelly JE, Lin W-J, Schmidt BZ, Richardson AR, Fang FC, et al. Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphatase. PLoS One. 2010  ;5(6):e11071.

Edwards TE, Phan I, Abendroth J, Dieterich SH, Masoudi A, Guo W, Hewitt SN, Kelley A, Leibly D, Brittnacher MJ, et al. Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. PLoS One. 2010  ;5(9).

Ojo KK, Larson ET, Keyloun KR, Castaneda LJ, DeRocher AE, Inampudi KK, Kim JE, Arakaki TL, Murphy RC, Zhang L, et al. Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat Struct Mol Biol. 2010  ;17(5):602-7.

Watson-Jones D, Wald A, Celum C, Lingappa J, Weiss HA, Changalucha J, Baisley K, Tanton C, Hayes RJ, Marshak JO, et al. Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials. J Clin Microbiol. 2010  ;48(10):3496-503.

Crowther GJ, He P, Rodenbough PP, Thomas AP, Kovzun KV, Leibly DJ, Bhandari J, Castaneda LJ, Hol WGJ, Gelb MH, et al. Use of thermal melt curves to assess the quality of enzyme preparations. Anal Biochem. 2010  ;399(2):268-75.

Khare S, Alali W, Zhang S, Hunter D, Pugh R, Fang FC, Libby SJ, L Adams G. Vaccination with attenuated Salmonella enterica Dublin expressing E coli O157:H7 outer membrane protein Intimin induces transient reduction of fecal shedding of E coli O157:H7 in cattle. BMC Vet Res. 2010  ;6:35.

Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, Seifert M, Crouch M-LV, Hantke K, Akira S, et al. Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. Blood. 2009  ;114(17):3642-51.

Lanford RE, Evans MJ, Lohmann V, Lindenbach B, Gale M, Rehermann B, Chang K-M, Lemon SM. The accelerating pace of HCV research: a summary of the 15th International Symposium on Hepatitis C Virus And Related Viruses. Gastroenterology. 2009  ;136(1):9-16.

Ayi K, W Liles C, Gros P, Kain KC. Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. J Infect Dis. 2009  ;200(8):1289-99.

Richardson AR, Soliven KC, Castor ME, Barnes PD, Libby SJ, Fang FC. The Base Excision Repair system of Salmonella enterica serovar typhimurium counteracts DNA damage by host nitric oxide. PLoS Pathog. 2009  ;5(5):e1000451.

Webb-Robertson B-JM, McCue LAnn, Beagley N, McDermott JE, Wunschel DS, Varnum SM, Hu JZhi, Isern NG, Buchko GW, Mcateer K, et al. A Bayesian integration model of high-throughput proteomics and metabolomics data for improved early detection of microbial infections. Pac Symp Biocomput. 2009  :451-63.

Wilson EH, Harris TH, Mrass P, John B, Tait ED, Wu GF, Pepper M, E Wherry J, Dzierzinski F, Roos D, et al. Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers. Immunity. 2009  ;30(2):300-11.

Crowther GJ, Napuli AJ, Thomas AP, Chung DJ, Kovzun KV, Leibly DJ, Castaneda LJ, Bhandari J, Damman CJ, Hui R, et al. Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands. J Biomol Screen. 2009  ;14(6):700-7.

Conroy A, Serghides L, Finney C, Owino SO, Kumar S, D Gowda C, W Liles C, Moore JM, Kain KC. C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. PLoS One. 2009  ;4(3):e4953.

Kieran N, Wang X, Perkins J, Davis C, Kendrick E, Bakthavatsalam R, Dunbar N, Warner P, Nelson K, Smith KD, et al. Combination of peritubular c4d and transplant glomerulopathy predicts late renal allograft failure. J Am Soc Nephrol. 2009  ;20(10):2260-8.

Deitsch KW, Lukehart SA, Stringer JR. Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens. Nat Rev Microbiol. 2009  ;7(7):493-503.

Boggild AK, Page AV, Keystone JS, Morris AM, W Liles C. Delay in diagnosis: malaria in a returning traveller. CMAJ. 2009  ;180(11):1129-31.

Verlinde CLMJ, Fan E, Shibata S, Zhang Z, Sun Z, Deng W, Ross J, Kim J, Xiao L, Arakaki TL, et al. Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium. Curr Top Med Chem. 2009  ;9(18):1678-87.

Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LPing, Hooton TM. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS One. 2009  ;4(12):e8300.

Muller WJ, Dong L, Vilalta A, Byrd B, Wilhelm KM, McClurkan CL, Margalith M, Liu C, Kaslow D, Sidney J, et al. Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection. J Gen Virol. 2009  ;90(Pt 5):1153-63.

Campbell MS, Gottlieb GS, Hawes SE, Nickle DC, Wong KG, Deng W, Lampinen TM, Kiviat NB, Mullins JI. HIV-1 superinfection in the antiretroviral therapy era: are seroconcordant sexual partners at risk?. PLoS One. 2009  ;4(5):e5690.

Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, Sugerman DE, Druckenmiller JK, Ritger KA, Chugh R, et al. Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med. 2009  ;361(20):1935-44.

Gharib SA, W Liles C, Klaff LS, Altemeier WA. Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics. 2009  ;37(3):239-48.

Palmer GH, Bankhead T, Lukehart SA. 'Nothing is permanent but change'- antigenic variation in persistent bacterial pathogens. Cell Microbiol. 2009  ;11(12):1697-705.

Jain MK, Yuan H-J, Adams-Huet B, Reeck A, Shelton J, Attar N, Zhang S, Neumann AU, Carney DS, Gale M, et al. Pegylated interferon and ribavirin promote early evolution of nonstructural 5A protein in individuals with hepatitis C who demonstrate a response to treatment. J Infect Dis. 2009  ;200(6):866-76.

Stahlhut SG, Chattopadhyay S, Struve C, Weissman SJ, Aprikian P, Libby SJ, Fang FC, Krogfelt KAngeliki, Sokurenko EV. Population variability of the FimH type 1 fimbrial adhesin in Klebsiella pneumoniae. J Bacteriol. 2009  ;191(6):1941-50.

Kraus JM, Verlinde CLMJ, Karimi M, Lepesheva GI, Gelb MH, Buckner FS. Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem. 2009  ;52(6):1639-47.

Morris AE, H Liggitt D, Hawn TR, Skerrett SJ. Role of Toll-like receptor 5 in the innate immune response to acute P. aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 2009  ;297(6):L1112-9.

Serghides L, Patel SN, Ayi K, Lu Z, D Gowda C, W Liles C, Kain KC. Rosiglitazone modulates the innate immune response to Plasmodium falciparum infection and improves outcome in experimental cerebral malaria. J Infect Dis. 2009  ;199(10):1536-45.

Lovegrove FE, Tangpukdee N, Opoka RO, Lafferty EI, Rajwans N, Hawkes M, Krudsood S, Looareesuwan S, John CC, W Liles C, et al. Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One. 2009  ;4(3):e4912.

Helmers AJ, D Gowda C, Kain KC, W Liles C. Statins fail to improve outcome in experimental cerebral malaria and potentiate Toll-like receptor-mediated cytokine production by murine macrophages. Am J Trop Med Hyg. 2009  ;81(4):631-7.

Roxby AC, Gottlieb GS, Limaye AP. Strongyloidiasis in transplant patients. Clin Infect Dis. 2009  ;49(9):1411-23.

Suryadevara PK, Olepu S, Lockman JW, Ohkanda J, Karimi M, Verlinde CLMJ, Kraus JM, Schoepe J, Van Voorhis WC, Hamilton AD, et al. Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease. J Med Chem. 2009  ;52(12):3703-15.

Hukkanen RR, H Liggitt D, Murnane RD, Frevert CW. Systemic inflammatory response syndrome in nonhuman primates culminating in multiple organ failure, acute lung injury, and disseminated intravascular coagulation. Toxicol Pathol. 2009  ;37(6):799-804.

Hawn TR, Scholes D, Li SS, Wang H, Yang Y, Roberts PL, Stapleton AE, Janer M, Aderem A, Stamm WE, et al. Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. PLoS One. 2009  ;4(6):e5990.

Giacani L, Godornes C, Puray-Chavez M, Guerra-Giraldez C, Tompa M, Lukehart SA, Centurion-Lara A. TP0262 is a modulator of promoter activity of tpr Subfamily II genes of Treponema pallidum ssp. pallidum. Mol Microbiol. 2009  ;72(5):1087-99.

Tsai M-H, Ke T-H, Lin H-W, Wu C-C, Chiu S-F, Fang F-C, Liao Y-L, Wong K-T, Chen Y-H, Wu C-I. Triphenylsilyl- and trityl-substituted carbazole-based host materials for blue electrophosphorescence. ACS Appl Mater Interfaces. 2009  ;1(3):567-74.

Boggild AK, Krudsood S, Patel SN, Serghides L, Tangpukdee N, Katz K, Wilairatana P, W Liles C, Looareesuwan S, Kain KC. Use of peroxisome proliferator-activated receptor gamma agonists as adjunctive treatment for Plasmodium falciparum malaria: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis. 2009  ;49(6):841-9.

Conroy AL, Lafferty EI, Lovegrove FE, Krudsood S, Tangpukdee N, W Liles C, Kain KC. Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria. Malar J. 2009  ;8:295.

Milgrom P, Ly KA, Tut OK, Mancl L, Roberts MC, Briand K, Gancio MJane. Xylitol pediatric topical oral syrup to prevent dental caries: a double-blind randomized clinical trial of efficacy. Arch Pediatr Adolesc Med. 2009  ;163(7):601-7.

Yilmaz O, Yao L, Maeda K, Rose TM, Lewis EL, Duman M, Lamont RJ, Ojcius DM. ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis. Cell Microbiol. 2008  ;10(4):863-75.

Patel SN, Berghout J, Lovegrove FE, Ayi K, Conroy A, Serghides L, Min-Oo G, D Gowda C, J Sarma V, Rittirsch D, et al. C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med. 2008  ;205(5):1133-43.

Arakaki TL, Buckner FS, Gillespie RJ, Malmquist NA, Phillips MA, Kalyuzhniy O, Luft JR, Detitta GT, Verlinde CLMJ, Van Voorhis WC, et al. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies. Mol Microbiol. 2008  ;68(1):37-50.

Fang F-C, Cheng Y-L, Lee S-C, Chen J-C, Hsu H-H, Tzao C. Clinical experience of Nuss procedure for pectus excavatum in adult female patients. Thorac Cardiovasc Surg. 2008  ;56(5):283-6.

Main-Hester KL, Colpitts KM, Thomas GA, Fang FC, Libby SJ. Coordinate regulation of Salmonella pathogenicity island 1 (SPI1) and SPI4 in Salmonella enterica serovar Typhimurium. Infect Immun. 2008  ;76(3):1024-35.

Papp-Wallace KM, Nartea M, Kehres DG, Porwollik S, McClelland M, Libby SJ, Fang FC, Maguire ME. The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium. J Bacteriol. 2008  ;190(19):6517-23.

D O'Mahony S, Pham U, Iyer R, Hawn TR, W Liles C. Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages. Int J Med Sci. 2008  ;5(1):1-8.

Loo Y-M, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, et al. Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol. 2008  ;82(1):335-45.

Helmers AJ, Lovegrove FE, Harlan JM, Kain KC, W Liles C. Failure of two distinct anti-apoptotic approaches to reduce mortality in experimental cerebral malaria. Am J Trop Med Hyg. 2008  ;79(6):823-5.

Page AV, W Liles C. Granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and other immunomodulatory therapies for the treatment of infectious diseases in solid organ transplant recipients. Curr Opin Organ Transplant. 2008  ;13(6):575-80.

Lopez JE, Beare PA, Heinzen RA, Norimine J, Lahmers KK, Palmer GH, Brown WC. High-throughput identification of T-lymphocyte antigens from Anaplasma marginale expressed using in vitro transcription and translation. J Immunol Methods. 2008  ;332(1-2):129-41.

Gottlieb GS, Heath L, Nickle DC, Wong KG, Leach SE, Jacobs B, Gezahegne S, Wout AB van 't, Jacobson LP, Margolick JB, et al. HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study. J Infect Dis. 2008  ;197(7):1011-5.

Thuong NThuy Thuon, Dunstan SJ, Chau TThi Hong, Thorsson V, Simmons CP, Quyen NThan Ha, Thwaites GE, Lan NThi Ngoc, Hibberd M, Teo YY, et al. Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles. PLoS Pathog. 2008  ;4(12):e1000229.

Fang F-C, Lee S-C, Hsu H-H, Peng Y-J, Chang H, Cheng Y-L. Inflammatory myofibroblastic tumor of the lung: unusual presentation. Lung. 2008  ;186(3):191-3.

Erdman LK, Finney CAM, W Liles C, Kain KC. Inflammatory pathways in malaria infection: TLRs share the stage with other components of innate immunity. Mol Biochem Parasitol. 2008  ;162(2):105-11.

Caws M, Thwaites G, Dunstan S, Hawn TR, Lan NThi Ngoc, Thuong NThuy Thuon, Stepniewska K, Huyen MNguyet Thu, Bang NDuc, Loc THuu, et al. The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog. 2008  ;4(3):e1000034.

T West E, Frevert CW, H Liggitt D, Skerrett SJ. Inhalation of Burkholderia thailandensis results in lethal necrotizing pneumonia in mice: a surrogate model for pneumonic melioidosis. Trans R Soc Trop Med Hyg. 2008  ;102 Suppl 1:S119-26.

Blohmke CJ, Victor RE, Hirschfeld AF, Elias IM, Hancock DG, Lane CR, A Davidson GF, Wilcox PG, Smith KD, Overhage J, et al. Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease. J Immunol. 2008  ;180(11):7764-73.

Stinear TP, Seemann T, Harrison PF, Jenkin GA, Davies JK, Johnson PDR, Abdellah Z, Arrowsmith C, Chillingworth T, Churcher C, et al. Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. Genome Res. 2008  ;18(5):729-41.

Lesley R, Ramakrishnan L. Insights into early mycobacterial pathogenesis from the zebrafish. Curr Opin Microbiol. 2008  ;11(3):277-83.

Lau DT-Y, Fish PMar, Sinha M, Owen DM, Lemon SM, Gale M. Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. Hepatology. 2008  ;47(3):799-809.

Herbeck JT, Gottlieb GS, Li X, Hu Z, Detels R, Phair J, Rinaldo C, Jacobson LP, Margolick JB, Mullins JI. Lack of evidence for changing virulence of HIV-1 in North America. PLoS One. 2008  ;3(2):e1525.

Chung RT, Gale M, Polyak SJ, Lemon SM, T Liang J, Hoofnagle JH. Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop. Hepatology. 2008  ;47(1):306-20.

