Title: Biblio RTF Export
Author: Biblio 7.x

Giacani L, Iverson-Cabral SL, King JCK, Molini BJ, Lukehart SA, Centurion-Lara A. Complete Genome Sequence of the Treponema pallidum subsp. pallidum Sea81-4 Strain. Genome Announc. 2014  ;2(2).

Giacani L, Lukehart SA. The endemic treponematoses. Clin Microbiol Rev. 2014  ;27(1):89-115.

Murphy SC, Hermsen CC, Douglas AD, Edwards NJ, Petersen I, Fahle GA, Adams M, Berry AA, Billman ZP, Gilbert SC, et al. External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance. PLoS One. 2014  ;9(5):e97398.

Kim H, Erdman LK, Lu Z, Serghides L, Zhong K, Dhabangi A, Musoke C, Gerard C, Cserti-Gazdewich C, Liles CW, et al. Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria. Infect Immun. 2014  ;82(1):371-9.

Conroy AL, Gélvez M, Hawkes M, Rajwans N, Liles CW, Villar-Centeno LA, Kain KC. Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study. BMC Infect Dis. 2014  ;14:35.

Rustagi A, Gale M. Innate antiviral immune signaling, viral evasion and modulation by HIV-1. J Mol Biol. 2014  ;426(6):1161-77.

Garrigues JH, Rubinchikova YE, Rose TM. KSHV cell attachment sites revealed by ultra sensitive tyramide signal amplification (TSA) localize to membrane microdomains that are up-regulated on mitotic cells. Virology. 2014  ;452-453:75-85.

Chapuis AG, Afanasiev OK, Iyer JG, Paulson KG, Parvathaneni U, Hwang JH, Lai I, Roberts IM, Sloan HL, Bhatia S, et al. Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I. Cancer Immunol Res. 2014  ;2(1):27-36.

Tatipaka HB, Gillespie RJ, Chatterjee AK, Norcross NR, Hulverson MA, Ranade RM, Nagendar P, Creason SA, McQueen J, Duster NA, et al. Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis. J Med Chem. 2014  ;57(3):828-35.

Wollish AC, Ferris MT, Blevins LK, Loo Y-M, Gale M, Heise MT. An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo. Virology. 2013  ;435(2):269-80.

Ma DY, Suthar MS, Kasahara S, Gale M, Clark EA. CD22 is required for protection against West Nile virus Infection. J Virol. 2013  ;87(6):3361-75.

Gottlieb GS. Changing HIV epidemics: what HIV-2 can teach us about ending HIV-1. AIDS. 2013  ;27(1):135-7.

Ekouevi DK, Balestre E, Coffie PA, Minta D, Messou E, Sawadogo A, Minga A, Sow PSalif, Bissagnene E, Eholie SP, et al. Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study. PLoS One. 2013  ;8(6):e66135.

Dittrich T, Macor L, Gervaldo M, Fungo F, Otero L, Lin CY, Chi LC, Fang FC, Lii SW, Wong KT, et al. Charge separation in donor-acceptor spiro compounds at metal and metal oxide surfaces investigated by surface photovoltage. J Nanosci Nanotechnol. 2013  ;13(7):5158-63.

Graham SM, Mwilu R, W Liles C. Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: A systematic review. Virulence. 2013  ;4(6):564-71.

Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, et al. Combining functional and structural genomics to sample the essential Burkholderia structome. PLoS One. 2013  ;8(1):e53851.

Raugi DN, Smith RA, Ba S, Toure M, Traore F, Sall F, Pan C, Blankenship L, Montano A, Olson