Mulligan CJ, Norris SJ, Lukehart SA. Molecular studies in Treponema pallidum evolution: toward clarity?. PLoS Negl Trop Dis. 2008  ;2(1):e184.

Richardson AR, Libby SJ, Fang FC. A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity. Science. 2008  ;319(5870):1672-6.

Marra CM, Maxwell CL, Tantalo LC, Sahi SK, Lukehart SA. Normalization of serum rapid plasma reagin titer predicts normalization of cerebrospinal fluid and clinical abnormalities after treatment of neurosyphilis. Clin Infect Dis. 2008  ;47(7):893-9.

Lovegrove FE, Gharib SA, Peña-Castillo L, Patel SN, Ruzinski JT, Hughes TR, W Liles C, Kain KC. Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog. 2008  ;4(5):e1000068.

Dale DC, Boxer L, W Liles C. The phagocytes: neutrophils and monocytes. Blood. 2008  ;112(4):935-45.

Pepper M, Dzierszinski F, Wilson E, Tait E, Fang Q, Yarovinsky F, Laufer TM, Roos D, Hunter CA. Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines. J Immunol. 2008  ;180(9):6229-36.

Lovegrove FE, Peña-Castillo L, W Liles C, Hughes TR, Kain KC. Plasmodium falciparum shows transcriptional versatility within the human host. Trends Parasitol. 2008  ;24(7):288-91.

Page AV, W Liles C. Posaconazole: A new agent for the prevention and management of severe, refractory or invasive fungal infections. Can J Infect Dis Med Microbiol. 2008  ;19(4):297-305.

Page AV, Evans AJ, Snell L, Liles WC. Primary cutaneous mucormycosis in a lung transplant recipient: case report and concise review of the literature. Transpl Infect Dis. 2008  ;10(6):419-25.

Han S, Norimine J, Palmer GH, Mwangi W, Lahmers KK, Brown WC. Rapid deletion of antigen-specific CD4+ T cells following infection represents a strategy of immune evasion and persistence for Anaplasma marginale. J Immunol. 2008  ;181(11):7759-69.

Ammendola S, Pasquali P, Pacello F, Rotilio G, Castor M, Libby SJ, Figueroa-Bossi N, Bossi L, Fang FC, Battistoni A. Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence. J Biol Chem. 2008  ;283(20):13688-99.

Lukehart SA. Scientific monogamy: thirty years dancing with the same bug: 2007 Thomas Parran Award Lecture. Sex Transm Dis. 2008  ;35(1):2-7.

Su H-C, Chen H-F, Fang F-C, Liu C-C, Wu C-C, Wong K-T, Liu Y-H, Peng S-M. Solid-state white light-emitting electrochemical cells using iridium-based cationic transition metal complexes. J Am Chem Soc. 2008  ;130(11):3413-9.

Fan E, Baker D, Fields S, Gelb MH, Buckner FS, Van Voorhis WC, Phizicky E, Dumont M, Mehlin C, Grayhack E, et al. Structural genomics of pathogenic protozoa: an overview. Methods Mol Biol. 2008  ;426:497-513.

Merritt EA, Holmes M, Buckner FS, Van Voorhis WC, Quartly E, Phizicky EM, Lauricella A, Luft J, Detitta G, Neely H, et al. Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008  ;64(Pt 6):474-8.

Larson ET, Deng W, Krumm BE, Napuli A, Mueller N, Van Voorhis WC, Buckner FS, Fan E, Lauricella A, Detitta G, et al. Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity. J Mol Biol. 2008  ;381(4):975-88.

Massung RF, Hiratzka SL, Brayton KA, Palmer GH, Lee KN. Succinate dehydrogenase gene arrangement and expression in Anaplasma phagocytophilum. Gene. 2008  ;414(1-2):41-8.

Chen C-W, Wu C-C, Hsiao C-W, Fang F-C, Lee T-Y, Che F-C, Tsai W-C, Jao S-W. Surgical management and clinical outcome of gastrointestinal stromal tumor of the colon and rectum. Z Gastroenterol. 2008  ;46(8):760-5.

Riedy CA, Milgrom P, Ly KA, Rothen M, Mueller G, Hagstrom MK, Tolentino E, Zhou L, Roberts MC. A surrogate method for comparison analysis of salivary concentrations of Xylitol-containing products. BMC Oral Health. 2008  ;8:5.

Hann CL, Daniel VC, Sugar EA, Dobromilskaya I, Murphy SC, Cope L, Lin X, Hierman JS, Wilburn DL, D Watkins N, et al. Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer. Cancer Res. 2008  ;68(7):2321-8.

Leverich CK, Palmer GH, Knowles DP, Brayton KA. Tick-borne transmission of two genetically distinct Anaplasma marginale strains following superinfection of the mammalian reservoir host. Infect Immun. 2008  ;76(9):4066-70.

Banas MC, Banas B, Hudkins KL, Wietecha TA, Iyoda M, Bock E, Hauser P, Pippin JW, Shankland SJ, Smith KD, et al. TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol. 2008  ;19(4):704-13.

Yeganeh M, Henneke P, Rezaei N, Ehl S, Thiel D, Matamoros N, Pietrogrande C, Espanol T, Litzman J, Franco JL, et al. Toll-like receptor stimulation induces higher TNF-alpha secretion in peripheral blood mononuclear cells from patients with hyper IgE syndrome. Int Arch Allergy Immunol. 2008  ;146(3):190-4.

Brissette CA, Pham T-TT, Coats SR, Darveau RP, Lukehart SA. Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells. Oral Microbiol Immunol. 2008  ;23(6):474-81.

Page AV, Liles WC. Tumor necrosis factor-alpha inhibitor-induced lupus-like syndrome presenting as fever of unknown origin in a liver transplant recipient: case report and concise review of the literature. Transplant Proc. 2008  ;40(5):1768-70.

Loo Y-M, Gale M. Unveiling viral enablers. Nat Biotechnol. 2008  ;26(10):1093-4.

Ly KA, Riedy CA, Milgrom P, Rothen M, Roberts MC, Zhou L. Xylitol gummy bear snacks: a school-based randomized clinical trial. BMC Oral Health. 2008  ;8:20.

Krupa A, Walencka MJ, Shrivastava V, Loyd T, Fudala R, Frevert CW, Martin TR, Kurdowska AK. Anti-KC autoantibody:KC complexes cause severe lung inflammation in mice via IgG receptors. Am J Respir Cell Mol Biol. 2007  ;37(5):532-43.

Leader BT, Godornes C, VanVoorhis WC, Lukehart SA. CD4+ lymphocytes and gamma interferon predominate in local immune responses in early experimental syphilis. Infect Immun. 2007  ;75(6):3021-6.

Li J, Pritchard DK, Wang X, Park DR, Bumgarner RE, Schwartz SM, W Liles C. cDNA microarray analysis reveals fundamental differences in the expression profiles of primary human monocytes, monocyte-derived macrophages, and alveolar macrophages. J Leukoc Biol. 2007  ;81(1):328-35.

Hawn TR, E Misch A, Dunstan SJ, Thwaites GE, Lan NTN, Quy HT, Chau TTH, Rodrigues S, Nachman A, Janer M, et al. A common human TLR1 polymorphism regulates the innate immune response to lipopeptides. Eur J Immunol. 2007  ;37(8):2280-9.

Gillespie JR, Yokoyama K, Lu K, Eastman RT, Bollinger JG, Van Voorhis WC, Gelb MH, Buckner FS. C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins. Mol Biochem Parasitol. 2007  ;153(2):115-24.

Andersen-Nissen E, Hawn TR, Smith KD, Nachman A, Lampano AE, Uematsu S, Akira S, Aderem A. Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. J Immunol. 2007  ;178(8):4717-20.

Murphy SC, Fernandez-Pol S, Chung PH, Murthy SNPrasanna, Milne SB, Salomao M, H Brown A, Lomasney JW, Mohandas N, Haldar K. Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum. Blood. 2007  ;110(6):2132-9.

Clay H, J Davis M, Beery D, Huttenlocher A, Lyons SE, Ramakrishnan L. Dichotomous role of the macrophage in early Mycobacterium marinum infection of the zebrafish. Cell Host Microbe. 2007  ;2(1):29-39.

Van Voorhis WC, Rivas KL, Bendale P, Nallan L, Hornéy C, Barrett LK, Bauer KD, Smart BP, Ankala S, Hucke O, et al. Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. Antimicrob Agents Chemother. 2007  ;51(10):3659-71.

Matute-Bello G, Wurfel MM, Lee JS, Park DR, Frevert CW, Madtes DK, Shapiro SD, Martin TR. Essential role of MMP-12 in Fas-induced lung fibrosis. Am J Respir Cell Mol Biol. 2007  ;37(2):210-21.

Lovegrove FE, Gharib SA, Patel SN, Hawkes CA, Kain KC, W Liles C. Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria. Am J Pathol. 2007  ;171(6):1894-903.

Altemeier WA, Zhu X, Berrington WR, Harlan JM, W Liles C. Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway. J Leukoc Biol. 2007  ;82(3):721-8.

Tan DHS, Bunce PE, W Liles C, Gold WL. Gemcitabine-related "pseudocellulitis": report of 2 cases and review of the literature. Clin Infect Dis. 2007  ;45(5):e72-6.

Huang H, Sun F, Owen DM, Li W, Chen Y, Gale M, Ye J. Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc Natl Acad Sci U S A. 2007  ;104(14):5848-53.

Lopez JE, Palmer GH, Brayton KA, Dark MJ, Leach SE, Brown WC. Immunogenicity of Anaplasma marginale type IV secretion system proteins in a protective outer membrane vaccine. Infect Immun. 2007  ;75(5):2333-42.

Loo Y-M, Gale M. Influenza: fatal immunity and the 1918 virus. Nature. 2007  ;445(7125):267-8.

Mibayashi M, Martinez-Sobrido L, Loo Y-M, Cárdenas WB, Gale M, García-Sastre A. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J Virol. 2007  ;81(2):514-24.

Lukehart SA, Marra CM. Isolation and laboratory maintenance of Treponema pallidum. Curr Protoc Microbiol. 2007  ;Chapter 12:Unit 12A.1.

Brissette CA, Lukehart SA. Mechanisms of decreased susceptibility to beta-defensins by Treponema denticola. Infect Immun. 2007  ;75(5):2307-15.

Thuong NTT, Hawn TR, Thwaites GE, Chau TTH, Lan NTN, Quy HT, Hieu NT, Aderem A, Hien TT, Farrar JJ, et al. A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis. Genes Immun. 2007  ;8(5):422-8.

Dzierszinski F, Pepper M, Stumhofer JS, LaRosa DF, Wilson EH, Turka LA, Halonen SK, Hunter CA, Roos DS. Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infect Immun. 2007  ;75(11):5200-9.

Mei SHJ, McCarter SD, Deng Y, Parker CH, W Liles C, Stewart DJ. Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med. 2007  ;4(9):e269.

Fox R, Nhan TQ, G Law L, Morris DR, W Liles C, Schwartz SM. PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages. EMBO J. 2007  ;26(2):505-15.

Godornes C, Leader BTroy, Molini BJ, Centurion-Lara A, Lukehart SA. Quantitation of rabbit cytokine mRNA by real-time RT-PCR. Cytokine. 2007  ;38(1):1-7.

Giacani L, Molini B, Godornes C, Barrett L, Van Voorhis W, Centurion-Lara A, Lukehart SA. Quantitative analysis of tpr gene expression in Treponema pallidum isolates: Differences among isolates and correlation with T-cell responsiveness in experimental syphilis. Infect Immun. 2007  ;75(1):104-12.

Saito T, Hirai R, Loo Y-M, Owen D, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M. Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci U S A. 2007  ;104(2):582-7.

Walthers D, Carroll RK, Navarre WWiley, Libby SJ, Fang FC, Kenney LJ. The response regulator SsrB activates expression of diverse Salmonella pathogenicity island 2 promoters and counters silencing by the nucleoid-associated protein H-NS. Mol Microbiol. 2007  ;65(2):477-93.

Zheng NN, McElrath JM, Sow P-S, Hawes SE, Diallo-Agne H, Stern JE, Li F, Mesher AL, Robinson AD, Gottlieb GS, et al. Role of human immunodeficiency virus (HIV)-specific T-cell immunity in control of dual HIV-1 and HIV-2 infection. J Virol. 2007  ;81(17):9061-71.

Bendale P, Olepu S, Suryadevara PK, Bulbule V, Rivas K, Nallan L, Smart B, Yokoyama K, Ankala S, Pendyala PR, et al. Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials. J Med Chem. 2007  ;50(19):4585-605.

Palmer GH, Futse JE, Leverich CK, Knowles DP, Rurangirwa FR, Brayton KA. Selection for simple major surface protein 2 variants during Anaplasma marginale transmission to immunologically naïve animals. Infect Immun. 2007  ;75(3):1502-6.

Navarre WWiley, McClelland M, Libby SJ, Fang FC. Silencing of xenogeneic DNA by H-NS-facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA. Genes Dev. 2007  ;21(12):1456-71.

Arakaki T, Neely H, Boni E, Mueller N, Buckner FS, Van Voorhis WC, Lauricella A, Detitta G, Luft J, Hol WGJ, et al. The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007  ;63(Pt 3):178-82.

Fang F-C, Tzao C, Cheng Y-L, Chan D-C, Nieh S, Lee S-C. Surgical treatment of gastrointestinal stromal tumor in the esophagus: report of three cases. Z Gastroenterol. 2007  ;45(12):1252-6.

Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circ Res. 2007  ;100(11):1589-96.

Loo YM, Gale M. Viral regulation and evasion of the host response. Curr Top Microbiol Immunol. 2007  ;316:295-313.

Marra CM, Colina AP, Godornes C, Tantalo LC, Puray M, Centurion-Lara A, Lukehart SA. Antibiotic selection may contribute to increases in macrolide-resistant Treponema pallidum. J Infect Dis. 2006  ;194(12):1771-3.

LaFond RE, Molini BJ, Van Voorhis WC, Lukehart SA. Antigenic variation of TprK V regions abrogates specific antibody binding in syphilis. Infect Immun. 2006  ;74(11):6244-51.

Mitchell SJ, Engelman J, Kent CK, Lukehart SA, Godornes C, Klausner JD. Azithromycin-resistant syphilis infection: San Francisco, California, 2000-2004. Clin Infect Dis. 2006  ;42(3):337-45.

LaFond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006  ;19(1):29-49.

Zhao X, Wang D, Zhao Z, Xiao Y, Sengupta S, Xiao Y, Zhang R, Lauber K, Wesselborg S, Feng L, et al. Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells. J Biol Chem. 2006  ;281(39):29357-68.

Lee J-H, Murphy SC, Belshan M, Sparks WO, Wannemuehler Y, Liu S, Hope TJ, Dobbs D, Carpenter S. Characterization of functional domains of equine infectious anemia virus Rev suggests a bipartite RNA-binding domain. J Virol. 2006  ;80(8):3844-52.

Montoya PJ, Lukehart SA, Brentlinger PE, Blanco AJ, Floriano F, Sairosse J, Gloyd S. Comparison of the diagnostic accuracy of a rapid immunochromatographic test and the rapid plasma reagin test for antenatal syphilis screening in Mozambique. Bull World Health Organ. 2006  ;84(2):97-104.

Gharib SA, W Liles C, Matute-Bello G, Glenny RW, Martin TR, Altemeier WA. Computational identification of key biological modules and transcription factors in acute lung injury. Am J Respir Crit Care Med. 2006  ;173(6):653-8.

Phan BAn P, Laflamme MA, Stempien-Otero A, Limaye AP, Buckner FS, Levy WC. Confirmation of Chagas' cardiomyopathy following heart transplantation. Heart Vessels. 2006  ;21(5):325-7.

Robien MA, Bosch J, Buckner FS, Van Voorhis WCE, Worthey EA, Myler P, Mehlin C, Boni EE, Kalyuzhniy O, Anderson L, et al. Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site. Proteins. 2006  ;62(3):570-7.

Eck SC, Zhu P, Pepper M, Bensinger SJ, Freedman BD, Laufer TM. Developmental alterations in thymocyte sensitivity are actively regulated by MHC class II expression in the thymic medulla. J Immunol. 2006  ;176(4):2229-37.

Lee JS, Wurfel MM, Matute-Bello G, Frevert CW, Rosengart MR, Ranganathan M, Wong VW, Holden T, Sutlief S, Richmond A, et al. The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation. J Immunol. 2006  ;177(11):8086-94.

Cárdenas WB, Loo Y-M, Gale M, Hartman AL, Kimberlin CR, Martinez-Sobrido L, Saphire EOllmann, Basler CF. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. J Virol. 2006  ;80(11):5168-78.

Murphy SC, Harrison T, Hamm HE, Lomasney JW, Mohandas N, Haldar K. Erythrocyte G protein as a novel target for malarial chemotherapy. PLoS Med. 2006  ;3(12):e528.

Ronald A, Kuypers J, Lukehart SA, Peeling RW, Pope V. Excellence in sexually transmitted infection (STI) diagnostics: recognition of past successes and strategies for the future. Sex Transm Infect. 2006  ;82 Suppl 5:v47-52.

Leader BT, VanVoorhis WC, Lukehart SA. Expression of rabbit interleukin-4 and characterization of its biologic activity on T and B-cells. Vet Immunol Immunopathol. 2006  ;113(3-4):421-7.

Czartoski T, Liu C, Koelle DM, Schmechel S, Kalus A, Wald A. Fulminant, acyclovir-resistant, herpes simplex virus type 2 hepatitis in an immunocompetent woman. J Clin Microbiol. 2006  ;44(4):1584-6.

Chang A, Peutz-Kootstra CJ, Kowalewska J, Logar CM, Gitomer JJ, Davis CL, Shankland SJ, Alpers CE, Smith KD. Giant cell tubulitis with tubular basement membrane immune deposits: a report of two cases after cardiac valve replacement surgery. Clin J Am Soc Nephrol. 2006  ;1(5):920-4.

Mehlin C, Boni E, Buckner FS, Engel L, Feist T, Gelb MH, Haji L, Kim D, Liu C, Mueller N, et al. Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes. Mol Biochem Parasitol. 2006  ;148(2):144-60.

Herbeck JT, Nickle DC, Learn GH, Gottlieb GS, Curlin ME, Heath L, Mullins JI. Human immunodeficiency virus type 1 env evolves toward ancestral states upon transmission to a new host. J Virol. 2006  ;80(4):1637-44.

Ly KA, Milgrom P, Roberts MC, Yamaguchi DK, Rothen M, Mueller G. Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664]. BMC Oral Health. 2006  ;6:6.

Murphy SC, N Hiller L, Harrison T, Lomasney JW, Mohandas N, Haldar K. Lipid rafts and malaria parasite infection of erythrocytes. Mol Membr Biol. 2006  ;23(1):81-8.

Bang I-S, Liu L, Vazquez-Torres A, Crouch M-L, Stamler JS, Fang FC. Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp. J Biol Chem. 2006  ;281(38):28039-47.

Dhanireddy S, Altemeier WA, Matute-Bello G, D O'Mahony S, Glenny RW, Martin TR, W Liles C. Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia. Lab Invest. 2006  ;86(8):790-9.

D O'Mahony S, W Liles C, Altemeier WA, Dhanireddy S, Frevert CW, Liggitt D, Martin TR, Matute-Bello G. Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction. Crit Care. 2006  ;10(5):R136.

Kowalewska J, Smith KD, Hudkins KL, Chang A, Fogo AB, Houghton D, Leslie D, Aitchison J, Nicosia RF, Alpers CE. Membranous glomerulopathy with spherules: an uncommon variant with obscure pathogenesis. Am J Kidney Dis. 2006  ;47(6):983-92.

Wong K-T, Hwu T-Y, Balaiah A, Chao T-C, Fang F-C, Lee C-T, Peng Y-C. Modulation of physical properties of Ter(9,9-ditolylfluorene) by backbone-embedded heteroarenes. Org Lett. 2006  ;8(7):1415-8.

Centurion-Lara A, Molini BJ, Godornes C, Sun E, Hevner K, Van Voorhis WC, Lukehart SA. Molecular differentiation of Treponema pallidum subspecies. J Clin Microbiol. 2006  ;44(9):3377-80.

Gray RR, Mulligan CJ, Molini BJ, Sun ES, Giacani L, Godornes C, Kitchen A, Lukehart SA, Centurion-Lara A. Molecular evolution of the tprC, D, I, K, G, and J genes in the pathogenic genus Treponema. Mol Biol Evol. 2006  ;23(11):2220-33.

Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, et al. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A. 2006  ;103(44):16502-7.

Nhan TQ, W Liles C, Schwartz SM. Physiological functions of caspases beyond cell death. Am J Pathol. 2006  ;169(3):729-37.

Hawn TR, Dunstan SJ, Thwaites GE, Simmons CP, Thuong NThuong, Lan NThi Ngoc, Quy HThi, Chau TThi Hong, Hieu NT, Rodrigues S, et al. A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis. J Infect Dis. 2006  ;194(8):1127-34.

Ojo KK, Ruehlen NL, Close NS, Luis H, Bernardo M, Leitao J, Roberts MC. The presence of a conjugative Gram-positive Tn2009 in Gram-negative commensal bacteria. J Antimicrob Chemother. 2006  ;57(6):1065-9.

Chien Y, Kim S, Bumeister R, Loo Y-M, Kwon SWon, Johnson CL, Balakireva MG, Romeo Y, Kopelovich L, Gale M, et al. RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell. 2006  ;127(1):157-70.

Liu H, Carrington M, Wang C, Holte S, Lee J, Greene B, Hladik F, Koelle DM, Wald A, Kurosawa K, et al. Repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule: effects on HIV-1 susceptibility. J Infect Dis. 2006  ;193(5):698-702.

Navarre WWiley, Porwollik S, Wang Y, McClelland M, Rosen H, Libby SJ, Fang FC. Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella. Science. 2006  ;313(5784):236-8.

Lovegrove FE, Peña-Castillo L, Mohammad N, W Liles C, Hughes TR, Kain KC. Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malaria. BMC Genomics. 2006  ;7:295.

Ojo KK, Striplin MJ, Ulep CC, Close NS, Zittle J, Luis H, Bernardo M, Leitao J, Roberts MC. Staphylococcus efflux msr(A) gene characterized in Streptococcus, Enterococcus, Corynebacterium, and Pseudomonas isolates. Antimicrob Agents Chemother. 2006  ;50(3):1089-91.

Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CLMJ, Mehlin C, Boni E, Detitta G, Luft J, Lauricella A, Anderson L, et al. Structure of ribose 5-phosphate isomerase from Plasmodium falciparum. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006  ;62(Pt 5):427-31.

Holmes MA, Buckner FS, Van Voorhis WC, Mehlin C, Boni E, Earnest TN, Detitta G, Luft J, Lauricella A, Anderson L, et al. Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006  ;62(Pt 3):180-5.

LaFond RE, Centurion-Lara A, Godornes C, Van Voorhis WC, Lukehart SA. TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain. Infect Immun. 2006  ;74(3):1896-906.

Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, Detitta G, et al. Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J Med Chem. 2006  ;49(20):5939-46.

Loo Y-M, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, D Carney S, Wang T, Ishida H, Yoneyama M, et al. Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proc Natl Acad Sci U S A. 2006  ;103(15):6001-6.

Wong K-T, Chen R-T, Fang F-C, Wu C-C, Lin Y-T. 4,5-Diazafluorene-incorporated ter(9,9-diarylfluorene): a novel molecular doping strategy for improving the electron injection property of a highly efficient OLED blue emitter. Org Lett. 2005  ;7(10):1979-82.

W Liles C, Rodger E, Broxmeyer HE, Dehner C, Badel K, Calandra G, Christensen J, Wood B, Price TH, Dale DC. Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist. Transfusion. 2005  ;45(3):295-300.

Matute-Bello G, W Liles C, Frevert CW, Dhanireddy S, Ballman K, Wong V, Green RR, Song HYeong, Witcher DR, Jakubowski JA, et al. Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen. J Infect Dis. 2005  ;191(4):596-606.

Lahmers KK, Norimine J, Abrahamsen MS, Palmer GH, Brown WC. The CD4+ T cell immunodominant Anaplasma marginale major surface protein 2 stimulates gammadelta T cell clones that express unique T cell receptors. J Leukoc Biol. 2005  ;77(2):199-208.

Bergman MA, Cummings LA, Barrett SLRassouli, Smith KD, J Lara C, Aderem A, Cookson BT. CD4+ T cells and toll-like receptors recognize Salmonella antigens expressed in bacterial surface organelles. Infect Immun. 2005  ;73(3):1350-6.

Yaraei K, Campbell LAnn, Zhu X, W Liles C, Kuo C-C, Rosenfeld ME. Chlamydia pneumoniae augments the oxidized low-density lipoprotein-induced death of mouse macrophages by a caspase-independent pathway. Infect Immun. 2005  ;73(7):4315-22.

Foy E, Li K, Sumpter R, Loo Y-M, Johnson CL, Wang C, Fish PMar, Yoneyama M, Fujita T, Lemon SM, et al. Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci U S A. 2005  ;102(8):2986-91.

Navarre WWiley, Halsey TA, Walthers D, Frye J, McClelland M, Potter JL, Kenney LJ, Gunn JS, Fang FC, Libby SJ. Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ. Mol Microbiol. 2005  ;56(2):492-508.

Li K, Chen Z, Kato N, Gale M, Lemon SM. Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem. 2005  ;280(17):16739-47.

Yaraei K, Campbell LAnn, Zhu X, W Liles C, Kuo C-C, Rosenfeld ME. Effect of Chlamydia pneumoniae on cellular ATP content in mouse macrophages: role of Toll-like receptor 2. Infect Immun. 2005  ;73(7):4323-6.

Hübel K, Rodger E, J Gaviria M, Price TH, Dale DC, W Liles C. Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor. Transfusion. 2005  ;45(12):1876-89.

Andersen-Nissen E, Smith KD, Strobe KL, Barrett SLRassouli, Cookson BT, Logan SM, Aderem A. Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci U S A. 2005  ;102(26):9247-52.

Matute-Bello G, Lee JS, W Liles C, Frevert CW, Mongovin S, Wong V, Ballman K, Sutlief S, Martin TR. Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung. J Immunol. 2005  ;175(6):4069-75.

Xiang J, Martinez-Smith C, Gale M, Chang Q, Labrecque DR, Schmidt WN, Stapleton JT. GB virus type C NS5A sequence polymorphisms: association with interferon susceptibility and inhibition of PKR-mediated eIF2alpha phosphorylation. J Interferon Cytokine Res. 2005  ;25(5):261-70.

Kajikawa O, Frevert CW, Lin S-M, Goodman RB, Mongovin SM, Wong V, Ballman K, Daubeuf B, Elson G, Martin TR. Gene expression of Toll-like receptor-2, Toll-like receptor-4, and MD2 is differentially regulated in rabbits with Escherichia coli pneumonia. Gene. 2005  ;344:193-202.

Beard CB, Fox MR, Lawrence GG, Guarner J, Hanzlick RL, Huang L, del Rio C, Rimland D, Duchin JS, Colley DG. Genetic differences in Pneumocystis isolates recovered from immunocompetent infants and from adults with AIDS: Epidemiological Implications. J Infect Dis. 2005  ;192(10):1815-8.

Hawn TR, Ozinsky A, Williams LM, Rodrigues S, Clark A, Pham U, Hill HR, Ochs H, Aderem A, W Liles C. Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes. Hum Immunol. 2005  ;66(7):842-7.

Barbet AF, Agnes JT, Moreland AL, Lundgren AM, A Alleman R, Noh SM, Brayton KA, Munderloh UG, Palmer GH. Identification of functional promoters in the msp2 expression loci of Anaplasma marginale and Anaplasma phagocytophilum. Gene. 2005  ;353(1):89-97.

Lopez JE, Siems WF, Palmer GH, Brayton KA, McGuire TC, Norimine J, Brown WC. Identification of novel antigenic proteins in a complex Anaplasma marginale outer membrane immunogen by mass spectrometry and genomic mapping. Infect Immun. 2005  ;73(12):8109-18.

Li K, Foy E, Ferreon JC, Nakamura M, Ferreon ACM, Ikeda M, Ray SC, Gale M, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A. 2005  ;102(8):2992-7.

Bielefeldt-Ohmann H, Barouch DH, Bakke AM, Bruce AG, Durning M, Grant R, Letvin NL, Ryan JT, Schmidt A, Thouless ME, et al. Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta). Vet Pathol. 2005  ;42(3):391-6.

Fang FC, Libby SJ, Castor ME, Fung AM. Isocitrate lyase (AceA) is required for Salmonella persistence but not for acute lethal infection in mice. Infect Immun. 2005  ;73(4):2547-9.

Fang FC, Sandler N, Libby SJ. Liver abscess caused by magA+ Klebsiella pneumoniae in North America. J Clin Microbiol. 2005  ;43(2):991-2.

Altemeier WA, Matute-Bello G, Gharib SA, Glenny RW, Martin TR, W Liles C. Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol. 2005  ;175(5):3369-76.

Kassim SY, Fu X, W Liles C, Shapiro SD, Parks WC, Heinecke JW. NADPH oxidase restrains the matrix metalloproteinase activity of macrophages. J Biol Chem. 2005  ;280(34):30201-5.

Lack NA, Green B, Dale DC, Calandra GB, Lee H, MacFarland RT, Badel K, Liles WC, Bridger G. A pharmacokinetic-pharmacodynamic model for the mobilization of CD34+ hematopoietic progenitor cells by AMD3100. Clin Pharmacol Ther. 2005  ;77(5):427-36.

Limaye AP, Smith KD, Cook L, Groom DA, Hunt NC, Jerome KR, Boeckh M. Polyomavirus nephropathy in native kidneys of non-renal transplant recipients. Am J Transplant. 2005  ;5(3):614-20.

Nallan L, Bauer KD, Bendale P, Rivas K, Yokoyama K, Hornéy CP, Pendyala PR, Floyd D, Lombardo LJ, Williams DK, et al. Protein farnesyltransferase inhibitors exhibit potent antimalarial activity. J Med Chem. 2005  ;48(11):3704-13.

Broxmeyer HE, Orschell CM, D Clapp W, Hangoc G, Cooper S, P Plett A, W Liles C, Li X, Graham-Evans B, Campbell TB, et al. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med. 2005  ;201(8):1307-18.

Lee WM, Polson JE, D Carney S, Sahin B, Gale M. Reemergence of hepatitis C virus after 8.5 years in a patient with hypogammaglobulinemia: evidence for an occult viral reservoir. J Infect Dis. 2005  ;192(6):1088-92.

Sumpter R, Loo Y-M, Foy E, Li K, Yoneyama M, Fujita T, Lemon SM, Gale M. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol. 2005  ;79(5):2689-99.

Scoles GA, Broce AB, Lysyk TJ, Palmer GH. Relative efficiency of biological transmission of Anaplasma marginale (Rickettsiales: Anaplasmataceae) by Dermacentor andersoni (Acari: Ixodidae) compared with mechanical transmission by Stomoxys calcitrans (Diptera: Muscidae). J Med Entomol. 2005  ;42(4):668-75.

Tyler KM, Luxton GWG, Applewhite DA, Murphy SC, Engman DM. Responsive microtubule dynamics promote cell invasion by Trypanosoma cruzi. Cell Microbiol. 2005  ;7(11):1579-91.

Nhan TQ, W Liles C, Schwartz SM. Role of caspases in death and survival of the plaque macrophage. Arterioscler Thromb Vasc Biol. 2005  ;25(5):895-903.

Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo Y-M, Gale M, Akira S, et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol. 2005  ;175(5):2851-8.

Levy SB, McMurry LM, Roberts MC. Tet protein hybrids. Antimicrob Agents Chemother. 2005  ;49(7):3099.

Lee JS, Frevert CW, Matute-Bello G, Wurfel MM, Wong VA, Lin S-M, Ruzinski J, Mongovin S, Goodman RB, Martin TR. TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia. Am J Physiol Lung Cell Mol Physiol. 2005  ;289(5):L731-8.

Tantalo LC, Lukehart SA, Marra CM. Treponema pallidum strain-specific differences in neuroinvasion and clinical phenotype in a rabbit model. J Infect Dis. 2005  ;191(1):75-80.

Dhanireddy S, W Liles C, Gates GA. Vestibular toxic effects induced by once-daily aminoglycoside therapy. Arch Otolaryngol Head Neck Surg. 2005  ;131(1):46-8.

Marra CM, Maxwell CL, Smith SL, Lukehart SA, Rompalo AM, Eaton M, Stoner BP, Augenbraun M, Barker DE, Corbett JJ, et al. Cerebrospinal fluid abnormalities in patients with syphilis: association with clinical and laboratory features. J Infect Dis. 2004  ;189(3):369-76.

Löhr CV, Brayton KA, Barbet AF, Palmer GH. Characterization of the Anaplasma marginale msp2 locus and its synteny with the omp1/p30 loci of Ehrlichia chaffeensis and E. canis. Gene. 2004  ;325:115-21.

Lober WB, Baer A, Karras BT, Duchin JS. Collection and integration of clinical data for surveillance. Stud Health Technol Inform. 2004  ;107(Pt 2):1211-5.

Norimine J, Mosqueda J, Palmer GH, Lewin HA, Brown WC. Conservation of Babesia bovis small heat shock protein (Hsp20) among strains and definition of T helper cell epitopes recognized by cattle with diverse major histocompatibility complex class II haplotypes. Infect Immun. 2004  ;72(2):1096-106.

Hybiske K, Ichikawa JK, Huang V, Lory SJ, Machen TE. Cystic fibrosis airway epithelial cell polarity and bacterial flagellin determine host response to Pseudomonas aeruginosa. Cell Microbiol. 2004  ;6(1):49-63.

Ohkanda J, Buckner FS, Lockman JW, Yokoyama K, Carrico D, Eastman R, de Luca-Fradley K, Davies W, Croft SL, Van Voorhis WC, et al. Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents. J Med Chem. 2004  ;47(2):432-45.

Lin S-M, Frevert CW, Kajikawa O, Wurfel MM, Ballman K, Mongovin S, Wong VA, Selk A, Martin TR. Differential regulation of membrane CD14 expression and endotoxin-tolerance in alveolar macrophages. Am J Respir Cell Mol Biol. 2004  ;31(2):162-70.

Nakamura M, Matute-Bello G, W Liles C, Hayashi S, Kajikawa O, Lin S-M, Frevert CW, Martin TR. Differential response of human lung epithelial cells to fas-induced apoptosis. Am J Pathol. 2004  ;164(6):1949-58.

Gottlieb GS, Nickle DC, Jensen MA, Wong KG, Grobler J, Li F, Liu S-L, Rademeyer C, Learn GH, Karim SSAbdool, et al. Dual HIV-1 infection associated with rapid disease progression. Lancet. 2004  ;363(9409):619-22.

Murphy SC, Samuel BU, Harrison T, Speicher KD, Speicher DW, Reid ME, Prohaska R, Low PS, Tanner MJ, Mohandas N, et al. Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood. 2004  ;103(5):1920-8.

Halsey TA, Vazquez-Torres A, Gravdahl DJ, Fang FC, Libby SJ. The ferritin-like Dps protein is required for Salmonella enterica serovar Typhimurium oxidative stress resistance and virulence. Infect Immun. 2004  ;72(2):1155-8.

Ogushi K-ichi, Wada A, Niidome T, Okuda T, Llanes R, Nakayama M, Nishi Y, Kurazono H, Smith KD, Aderem A, et al. Gangliosides act as co-receptors for Salmonella enteritidis FliC and promote FliC induction of human beta-defensin-2 expression in Caco-2 cells. J Biol Chem. 2004  ;279(13):12213-9.

Centurion-Lara A, LaFond RE, Hevner K, Godornes C, Molini BJ, Van Voorhis WC, Lukehart SA. Gene conversion: a mechanism for generation of heterogeneity in the tprK gene of Treponema pallidum during infection. Mol Microbiol. 2004  ;52(6):1579-96.

Ojo KK, Tung D, Luis H, Bernardo M, Leitao J, Roberts MC. Gram-positive merA gene in gram-negative oral and urine bacteria. FEMS Microbiol Lett. 2004  ;238(2):411-6.

Lichtenwalner AB, Patton DL, Van Voorhis WC, Sweeney YCT, Kuo C-C. Heat shock protein 60 is the major antigen which stimulates delayed-type hypersensitivity reaction in the macaque model of Chlamydia trachomatis salpingitis. Infect Immun. 2004  ;72(2):1159-61.

Hallstrand TS, Ochs HD, Zhu Q, Liles WC. Inhaled IFN-gamma for persistent nontuberculous mycobacterial pulmonary disease due to functional IFN-gamma deficiency. Eur Respir J. 2004  ;24(3):367-70.

Suarez CE, Palmer GH, LeRoith T, Florin-Christensen M, Crabb B, McElwain TF. Intergenic regions in the rhoptry associated protein-1 (rap-1) locus promote exogenous gene expression in Babesia bovis. Int J Parasitol. 2004  ;34(10):1177-84.

Schapiro JM, Gupta R, Stefansson E, Fang FC, Limaye AP. Isolation of metronidazole-resistant Bacteroides fragilis carrying the nimA nitroreductase gene from a patient in Washington State. J Clin Microbiol. 2004  ;42(9):4127-9.

Hübel K, W Liles C, Broxmeyer HE, Rodger E, Wood B, Cooper S, Hangoc G, Macfarland R, Bridger GJ, Henson GW, et al. Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist. Support Cancer Ther. 2004  ;1(3):165-72.

Lukehart SA, Godornes C, Molini BJ, Sonnett P, Hopkins S, Mulcahy F, Engelman J, Mitchell SJ, Rompalo AM, Marra CM, et al. Macrolide resistance in Treponema pallidum in the United States and Ireland. N Engl J Med. 2004  ;351(2):154-8.

Wong K-T, Fang F-C, Cheng Y-M, Chou P-T, Lee G-H, Wang Y. A new series of pyrimidine-containing linear molecules: their elegant crystal structures and intriguing photophysical properties. J Org Chem. 2004  ;69(23):8038-44.

Marra CM, Maxwell CL, Tantalo L, Eaton M, Rompalo AM, Raines C, Stoner BP, Corbett JJ, Augenbraun M, Zajackowski M, et al. Normalization of cerebrospinal fluid abnormalities after neurosyphilis therapy: does HIV status matter?. Clin Infect Dis. 2004  ;38(7):1001-6.

Matute-Bello G, Lee JS, Frevert CW, W Liles C, Sutlief S, Ballman K, Wong V, Selk A, Martin TR. Optimal timing to repopulation of resident alveolar macrophages with donor cells following total body irradiation and bone marrow transplantation in mice. J Immunol Methods. 2004  ;292(1-2):25-34.

Roberts FA, Houston LS, Lukehart SA, Mancl LA, G Persson R, Page RC. Periodontitis vaccine decreases local prostaglandin E2 levels in a primate model. Infect Immun. 2004  ;72(2):1166-8.

Lin L, Dikeman R, Molini B, Lukehart SA, Lane R, Dupuis K, Metzel P, Corash L. Photochemical treatment of platelet concentrates with amotosalen and long-wavelength ultraviolet light inactivates a broad spectrum of pathogenic bacteria. Transfusion. 2004  ;44(10):1496-504.

Panackal AA, Houze YB, Prentice J, Leopold SS, Cookson BT, W Liles C, Limaye AP. Prosthetic joint infection due to "Helcococcus pyogenes" [corrected]. J Clin Microbiol. 2004  ;42(6):2872-4.

Brissette CA, Simonson LG, Lukehart SA. Resistance to human beta-defensins is common among oral treponemes. Oral Microbiol Immunol. 2004  ;19(6):403-7.

Zaharik ML, Cullen VLi, Fung AM, Libby SJ, Choy SLKujat, Coburn B, Kehres DG, Maguire ME, Fang FC, B Finlay B. The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model. Infect Immun. 2004  ;72(9):5522-5.

Sun ES, Molini BJ, Barrett LK, Centurion-Lara A, Lukehart SA, Van Voorhis WC. Subfamily I Treponema pallidum repeat protein family: sequence variation and immunity. Microbes Infect. 2004  ;6(8):725-37.

Matute-Bello G, Winn RK, Martin TR, W Liles C. Sustained lipopolysaccharide-induced lung inflammation in mice is attenuated by functional deficiency of the Fas/Fas ligand system. Clin Diagn Lab Immunol. 2004  ;11(2):358-61.

Giacani L, Sun ES, Hevner K, Molini BJ, Van Voorhis WC, Lukehart SA, Centurion-Lara A. Tpr homologs in Treponema paraluiscuniculi Cuniculi A strain. Infect Immun. 2004  ;72(11):6561-76.

Sumpter R, Wang C, Foy E, Loo Y-M, Gale M. Viral evolution and interferon resistance of hepatitis C virus RNA replication in a cell culture model. J Virol. 2004  ;78(21):11591-604.

A Lopez M, Hines MT, Palmer GH, Knowles DP, Alperin DC, Hines SA. Analysis of anamnestic immune responses in adult horses and priming in neonates induced by a DNA vaccine expressing the vapA gene of Rhodococcus equi. Vaccine. 2003  ;21(25-26):3815-25.

Leader BT, Hevner K, Molini BJ, Barrett LK, Van Voorhis WC, Lukehart SA. Antibody responses elicited against the Treponema pallidum repeat proteins differ during infection with different isolates of Treponema pallidum subsp. pallidum. Infect Immun. 2003  ;71(10):6054-7.

Liu C-Y, Takemasa A, W Liles C, Goodman RB, Jonas M, Rosen H, Chi E, Winn RK, Harlan JM, Chuang PI. Broad-spectrum caspase inhibition paradoxically augments cell death in TNF-alpha -stimulated neutrophils. Blood. 2003  ;101(1):295-304.

Aprikyan AAG, Kutyavin T, Stein S, Aprikian P, Rodger E, W Liles C, Boxer LA, Dale DC. Cellular and molecular abnormalities in severe congenital neutropenia predisposing to leukemia. Exp Hematol. 2003  ;31(5):372-81.

Buckner F, Yokoyama K, Lockman J, Aikenhead K, Ohkanda J, Sadilek M, Sebti S, Van Voorhis W, Hamilton A, Gelb MH. A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents. Proc Natl Acad Sci U S A. 2003  ;100(25):15149-53.

Hawn TR, Verbon A, Lettinga KD, Zhao LPing, Li SSue, Laws RJ, Skerrett SJ, Beutler B, Schroeder L, Nachman A, et al. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med. 2003  ;198(10):1563-72.

Nickle DC, Jensen MA, Gottlieb GS, Shriner D, Learn GH, Rodrigo AG, Mullins JI. Consensus and ancestral state HIV vaccines. Science. 2003  ;299(5612):1515-8; author reply 1515-8.

Hunter CA, Lieberman LA, Mason N, Pepper M, Sague SL, Tato C, Zediak V. Costimulation in resistance to infection and development of immune pathology: lessons from toxoplasma. Immunol Res. 2003  ;27(2-3):331-40.

Marr KA, S Balajee A, Hawn TR, Ozinsky A, Pham U, Akira S, Aderem A, W Liles C. Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. Infect Immun. 2003  ;71(9):5280-6.

Gottlieb GS, Lesser CF, Holmes KK, Wald A. Disseminated sporotrichosis associated with treatment with immunosuppressants and tumor necrosis factor-alpha antagonists. Clin Infect Dis. 2003  ;37(6):838-40.

Lee JS, Frevert CW, Wurfel MM, Peiper SC, Wong VA, Ballman KK, Ruzinski JT, Rhim JS, Martin TR, Goodman RB. Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo. J Immunol. 2003  ;170(10):5244-51.

Lee JS, Frevert CW, Thorning DR, Segerer S, Alpers CE, Cartron J-P, Colin Y, Wong VA, Martin TR, Goodman RB. Enhanced expression of Duffy antigen in the lungs during suppurative pneumonia. J Histochem Cytochem. 2003  ;51(2):159-66.

Schaub FJ, W Liles C, Ferri N, Sayson K, Seifert RA, Bowen-Pope DF. Fas and Fas-associated death domain protein regulate monocyte chemoattractant protein-1 expression by human smooth muscle cells through caspase- and calpain-dependent release of interleukin-1alpha. Circ Res. 2003  ;93(6):515-22.

Park DR, Thomsen AR, Frevert CW, Pham U, Skerrett SJ, Kiener PA, W Liles C. Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J Immunol. 2003  ;170(12):6209-16.

Koelle DM, Liu Z, McClurkan CL, Cevallos RC, Vieira J, Hosken NA, Meseda CA, Snow DC, Wald A, Corey L. Immunodominance among herpes simplex virus-specific CD8 T cells expressing a tissue-specific homing receptor. Proc Natl Acad Sci U S A. 2003  ;100(22):12899-904.

Schapiro JM, Libby SJ, Fang FC. Inhibition of bacterial DNA replication by zinc mobilization during nitrosative stress. Proc Natl Acad Sci U S A. 2003  ;100(14):8496-501.

W Liles C, Broxmeyer HE, Rodger E, Wood B, Hübel K, Cooper S, Hangoc G, Bridger GJ, Henson GW, Calandra G, et al. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood. 2003  ;102(8):2728-30.

Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, et al. A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J Exp Med. 2003  ;198(5):679-91.

Nhan TQ, W Liles C, Chait A, Fallon JT, Schwartz SM. The p17 cleaved form of caspase-3 is present within viable macrophages in vitro and in atherosclerotic plaque. Arterioscler Thromb Vasc Biol. 2003  ;23(7):1276-82.

Giovanetti E, Brenciani A, Lupidi R, Roberts MC, Varaldo PE. Presence of the tet(O) gene in erythromycin- and tetracycline-resistant strains of Streptococcus pyogenes and linkage with either the mef(A) or the erm(A) gene. Antimicrob Agents Chemother. 2003  ;47(9):2844-9.

Morgan CA, Lukehart SA, Van Voorhis WC. Protection against syphilis correlates with specificity of antibodies to the variable regions of Treponema pallidum repeat protein K. Infect Immun. 2003  ;71(10):5605-12.

Picard C, Puel A, Bonnet M, Ku C-L, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science. 2003  ;299(5615):2076-9.

He Y, Yan W, Coito C, Li Y, Gale M, Katze MG. The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins. J Gen Virol. 2003  ;84(Pt 3):535-43.

Foy E, Li K, Wang C, Sumpter R, Ikeda M, Lemon SM, Gale M. Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science. 2003  ;300(5622):1145-8.

LaFond RE, Centurion-Lara A, Godornes C, Rompalo AM, Van Voorhis WC, Lukehart SA. Sequence diversity of Treponema pallidum subsp. pallidum tprK in human syphilis lesions and rabbit-propagated isolates. J Bacteriol. 2003  ;185(21):6262-8.

Van Voorhis WC, Barrett LK, Lukehart SA, Schmidt B, Schriefer M, Cameron CE. Serodiagnosis of syphilis: antibodies to recombinant Tp0453, Tp92, and Gpd proteins are sensitive and specific indicators of infection by Treponema pallidum. J Clin Microbiol. 2003  ;41(8):3668-74.

Lober WB, Trigg LJ, Karras BT, Bliss D, Ciliberti J, Stewart L, Duchin JS. Syndromic surveillance using automated collection of computerized discharge diagnoses. J Urban Health. 2003  ;80(2 Suppl 1):i97-106.

Means TK, Hayashi F, Smith KD, Aderem A, Luster AD. The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells. J Immunol. 2003  ;170(10):5165-75.

Testerman TL, Vazquez-Torres A, Xu Y, Jones-Carson J, Libby SJ, Fang FC. The alternative sigma factor sigmaE controls antioxidant defences required for Salmonella virulence and stationary-phase survival. Mol Microbiol. 2002  ;43(3):771-82.

Brayton KA, Palmer GH, Lundgren A, Yi J, Barbet AF. Antigenic variation of Anaplasma marginale msp2 occurs by combinatorial gene conversion. Mol Microbiol. 2002  ;43(5):1151-9.

Imanishi T, Han DK, Hofstra L, Hano T, Nishio I, W Liles C, Gown AM, Schwartz SM, Han DKM, Gorden AM. Apoptosis of vascular smooth muscle cells is induced by Fas ligand derived from monocytes/macrophage. Atherosclerosis. 2002  ;161(1):143-51.

O'Regan AW, Castro C, Lukehart SA, Kasznica JM, Rice PA, Joyce-Brady MF. Barking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis. Thorax. 2002  ;57(10):917-8.

Geisler WM, Harrington RD, Wallis CK, Harnisch JP, W Liles C. Broad spectrum of dermatologic manifestations caused by Mycobacterium haemophilum infection. Arch Dermatol. 2002  ;138(2):229-30.

Luna VA, Heiken M, Judge K, Ulep C, van Kirk N, Luis H, Bernardo M, Leitao J, Roberts MC. Distribution of mef(A) in gram-positive bacteria from healthy Portuguese children. Antimicrob Agents Chemother. 2002  ;46(8):2513-7.

Mwangi W, Brown WC, Lewin HA, Howard CJ, Hope JC, Baszler TV, Caplazi P, Abbott J, Palmer GH. DNA-encoded fetal liver tyrosine kinase 3 ligand and granulocyte macrophage-colony-stimulating factor increase dendritic cell recruitment to the inoculation site and enhance antigen-specific CD4+ T cell responses induced by DNA vaccination of outbred anim. J Immunol. 2002  ;169(7):3837-46.

Antal GMichael, Lukehart SA, Meheus AZ. The endemic treponematoses. Microbes Infect. 2002  ;4(1):83-94.

Löhr CV, Brayton KA, Shkap V, Molad T, Barbet AF, Brown WC, Palmer GH. Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infection. Infect Immun. 2002  ;70(11):6005-12.

Koelle DM, Liu Z, McClurkan CM, Topp MS, Riddell SR, Pamer EG, Johnson AS, Wald A, Corey L. Expression of cutaneous lymphocyte-associated antigen by CD8(+) T cells specific for a skin-tropic virus. J Clin Invest. 2002  ;110(4):537-48.

Henderson S, Leibnitz G, Turnbull M, Palmer GH. False-positive human immunodeficiency virus seroconversion is not common following rabies vaccination. Clin Diagn Lab Immunol. 2002  ;9(4):942-3.

Lu S, Killoran PB, Fang FC, Riley LW. The global regulator ArcA controls resistance to reactive nitrogen and oxygen intermediates in Salmonella enterica serovar Enteritidis. Infect Immun. 2002  ;70(2):451-61.

Hübel K, Carter RA, W Liles C, Dale DC, Price TH, Bowden RA, Rowley SD, Chauncey TR, Bensinger WI, Boeckh M. Granulocyte transfusion therapy for infections in candidates and recipients of HPC transplantation: a comparative analysis of feasibility and outcome for community donors versus related donors. Transfusion. 2002  ;42(11):1414-21.

Limaye AP, Raghu G, Koelle DM, Ferrenberg J, Huang M-L, Boeckh M. High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy. J Infect Dis. 2002  ;185(1):20-7.

Roberts MC, Riedy CA, Coldwell SE, Nagahama S, Judge K, Lam M, Kaakko T, Castillo JL, Milgrom P. How xylitol-containing products affect cariogenic bacteria. J Am Dent Assoc. 2002  ;133(4):435-41; quiz 492-3.

A Lopez M, Hines MT, Palmer GH, Alperin DC, Hines SA. Identification of pulmonary T-lymphocyte and serum antibody isotype responses associated with protection against Rhodococcus equi. Clin Diagn Lab Immunol. 2002  ;9(6):1270-6.

Morgan CA, Lukehart SA, Van Voorhis WC. Immunization with the N-terminal portion of Treponema pallidum repeat protein K attenuates syphilitic lesion development in the rabbit model. Infect Immun. 2002  ;70(12):6811-6.

Karvar S, Yao X, Duman JG, Hybiske K, Liu Y, Forte JG. Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells. Gastroenterology. 2002  ;123(1):281-90.

Kaushansky K, Fox N, Lin NL, W Liles C. Lineage-specific growth factors can compensate for stem and progenitor cell deficiencies at the postprogenitor cell level: an analysis of doubly TPO- and G-CSF receptor-deficient mice. Blood. 2002  ;99(10):3573-8.

Brown WC, McGuire TC, Mwangi W, Kegerreis KA, Macmillan H, Lewin HA, Palmer GH. Major histocompatibility complex class II DR-restricted memory CD4(+) T lymphocytes recognize conserved immunodominant epitopes of Anaplasma marginale major surface protein 1a. Infect Immun. 2002  ;70(10):5521-32.

Aprikyan AAG, W Liles C, Boxer LA, Dale DC. Mutant elastase in pathogenesis of cyclic and severe congenital neutropenia. J Pediatr Hematol Oncol. 2002  ;24(9):784-6.

Lewis CW, Riedy CA, Grossman DC, Domoto PK, Roberts MC. Oral health of young Alaska Native children and their caregivers in Southwestern Alaska. Alaska Med. 2002  ;44(4):83-7.

Sanai Y, G Persson R, Starr JR, Luis HS, Bernardo M, Leitao J, Roberts MC. Presence and antibiotic resistance of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens in children. J Clin Periodontol. 2002  ;29(10):929-34.

J Davis M, Clay H, Lewis JL, Ghori N, Herbomel P, Ramakrishnan L. Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. Immunity. 2002  ;17(6):693-702.

Morgan CA, Molini BJ, Lukehart SA, Van Voorhis WC. Segregation of B and T cell epitopes of Treponema pallidum repeat protein K to variable and conserved regions during experimental syphilis infection. J Immunol. 2002  ;169(2):952-7.

Löhr CV, Rurangirwa FR, McElwain TF, Stiller D, Palmer GH. Specific expression of Anaplasma marginale major surface protein 2 salivary gland variants occurs in the midgut and is an early event during tick transmission. Infect Immun. 2002  ;70(1):114-20.

Hübel K, Dale DC, W Liles C. Therapeutic use of cytokines to modulate phagocyte function for the treatment of infectious diseases: current status of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and inte. J Infect Dis. 2002  ;185(10):1490-501.

Brissette CA, Lukehart SA. Treponema denticola is resistant to human beta-defensins. Infect Immun. 2002  ;70(7):3982-4.

Buckner FS, Kateete DP, Lubega GW, Van Voorhis WC, Yokoyama K. Trypanosoma brucei prenylated-protein carboxyl methyltransferase prefers farnesylated substrates. Biochem J. 2002  ;367(Pt 3):809-16.

Gottlieb GS, Limaye AP, Chen YC, Van Voorhis WC. Candida dubliniensis fungemia in a solid organ transplant patient: case report and review of the literature. Med Mycol. 2001  ;39(6):483-5.

Brown WC, Palmer GH, Lewin HA, McGuire TC. CD4(+) T lymphocytes from calves immunized with Anaplasma marginale major surface protein 1 (MSP1), a heteromeric complex of MSP1a and MSP1b, preferentially recognize the MSP1a carboxyl terminus that is conserved among strains. Infect Immun. 2001  ;69(11):6853-62.

Dale DC, Liles WC, Garwicz D, Aprikyan AG. Clinical implications of mutations of neutrophil elastase in congenital and cyclic neutropenia. J Pediatr Hematol Oncol. 2001  ;23(4):208-10.

Hübel K, Dale DC, Engert A, Liles WC. Current status of granulocyte (neutrophil) transfusion therapy for infectious diseases. J Infect Dis. 2001  ;183(2):321-328.

Piddington DL, Fang FC, Laessig T, Cooper AM, Orme IM, Buchmeier NA. Cu,Zn superoxide dismutase of Mycobacterium tuberculosis contributes to survival in activated macrophages that are generating an oxidative burst. Infect Immun. 2001  ;69(8):4980-7.

Matute-Bello G, Winn RK, Jonas M, Chi EY, Martin TR, Liles WC. Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: implications for acute pulmonary inflammation. Am J Pathol. 2001  ;158(1):153-61.

Matute-Bello G, Frevert CW, Liles WC, Nakamura M, Ruzinski JT, Ballman K, Wong VA, Vathanaprida C, Martin TR. Fas/Fas ligand system mediates epithelial injury, but not pulmonary host defenses, in response to inhaled bacteria. Infect Immun. 2001  ;69(9):5768-76.

Hübel K, Dale DC, Liles WC. Granulocyte transfusion therapy: update on potential clinical applications. Curr Opin Hematol. 2001  ;8(3):161-4.

Brown WC, McGuire TC, Zhu D, Lewin HA, Sosnow J, Palmer GH. Highly conserved regions of the immunodominant major surface protein 2 of the genogroup II ehrlichial pathogen Anaplasma marginale are rich in naturally derived CD4+ T lymphocyte epitopes that elicit strong recall responses. J Immunol. 2001  ;166(2):1114-24.

Greenblatt RM, Jacobson LP, Levine AM, Melnick S, Anastos K, Cohen M, DeHovitz J, Young MA, Burns D, Miotti P, et al. Human herpesvirus 8 infection and Kaposi's sarcoma among human immunodeficiency virus-infected and -uninfected women. J Infect Dis. 2001  ;183(7):1130-4.

Liles WC. Immunomodulatory approaches to augment phagocyte-mediated host defense for treatment of infectious diseases. Semin Respir Infect. 2001  ;16(1):11-7.

Aprikyan AA, Liles WC, Rodger E, Jonas M, Chi EY, Dale DC. Impaired survival of bone marrow hematopoietic progenitor cells in cyclic neutropenia. Blood. 2001  ;97(1):147-53.

Allen CA, Fedorka-Cray PJ, Vazquez-Torres A, Suyemoto M, Altier C, Ryder LR, Fang FC, Libby SJ. In vitro and in vivo assessment of Salmonella enterica serovar Typhimurium DT104 virulence. Infect Immun. 2001  ;69(7):4673-7.

Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, et al. New ways of initiating translation in eukaryotes. Mol Cell Biol. 2001  ;21(23):8238-46.

Stamler JS, Lamas S, Fang FC. Nitrosylation. the prototypic redox-based signaling mechanism. Cell. 2001  ;106(6):675-83.

Kwok WW, Gebe JA, Liu A, Agar S, Ptacek N, Hammer J, Koelle DM, Nepom GT. Rapid epitope identification from complex class-II-restricted T-cell antigens. Trends Immunol. 2001  ;22(11):583-8.

Matute-Bello G, Liles WC, Frevert CW, Nakamura M, Ballman K, Vathanaprida C, Kiener PA, Martin TR. Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits. Am J Physiol Lung Cell Mol Physiol. 2001  ;281(2):L328-35.

Liles WC, Thomsen AR, O'Mahony DS, Klebanoff SJ. Stimulation of human neutrophils and monocytes by staphylococcal phenol-soluble modulin. J Leukoc Biol. 2001  ;70(1):96-102.

Nepomuceno-Silva JL, Yokoyama K, de Mello LD, Mendonca SM, Paixão JC, Baron R, Faye JC, Buckner FS, Van Voorhis WC, Gelb MH, et al. TcRho1, a farnesylated Rho family homologue from Trypanosoma cruzi: cloning, trans-splicing, and prenylation studies. J Biol Chem. 2001  ;276(32):29711-8.

Novak EJ, Liu AW, Gebe JA, Falk BA, Nepom GT, Koelle DM, Kwok WW. Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens. J Immunol. 2001  ;166(11):6665-70.

Barbet AF, Lundgren A, Yi J, Rurangirwa FR, Palmer GH. Antigenic variation of Anaplasma marginale by expression of MSP2 mosaics. Infect Immun. 2000  ;68(11):6133-8.

Imanishi T, Murry CE, Reinecke H, Hano T, Nishio I, Liles WC, Hofsta L, Kim K, O'Brien KD, Schwartz SM, et al. Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues. Cardiovasc Res. 2000  ;48(1):101-10.

Liles WC, Rodger E, Dale DC. Combined administration of G-CSF and dexamethasone for the mobilization of granulocytes in normal donors: optimization of dosing. Transfusion. 2000  ;40(6):642-4.

Limaye AP, Corey L, Koelle DM, Davis CL, Boeckh M. Emergence of ganciclovir-resistant cytomegalovirus disease among recipients of solid-organ transplants. Lancet. 2000  ;356(9230):645-9.

Aprikyan AA, Liles WC, Dale DC. Emerging role of apoptosis in the pathogenesis of severe neutropenia. Curr Opin Hematol. 2000  ;7(3):131-2.

Schaub FJ, Han DK, Liles WC, Adams LD, Coats SA, Ramachandran RK, Seifert RA, Schwartz SM, Bowen-Pope DF. Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells. Nat Med. 2000  ;6(7):790-6.

Beard CB, Carter JL, Keely SP, Huang L, Pieniazek NJ, Moura IN, Roberts JM, Hightower AW, Bens MS, Freeman AR, et al. Genetic variation in Pneumocystis carinii isolates from different geographic regions: implications for transmission. Emerg Infect Dis. 2000  ;6(3):265-72.

Kwok WW, Liu AW, Novak EJ, Gebe JA, Ettinger RA, Nepom GT, Reymond SN, Koelle DM. HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: direct detection of immunodominant antigen-responsive cells. J Immunol. 2000  ;164(8):4244-9.

Liles WC, Dale DC, Price TH, Gaviria JM, Turner T, Saoud J, Frumkin LR. Inhibition of in vivo neutrophil transmigration by a novel humanized anti-CD11/CD18 monoclonal antibody. Cytokines Cell Mol Ther. 2000  ;6(3):121-6.

Xie H, Cook GS, Costerton JW, Bruce G, Rose TM, Lamont RJ. Intergeneric communication in dental plaque biofilms. J Bacteriol. 2000  ;182(24):7067-9.

Engelfriet CP, Reesink HW, Klein HG, Murphy MF, Pamphilon D, Devereux S, Höcker P, Adkins D, Boyce N, Tobin S, et al. International forum: granulocyte transfusions. Vox Sang. 2000  ;79(1):59-66.

Matute-Bello G, Liles WC, Radella F, Steinberg KP, Ruzinski JT, Hudson LD, Martin TR. Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor during the course of acute respiratory distress syndrome. Crit Care Med. 2000  ;28(1):1-7.

Centurion-Lara A, Sun ES, Barrett LK, Castro C, Lukehart SA, Van Voorhis WC. Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates. J Bacteriol. 2000  ;182(8):2332-5.

Aprikyan AA, Liles WC, Park JR, Jonas M, Chi EY, Dale DC. Myelokathexis, a congenital disorder of severe neutropenia characterized by accelerated apoptosis and defective expression of bcl-x in neutrophil precursors. Blood. 2000  ;95(1):320-7.

Cameron CE, Lukehart SA, Castro C, Molini B, Godornes C, Van Voorhis WC. Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp92. J Infect Dis. 2000  ;181(4):1401-13.

Price TH, Bowden RA, Boeckh M, Bux J, Nelson K, Liles WC, Dale DC. Phase I/II trial of neutrophil transfusions from donors stimulated with G-CSF and dexamethasone for treatment of patients with infections in hematopoietic stem cell transplantation. Blood. 2000  ;95(11):3302-9.

Gopal AK, Fowler VG, Shah M, Gesty-Palmer D, Marr KA, McClelland RS, Kong LK, Gottlieb GS, Lanclos K, Li J, et al. Prospective analysis of Staphylococcus aureus bacteremia in nonneutropenic adults with malignancy. J Clin Oncol. 2000  ;18(5):1110-5.

Dale DC, Liles WC. Return of granulocyte transfusions. Curr Opin Pediatr. 2000  ;12(1):18-22.

Vazquez-Torres A, Xu Y, Jones-Carson J, Holden DW, Lucia SM, Dinauer MC, Mastroeni P, Fang FC. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science. 2000  ;287(5458):1655-8.

Gottlieb GS, Fowler VG, Kong LK, McClelland RS, Gopal AK, Marr KA, Li J, Sexton DJ, Glower D, Corey GR. Staphylococcus aureus bacteremia in the surgical patient: a prospective analysis of 73 postoperative patients who developed Staphylococcus aureus bacteremia at a tertiary care facility. J Am Coll Surg. 2000  ;190(1):50-7.

Huang L, Beard CB, Creasman J, Levy D, Duchin JS, Lee S, Pieniazek N, Carter JL, del Rio C, Rimland D, et al. Sulfa or sulfone prophylaxis and geographic region predict mutations in the Pneumocystis carinii dihydropteroate synthase gene. J Infect Dis. 2000  ;182(4):1192-8.

Centurion-Lara A, Godornes C, Castro C, Van Voorhis WC, Lukehart SA. The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles. Infect Immun. 2000  ;68(2):824-31.

Imanishi T, Hano T, Nishio I, Liles WC, Schwartz SM, Han DK. Transition of apoptotic resistant vascular smooth muscle cells to troptotic sensitive state is correlated with downregulation of c-FLIP. J Vasc Res. 2000  ;37(6):523-31.

Hübel K, Dale DC, Engert A, Liles WC. Use of G-CSF for granulocyte transfusion therapy. Cytokines Cell Mol Ther. 2000  ;6(2):89-95.

Lu S, Manges AR, Xu Y, Fang FC, Riley LW. Analysis of virulence of clinical isolates of Salmonella enteritidis in vivo and in vitro. Infect Immun. 1999  ;67(11):5651-7.

Gaviria JM, van Burik JA, Dale DC, Root RK, Liles WC. Comparison of interferon-gamma, granulocyte colony-stimulating factor, and granulocyte-macrophage colony-stimulating factor for priming leukocyte-mediated hyphal damage of opportunistic fungal pathogens. J Infect Dis. 1999  ;179(4):1038-41.

Weston D, La Flamme AC, Van Voorhis WC. Expression of Trypanosoma cruzi surface antigen FL-160 is controlled by elements in the 3' untranslated, the 3' intergenic, and the coding regions. Mol Biochem Parasitol. 1999  ;102(1):53-66.

Vazquez-Torres A, Jones-Carson J, Bäumler AJ, Falkow S, Valdivia R, Brown W, Le M, Berggren R, Parks WT, Fang FC. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. Nature. 1999  ;401(6755):804-8.

Houston LS, Lukehart SA, Persson GR, Page RC. Function of anti-Porphyromonas gingivalis immunoglobulin classes in immunized Macaca fascicularis. Oral Microbiol Immunol. 1999  ;14(2):86-91.

Lundberg BE, Wolf RE, Dinauer MC, Xu Y, Fang FC. Glucose 6-phosphate dehydrogenase is required for Salmonella typhimurium virulence and resistance to reactive oxygen and nitrogen intermediates. Infect Immun. 1999  ;67(1):436-8.

Kolman CJ, Centurion-Lara A, Lukehart SA, Owsley DW, Tuross N. Identification of Treponema pallidum subspecies pallidum in a 200-year-old skeletal specimen. J Infect Dis. 1999  ;180(6):2060-3.

Fowler VG, Sanders LL, Kong LK, McClelland RS, Gottlieb GS, Li J, Ryan T, Sexton DJ, Roussakis G, Harrell LJ, et al. Infective endocarditis due to Staphylococcus aureus: 59 prospectively identified cases with follow-up. Clin Infect Dis. 1999  ;28(1):106-14.

Lurton J, Rose TM, Raghu G, Narayanan AS. Isolation of a gene product expressed by a subpopulation of human lung fibroblasts by differential display. Am J Respir Cell Mol Biol. 1999  ;20(2):327-31.

Gaviria JM, van Burik JA, Dale DC, Root RK, Liles WC. Modulation of neutrophil-mediated activity against the pseudohyphal form of Candida albicans by granulocyte colony-stimulating factor (G-CSF) administered in vivo. J Infect Dis. 1999  ;179(5):1301-4.

Cameron CE, Castro C, Lukehart SA, Van Voorhis WC. Sequence conservation of glycerophosphodiester phosphodiesterase among Treponema pallidum strains. Infect Immun. 1999  ;67(6):3168-70.

Broudy VC, Lin NL, Liles WC, Corey SJ, O'Laughlin B, Mou S, Linnekin D. Signaling via Src family kinases is required for normal internalization of the receptor c-Kit. Blood. 1999  ;94(6):1979-86.

Matute-Bello G, Liles WC, Steinberg KP, Kiener PA, Mongovin S, Chi EY, Jonas M, Martin TR. Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J Immunol. 1999  ;163(4):2217-25.

Barkan SE, Leonetti AM, Hopkins SG, Duchin JS. Substantial decrease in numbers and rates of AIDS deaths over the last decade. J Acquir Immune Defic Syndr. 1999  ;22(3):312-4.

Arroll TW, Centurion-Lara A, Lukehart SA, Van Voorhis WC. T-Cell responses to Treponema pallidum subsp. pallidum antigens during the course of experimental syphilis infection. Infect Immun. 1999  ;67(9):4757-63.

Centurion-Lara A, Castro C, Barrett L, Cameron C, Mostowfi M, Van Voorhis WC, Lukehart SA. Treponema pallidum major sheath protein homologue Tpr K is a target of opsonic antibody and the protective immune response. J Exp Med. 1999  ;189(4):647-56.

Fang FC, DeGroote MA, Foster JW, Bäumler AJ, Ochsner U, Testerman T, Bearson S, Giárd JC, Xu Y, Campbell G, et al. Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases. Proc Natl Acad Sci U S A. 1999  ;96(13):7502-7.

van Besien K, Sobocinski KA, Rowlings PA, Murphy SC, Armitage JO, Bishop MR, Chaekal OK, Gale RP, Klein JP, Lazarus HM, et al. Allogeneic bone marrow transplantation for low-grade lymphoma. Blood. 1998  ;92(5):1832-6.

Swetter SM, Hill EL, Kern ER, Koelle DM, Posavad CM, Lawrence W, Safrin S. Chronic vulvar ulceration in an immunocompetent woman due to acyclovir-resistant, thymidine kinase-deficient herpes simplex virus. J Infect Dis. 1998  ;177(3):543-50.

Dale DC, Liles WC, Llewellyn C, Price TH. Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) on neutrophil kinetics and function in normal human volunteers. Am J Hematol. 1998  ;57(1):7-15.

Centurion-Lara A, Castro C, Castillo R, Shaffer JM, Van Voorhis WC, Lukehart SA. The flanking region sequences of the 15-kDa lipoprotein gene differentiate pathogenic treponemes. J Infect Dis. 1998  ;177(4):1036-40.

Cameron CE, Castro C, Lukehart SA, Van Voorhis WC. Function and protective capacity of Treponema pallidum subsp. pallidum glycerophosphodiester phosphodiesterase. Infect Immun. 1998  ;66(12):5763-70.

Marra CM, Castro CD, Kuller L, Dukes AC, Centurion-Lara A, Morton WR, Lukehart SA. Mechanisms of clearance of Treponema pallidum from the CSF in a nonhuman primate model. Neurology. 1998  ;51(4):957-61.

Dale DC, Liles WC, Llewellyn C, Rodger E, Price TH. Neutrophil transfusions: kinetics and functions of neutrophils mobilized with granulocyte-colony-stimulating factor and dexamethasone. Transfusion. 1998  ;38(8):713-21.

Bauer TR, Schwartz BR, Liles WC, Ochs HD, Hickstein DD. Retroviral-mediated gene transfer of the leukocyte integrin CD18 into peripheral blood CD34+ cells derived from a patient with leukocyte adhesion deficiency type 1. Blood. 1998  ;91(5):1520-6.

Doherty DG, Penzotti JE, Koelle DM, Kwok WW, Lybrand TP, Masewicz S, Nepom GT. Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR. J Immunol. 1998  ;161(7):3527-35.

Liles WC, Huang JE, Llewellyn C, SenGupta D, Price TH, Dale DC. A comparative trial of granulocyte-colony-stimulating factor and dexamethasone, separately and in combination, for the mobilization of neutrophils in the peripheral blood of normal volunteers. Transfusion. 1997  ;37(2):182-7.

Centurion-Lara A, Arroll T, Castillo R, Shaffer JM, Castro C, Van Voorhis WC, Lukehart SA. Conservation of the 15-kilodalton lipoprotein among Treponema pallidum subspecies and strains and other pathogenic treponemes: genetic and antigenic analyses. Infect Immun. 1997  ;65(4):1440-4.

Centurion-Lara A, Castro C, Shaffer JM, Van Voorhis WC, Marra CM, Lukehart SA. Detection of Treponema pallidum by a sensitive reverse transcriptase PCR. J Clin Microbiol. 1997  ;35(6):1348-52.

Kiener PA, Davis PM, Starling GC, Mehlin C, Klebanoff SJ, Ledbetter JA, Liles WC. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages. J Exp Med. 1997  ;185(8):1511-6.

Liles WC, Huang JE, van Burik JA, Bowden RA, Dale DC. Granulocyte colony-stimulating factor administered in vivo augments neutrophil-mediated activity against opportunistic fungal pathogens. J Infect Dis. 1997  ;175(4):1012-5.

Kiener PA, Davis PM, Rankin BM, Klebanoff SJ, Ledbetter JA, Starling GC, Liles WC. Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. J Immunol. 1997  ;159(4):1594-8.

Stebeck CE, Shaffer JM, Arroll TW, Lukehart SA, Van Voorhis WC. Identification of the Treponema pallidum subsp. pallidum glycerophosphodiester phosphodiesterase homologue. FEMS Microbiol Lett. 1997  ;154(2):303-10.

Matute-Bello G, Liles WC, Radella F, Steinberg KP, Ruzinski JT, Jonas M, Chi EY, Hudson LD, Martin TR. Neutrophil apoptosis in the acute respiratory distress syndrome. Am J Respir Crit Care Med. 1997  ;156(6):1969-77.

De Groote MA, Ochsner UA, Shiloh MU, Nathan C, McCord JM, Dinauer MC, Libby SJ, Vazquez-Torres A, Xu Y, Fang FC. Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase. Proc Natl Acad Sci U S A. 1997  ;94(25):13997-4001.

Dale DC, Liles WC, Price TH. Renewed interest in granulocyte transfusion therapy. Br J Haematol. 1997  ;98(3):497-501.

Limaye AP, Paauw D, Raghu G, Schmidt RA, Liles WC. Sarcoidosis associated with recurrent pancreatitis. South Med J. 1997  ;90(4):431-3.

Buchmeier N, Bossie S, Chen CY, Fang FC, Guiney DG, Libby SJ. SlyA, a transcriptional regulator of Salmonella typhimurium, is required for resistance to oxidative stress and is expressed in the intracellular environment of macrophages. Infect Immun. 1997  ;65(9):3725-30.

La Flamme AC, Kahn SJ, Rudensky AY, Van Voorhis WC. Trypanosoma cruzi-infected macrophages are defective in major histocompatibility complex class II antigen presentation. Eur J Immunol. 1997  ;27(12):3085-94.

Cummings MC, Lukehart SA, Marra C, Smith BL, Shaffer J, Demeo LR, Castro C, McCormack WM. Comparison of methods for the detection of treponema pallidum in lesions of early syphilis. Sex Transm Dis. 1996  ;23(5):366-9.

Liles WC, Kiener PA, Ledbetter JA, Aruffo A, Klebanoff SJ. Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils. J Exp Med. 1996  ;184(2):429-40.

Buckner FS, Verlinde CL, La Flamme AC, Van Voorhis WC. Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase. Antimicrob Agents Chemother. 1996  ;40(11):2592-7.

Buchwald D, Collier AC, Lukehart SA, Kith P, Goldstein E, Hooton TM. Evaluation of cerebrospinal fluid in Southeast Asian refugees with reactive serologic tests for syphilis. West J Med. 1996  ;165(5):289-93.

Eid G, French DM, Lundgren AM, Barbet AF, McElwain TF, Palmer GH. Expression of major surface protein 2 antigenic variants during acute Anaplasma marginale rickettsemia. Infect Immun. 1996  ;64(3):836-41.

Chen CY, Eckmann L, Libby SJ, Fang FC, Okamoto S, Kagnoff MF, Fierer J, Guiney DG. Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infect Immun. 1996  ;64(11):4739-43.

Van Voorhis WC, Barrett LK, Nasio JM, Plummer FA, Lukehart SA. Lesions of primary and secondary syphilis contain activated cytolytic T cells. Infect Immun. 1996  ;64(3):1048-50.

Van Voorhis WC, Barrett LK, Koelle DM, Nasio JM, Plummer FA, Lukehart SA. Primary and secondary syphilis lesions contain mRNA for Th1 cytokines. J Infect Dis. 1996  ;173(2):491-5.

Marra CM, Longstreth WT, Maxwell CL, Lukehart SA. Resolution of serum and cerebrospinal fluid abnormalities after treatment of neurosyphilis. Influence of concomitant human immunodeficiency virus infection. Sex Transm Dis. 1996  ;23(3):184-9.

Long NC, Frevert CW, Shore SA. Role of C fibers in the inflammatory response to intratracheal lipopolysaccharide. Am J Physiol. 1996  ;271(3 Pt 1):L425-31.

La Flamme AC, Buckner FS, Swindle J, Ajioka J, Van Voorhis WC. Trypanosoma cruzi: expression of interleukin-2 utilizing both supercoiled plasmids and linear DNAs. Exp Parasitol. 1996  ;83(1):159-63.

Centurion-Lara A, Castro C, Van Voorhis WC, Lukehart SA. Two 16S-23S ribosomal DNA intergenic regions in different Treponema pallidum subspecies contain tRNA genes. FEMS Microbiol Lett. 1996  ;143(2-3):235-40.

Guiney DG, Fang FC, Krause M, Libby S, Buchmeier NA, Fierer J. Biology and clinical significance of virulence plasmids in Salmonella serovars. Clin Infect Dis. 1995  ;21 Suppl 2:S146-51.

Chen CY, Buchmeier NA, Libby S, Fang FC, Krause M, Guiney DG. Central regulatory role for the RpoS sigma factor in expression of Salmonella dublin plasmid virulence genes. J Bacteriol. 1995  ;177(18):5303-9.

Marra CM, Critchlow CW, Hook EW, Collier AC, Lukehart SA. Cerebrospinal fluid treponemal antibodies in untreated early syphilis. Arch Neurol. 1995  ;52(1):68-72.

Moolenaar RL, Dalton C, Lipman HB, Umland ET, Gallaher M, Duchin JS, Chapman L, Zaki SR, Ksiazek TG, Rollin PE. Clinical features that differentiate hantavirus pulmonary syndrome from three other acute respiratory illnesses. Clin Infect Dis. 1995  ;21(3):643-9.

Liles WC, Ledbetter JA, Waltersdorph AW, Klebanoff SJ. Cross-linking of CD18 primes human neutrophils for activation of the respiratory burst in response to specific stimuli: implications for adhesion-dependent physiological responses in neutrophils. J Leukoc Biol. 1995  ;58(6):690-7.

Liles WC, Ledbetter JA, Waltersdorph AW, Klebanoff SJ. Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes. J Immunol. 1995  ;155(4):2175-84.

Buchmeier NA, Libby SJ, Xu Y, Loewen PC, Switala J, Guiney DG, Fang FC. DNA repair is more important than catalase for Salmonella virulence in mice. J Clin Invest. 1995  ;95(3):1047-53.

La Flamme AC, Buckner FS, Swindle J, Ajioka J, Van Voorhis WC. Expression of mammalian cytokines by Trypanosoma cruzi indicates unique signal sequence requirements and processing. Mol Biochem Parasitol. 1995  ;75(1):25-31.

Liles WC, Dale DC, Klebanoff SJ. Glucocorticoids inhibit apoptosis of human neutrophils. Blood. 1995  ;86(8):3181-8.

Guiney DG, Libby S, Fang FC, Krause M, Fierer J. Growth-phase regulation of plasmid virulence genes in Salmonella. Trends Microbiol. 1995  ;3(7):275-9.

Duchin JS, Breiman RF, Diamond A, Lipman HB, Block SL, Hedrick JA, Finger R, Elliott JA. High prevalence of multidrug-resistant Streptococcus pneumoniae among children in a rural Kentucky community. Pediatr Infect Dis J. 1995  ;14(9):745-50.

Berggren RE, Wunderlich A, Ziegler E, Schleicher M, Duke RC, Looney D, Fang FC. HIV gp120-specific cell-mediated immune responses in mice after oral immunization with recombinant Salmonella. J Acquir Immune Defic Syndr Hum Retrovirol. 1995  ;10(5):489-95.

Lukehart SA. Modern syphilis--still a shadow on the land. West J Med. 1995  ;163(6):587-8.

Murphy SC, Lowitt MH, Kao GF. Multiple eruptive dermatofibromas in an HIV-positive man. Dermatology. 1995  ;190(4):309-12.

Krause M, Fang FC, el-Gedaily A, Libby S, Guiney DG. Mutational analysis of SpvR binding to DNA in the regulation of the Salmonella plasmid virulence operon. Plasmid. 1995  ;34(1):37-47.

Liles WC, Klebanoff SJ. Regulation of apoptosis in neutrophils--Fas track to death?. J Immunol. 1995  ;155(7):3289-91.

Dale DC, Liles WC, Summer WR, Nelson S. Review: granulocyte colony-stimulating factor--role and relationships in infectious diseases. J Infect Dis. 1995  ;172(4):1061-75.

Liles WC, Van Voorhis WC. Review: nomenclature and biologic significance of cytokines involved in inflammation and the host immune response. J Infect Dis. 1995  ;172(6):1573-80.

Prince RW, Xu Y, Libby SJ, Fang FC. Cloning and sequencing of the gene encoding the RpoS (KatF) sigma factor from Salmonella typhimurium 14028s. Biochim Biophys Acta. 1994  ;1219(1):198-200.

Libby SJ, Goebel W, Ludwig A, Buchmeier N, Bowe F, Fang FC, Guiney DG, Songer JG, Heffron F. A cytolysin encoded by Salmonella is required for survival within macrophages. Proc Natl Acad Sci U S A. 1994  ;91(2):489-93.

Okada AA, Johnson RP, Liles WC, D'Amico DJ, Baker AS. Endogenous bacterial endophthalmitis. Report of a ten-year retrospective study. Ophthalmology. 1994  ;101(5):832-8.

La Flamme AC, Buckner F, Swindle J, Ajioka J, Barrett L, Van Voorhis WC. Engineering cytokine secretion from Trypanosoma cruzi. Mem Inst Oswaldo Cruz. 1994  ;89(4):650-1.

Hirschmann JV, Patterson S, Drachman JG, Rosen H, Liles WC. Increased erythrocyte sedimentation rate and a splenic mass. West J Med. 1994  ;161(6):585-91.

Guiney DG, Fang FC, Krause M, Libby S. Plasmid-mediated virulence genes in non-typhoid Salmonella serovars. FEMS Microbiol Lett. 1994  ;124(1):1-9.

McGuire TC, Stephens EB, Palmer GH, McElwain TF, Lichtensteiger CA, Leib SR, Barbet AF. Recombinant vaccinia virus expression of Anaplasma marginale surface protein MSP-1a: effect of promoters, leader sequences and GPI anchor sequence on antibody response. Vaccine. 1994  ;12(5):465-71.

Gordon SM, Eaton ME, George R, Larsen S, Lukehart SA, Kuypers J, Marra CM, Thompson S. The response of symptomatic neurosyphilis to high-dose intravenous penicillin G in patients with human immunodeficiency virus infection. N Engl J Med. 1994  ;331(22):1469-73.

O'Neal CR, Gabriel WM, Turk AK, Libby SJ, Fang FC, Spector MP. RpoS is necessary for both the positive and negative regulation of starvation survival genes during phosphate, carbon, and nitrogen starvation in Salmonella typhimurium. J Bacteriol. 1994  ;176(15):4610-6.

Park DR, Liles WC, Kirby P. Severe atypical Behçet's syndrome. West J Med. 1994  ;160(1):60-3.

Long NC, Frevert CW, Shore SA. Capsaicin pretreatment increases inflammatory response to intratracheal instillation of endotoxin in rats. Regul Pept. 1993  ;46(1-2):208-10.

Baker-Zander SA, Shaffer JM, Lukehart SA. Characterization of the serum requirement for macrophage-mediated killing of Treponema pallidum ssp. pallidum: relationship to the development of opsonizing antibodies. FEMS Immunol Med Microbiol. 1993  ;6(4):273-9.

Rose TM, Lagrou MJ, Fransson I, Werelius B, Delattre O, Thomas G, de Jong PJ, Todaro GJ, Dumanski JP. The genes for oncostatin M (OSM) and leukemia inhibitory factor (LIF) are tightly linked on human chromosome 22. Genomics. 1993  ;17(1):136-40.

Liles WC, Spach DH. Late relapse of tick-borne relapsing fever following treatment with doxycycline. West J Med. 1993  ;158(2):200.

Shaffer JM, Baker-Zander SA, Lukehart SA. Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes. Infect Immun. 1993  ;61(2):781-4.

Moncó JCGarcía, Wheeler CM, Benach JL, Furie RA, Lukehart SA, Stanek G, Steere AC. Reactivity of neuroborreliosis patients (Lyme disease) to cardiolipin and gangliosides. J Neurol Sci. 1993  ;117(1-2):206-14.

Liles WC, Cushing H, Holt S, Bryan C, Hackman RC. Severe adenoviral nephritis following bone marrow transplantation: successful treatment with intravenous ribavirin. Bone Marrow Transplant. 1993  ;12(4):409-12.

Spach DH, Liles WC, Campbell GL, Quick RE, Anderson DE, Fritsche TR. Tick-borne diseases in the United States. N Engl J Med. 1993  ;329(13):936-47.

Liles WC, Burger RJ. Tularemia from domestic cats. West J Med. 1993  ;158(6):619-22.

Baker-Zander SA, Shaffer JM, Lukehart SA. VDRL antibodies enhance phagocytosis of Treponema pallidum by macrophages. J Infect Dis. 1993  ;167(5):1100-5.

Marra CM, Handsfield HH, Kuller L, Morton WR, Lukehart SA. Alterations in the course of experimental syphilis associated with concurrent simian immunodeficiency virus infection. J Infect Dis. 1992  ;165(6):1020-5.

Fang FC, Libby SJ, Buchmeier NA, Loewen PC, Switala J, Harwood J, Guiney DG. The alternative sigma factor katF (rpoS) regulates Salmonella virulence. Proc Natl Acad Sci U S A. 1992  ;89(24):11978-82.

Koelle DM, Benedetti J, Langenberg A, Corey L. Asymptomatic reactivation of herpes simplex virus in women after the first episode of genital herpes. Ann Intern Med. 1992  ;116(6):433-7.

Klebanoff SJ, Olszowski S, Van Voorhis WC, Ledbetter JA, Waltersdorph AM, Schlechte KG. Effects of gamma-interferon on human neutrophils: protection from deterioration on storage. Blood. 1992  ;80(1):225-34.

Marra CM, Slatter V, Tartaglione TA, Baker-Zander SA, Lukehart SA. Evaluation of aqueous penicillin G and ceftriaxone for experimental neurosyphilis. J Infect Dis. 1992  ;165(2):396-7.

Baker-Zander SA, Lukehart SA. Macrophage-mediated killing of opsonized Treponema pallidum. J Infect Dis. 1992  ;165(1):69-74.

Bruce AG, Linsley PS, Rose TM. Oncostatin M. Prog Growth Factor Res. 1992  ;4(2):157-70.

Riviere GR, Elliot KS, Adams DF, Simonson LG, Forgas LB, Nilius AM, Lukehart SA. Relative proportions of pathogen-related oral spirochetes (PROS) and Treponema denticola in supragingival and subgingival plaque from patients with periodontitis. J Periodontol. 1992  ;63(2):131-6.

Lukehart SA, Shaffer JM, Baker-Zander SA. A subpopulation of Treponema pallidum is resistant to phagocytosis: possible mechanism of persistence. J Infect Dis. 1992  ;166(6):1449-53.

Marra C, Baker-Zander SA, Hook EW, Lukehart SA. An experimental model of early central nervous system syphilis. J Infect Dis. 1991  ;163(4):825-9.

Riviere GR, Wagoner MA, Baker-Zander SA, Weisz KS, Adams DF, Simonson L, Lukehart SA. Identification of spirochetes related to Treponema pallidum in necrotizing ulcerative gingivitis and chronic periodontitis. N Engl J Med. 1991  ;325(8):539-43.

Schwebke JR, Lukehart SA, Roberts MC, Hillier SL. Identification of two new antigenic subgroups within the genus Mobiluncus. J Clin Microbiol. 1991  ;29(10):2204-8.

Riviere GR, Weisz KS, Simonson LG, Lukehart SA. Pathogen-related spirochetes identified within gingival tissue from patients with acute necrotizing ulcerative gingivitis. Infect Immun. 1991  ;59(8):2653-7.

Burstain JM, Grimprel E, Lukehart SA, Norgard MV, Radolf JD. Sensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol. 1991  ;29(1):62-9.

Lukehart SA. Serologic testing after therapy for syphilis: is there a test for cure?. Ann Intern Med. 1991  ;114(12):1057-8.

Barron SL, Riviere GR, Simonson LG, Lukehart SA, Tira DE, O'Neil DW. Use of monoclonal antibodies to enumerate spirochetes and identify Treponema denticola in dental plaque of children, adolescents and young adults. Oral Microbiol Immunol. 1991  ;6(2):97-101.

Schwebke JR, Hillier SL, Fohn MJ, Lukehart SA. Demonstration of heterogeneity among the antigenic proteins of Mobiluncus species. J Clin Microbiol. 1990  ;28(3):463-8.

Lukehart SA, Fohn MJ, Baker-Zander SA. Efficacy of azithromycin for therapy of active syphilis in the rabbit model. J Antimicrob Chemother. 1990  ;25 Suppl A:91-9.

Allred DR, McGuire TC, Palmer GH, Leib SR, Harkins TM, McElwain TF, Barbet AF. Molecular basis for surface antigen size polymorphisms and conservation of a neutralization-sensitive epitope in Anaplasma marginale. Proc Natl Acad Sci U S A. 1990  ;87(8):3220-4.

Baker-Zander SA, Lukehart SA. Efficacy of cefmetazole in the treatment of active syphilis in the rabbit model. Antimicrob Agents Chemother. 1989  ;33(9):1465-9.

Isaacs RD, Hanke JH, Guzman-Verduzco LM, Newport G, Agabian N, Norgard MV, Lukehart SA, Radolf JD. Molecular cloning and DNA sequence analysis of the 37-kilodalton endoflagellar sheath protein gene of Treponema pallidum. Infect Immun. 1989  ;57(11):3403-11.

Liles WC, Nathanson NM. Alteration in the regulation of neuronal muscarinic acetylcholine receptor number induced by chronic lithium in neuroblastoma cells. Brain Res. 1988  ;439(1-2):88-94.

Subers EM, Liles WC, Luetje CW, Nathanson NM. Biochemical and immunological studies on the regulation of cardiac and neuronal muscarinic acetylcholine receptor number and function. Trends Pharmacol Sci. 1988  ;Suppl:25-8.

Baker-Zander SA, Fohn MJ, Lukehart SA. Development of cellular immunity to individual soluble antigens of Treponema pallidum during experimental syphilis. J Immunol. 1988  ;141(12):4363-9.

Greenblatt RM, Lukehart SA, Plummer FA, Quinn TC, Critchlow CW, Ashley RL, D'Costa LJ, Ndinya-Achola JO, Corey L, Ronald AR. Genital ulceration as a risk factor for human immunodeficiency virus infection. AIDS. 1988  ;2(1):47-50.

Lukehart SA, Hook EW, Baker-Zander SA, Collier AC, Critchlow CW, Handsfield HH. Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment. Ann Intern Med. 1988  ;109(11):855-62.

Martin JM, Liles WC, Nathanson NM. Modification of neuronal muscarinic receptor-mediated responses by islet-activating protein. Brain Res. 1988  ;455(2):370-6.

Fohn MJ, Lukehart SA, Hillier SL. Production and characterization of monoclonal antibodies to Mobiluncus species. J Clin Microbiol. 1988  ;26(12):2598-603.

Fohn MJ, Wignall S, Baker-Zander SA, Lukehart SA. Specificity of antibodies from patients with pinta for antigens of Treponema pallidum subspecies pallidum. J Infect Dis. 1988  ;157(1):32-7.

Webb NR, Rose TM, Malik N, Marquardt H, Shoyab M, Todaro GJ, Lee DC. Bovine and human cDNA sequences encoding a putative benzodiazepine receptor ligand. DNA. 1987  ;6(1):71-9.

Berry CD, Hooton TM, Collier AC, Lukehart SA. Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection. N Engl J Med. 1987  ;316(25):1587-9.

Liles WC, Meier KE, Henderson WR. Phorbol myristate acetate and the calcium ionophore A23187 synergistically induce release of LTB4 by human neutrophils: involvement of protein kinase C activation in regulation of the 5-lipoxygenase pathway. J Immunol. 1987  ;138(10):3396-402.

Liles WC, Nathanson NM. Regulation of muscarinic acetylcholine receptor number in cultured neuronal cells by chronic membrane depolarization. J Neurosci. 1987  ;7(8):2556-63.

Lukehart SA, Baker-Zander SA. Roxithromycin (RU 965): effective therapy for experimental syphilis infection in rabbits. Antimicrob Agents Chemother. 1987  ;31(2):187-90.

Torian BE, Lukehart SA, Stamm WE. Use of monoclonal antibodies to identify, characterize, and purify a 96,000-dalton surface antigen of pathogenic Entamoeba histolytica. J Infect Dis. 1987  ;156(2):334-43.

Liles WC, Hunter DD, Meier KE, Nathanson NM. Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells. J Biol Chem. 1986  ;261(12):5307-13.

Hook EW, Baker-Zander SA, Moskovitz BL, Lukehart SA, Handsfield HH. Ceftriaxone therapy for asymptomatic neurosyphilis. Case report and Western blot analysis of serum and cerebrospinal fluid IgG response to therapy. Sex Transm Dis. 1986  ;13(3 Suppl):185-8.

Lukehart SA, Baker-Zander SA, Sell S. Characterization of the humoral immune response of the rabbit to antigens of Treponema pallidum after experimental infection and therapy. Sex Transm Dis. 1986  ;13(1):9-15.

Liles WC, Taylor S, Finnell R, Lai H, Nathanson NM. Decreased muscarinic acetylcholine receptor number in the central nervous system of the tottering (tg/tg) mouse. J Neurochem. 1986  ;46(3):977-82.

Lukehart SA. Future application of research tests to the diagnosis of yaws and other endemic treponematoses. Southeast Asian J Trop Med Public Health. 1986  ;17(4 Suppl):78-83.

Baker-Zander SA, Roddy RE, Handsfield HH, Lukehart SA. IgG and IgM antibody reactivity to antigens of Treponema pallidum after treatment of syphilis. Sex Transm Dis. 1986  ;13(4):214-20.

Liles WC, Nathanson NM. Regulation of neuronal muscarinic acetylcholine receptor number by protein glycosylation. J Neurochem. 1986  ;46(1):89-95.

Lawrence K, Palmer GH, Needham JR. Use of carbenicillin in two species of tortoise (Testudo graeca and T hermanni). Res Vet Sci. 1986  ;40(3):413-5.

Baker-Zander SA, Hook EW, Bonin P, Handsfield HH, Lukehart SA. Antigens of Treponema pallidum recognized by IgG and IgM antibodies during syphilis in humans. J Infect Dis. 1985  ;151(2):264-72.

Lukehart SA, Tam MR, Hom J, Baker-Zander SA, Holmes KK, Nowinski RC. Characterization of monoclonal antibodies to Treponema pallidum. J Immunol. 1985  ;134(1):585-92.

DiGiacomo RF, Lukehart SA, Talburt CD, Baker-Zander SA, Giddens WE, Condon J, Brown CW. Chronicity of infection with Treponema paraluis-cuniculi in New Zealand white rabbits. Genitourin Med. 1985  ;61(3):156-64.

Lee DC, Rose TM, Webb NR, Todaro GJ. Cloning and sequence analysis of a cDNA for rat transforming growth factor-alpha. Nature. 1985  ;313(6002):489-91.

Hook EW, Roddy RE, Lukehart SA, Hom J, Holmes KK, Tam MR. Detection of Treponema pallidum in lesion exudate with a pathogen-specific monoclonal antibody. J Clin Microbiol. 1985  ;22(2):241-4.

Lukehart SA. Prospects for development of a treponemal vaccine. Rev Infect Dis. 1985  ;7 Suppl 2:S305-13.

Baker-Zander SA, Lukehart SA. Antigenic cross-reactivity between Treponema pallidum and other pathogenic members of the family Spirochaetaceae. Infect Immun. 1984  ;46(1):116-21.

DiGiacomo RF, Lukehart SA, Talburt CD, Baker-Zander SA, Condon J, Brown CW. Clinical course and treatment of venereal spirochaetosis in New Zealand white rabbits. Br J Vener Dis. 1984  ;60(4):214-8.

Lukehart SA, Baker-Zander SA, Holmes KK. Efficacy of aztreonam in treatment of experimental syphilis in rabbits. Antimicrob Agents Chemother. 1984  ;25(3):390-1.

Gamboa D, Miller JN, Lukehart SA, Baker-Zander SA, Sell S. Experimental neonatal syphilis. II. Immunological responses of neonatal rabbits to intradermal inoculation with Treponema pallidum (Nichols strain). Pediatr Res. 1984  ;18(10):972-9.

Lawrence K, Needham JR, Palmer GH, Lewis JC. A preliminary study on the use of carbenicillin in snakes. J Vet Pharmacol Ther. 1984  ;7(2):119-24.

Handsfield HH, Lukehart SA. Prevention of congenital syphilis. JAMA. 1984  ;252(13):1750-1.

Roddy R, Lukehart SA, Handsfield HH. Acyclovir ointment does not affect the dark-field examination in primary syphilis. Sex Transm Dis. 1983  ;10(4):198-9.

Handsfield HH, Lukehart SA, Sell S, Norris SJ, Holmes KK. Demonstration of Treponema pallidum in a cutaneous gumma by indirect immunofluorescence. Arch Dermatol. 1983  ;119(8):677-80.

Baker-Zander SA, Lukehart SA. Molecular basis of immunological cross-reactivity between Treponema pallidum and Treponema pertenue. Infect Immun. 1983  ;42(2):634-8.

Van Voorhis WC, Valinsky J, Hoffman E, Luban J, Hair LS, Steinman RM. Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication. J Exp Med. 1983  ;158(1):174-91.

Van Voorhis WC, Steinman RM, Hair LS, Luban J, Witmer MD, Koide S, Cohn ZA. Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages. J Exp Med. 1983  ;158(1):126-45.

DiGiacomo RF, Talburt CD, Lukehart SA, Baker-Zander SA, Condon J. Treponema paraluis-cuniculi infection in a commercial rabbitry: epidemiology and serodiagnosis. Lab Anim Sci. 1983  ;33(6):562-6.

Lukehart SA. Activation of macrophages by products of lymphocytes from normal and syphilitic rabbits. Infect Immun. 1982  ;37(1):64-9.

Van Voorhis WC, Kaplan G, Sarno EN, Horwitz MA, Steinman RM, Levis WR, Nogueira N, Hair LS, Gattass CR, Arrick BA, et al. The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes. N Engl J Med. 1982  ;307(26):1593-7.

Lukehart SA, Baker-Zander SA, Gubish ER. Identification of Treponema pallidum antigens: comparison with a nonpathogenic treponeme. J Immunol. 1982  ;129(2):833-8.

Bayly WM, Reed SM, Leathers CW, Brown CM, Traub JL, Paradis MR, Palmer GH. Multiple congenital heart anomalies in five Arabian foals. J Am Vet Med Assoc. 1982  ;181(7):684-9.

Quinn TC, Lukehart SA, Goodell S, Mkrtichian E, Schuffler MD, Holmes KK. Rectal mass caused by Treponema pallidum: confirmation by immunofluorescent staining. Gastroenterology. 1982  ;82(1):135-9.

Baker-Zander SA, Sell S, Lukehart SA. Serum regulation of in vitro lymphocyte responses in early experimental syphilis. Infect Immun. 1982  ;37(2):568-78.

Lukehart SA, Baker-Zander SA, Lloyd RM, Sell S. Effect of cortisone administration on host-parasite relationships in early experimental syphilis. J Immunol. 1981  ;127(4):1361-8.

Lukehart SA, Baker-Zander SA, Lloyd RM, Sell S. Characterization of lymphocyte responsiveness in early experimental syphilis. II. Nature of cellular infiltration and Treponema pallidum distribution in testicular lesions. J Immunol. 1980  ;124(1):461-7.

Lukehart SA, Baker-Zander SA, Sell S. Characterization of lymphocyte responsiveness in early experimental syphilis. I. In vitro response to mitogens and Treponema pallidum antigens. J Immunol. 1980  ;124(1):454-60.

Sell S, Gamboa D, Baker-Zander SA, Lukehart SA, Miller JN. Host response to Treponema pallidum in intradermally-infected rabbits: evidence for persistence of infection at local and distant sites. J Invest Dermatol. 1980  ;75(6):470-5.

Lukehart SA, Miller JN. Demonstration of the in vitro phagocytosis of Treponema pallidum by rabbit peritoneal macrophages. J Immunol. 1978  ;121(5):2014-24.

Lehrer SB, Rose TM, Vaughan JH. Induction and yield of reaginic antibodies in mouse serum and ascitic fluid. Immunology. 1976  ;30(1):107-15.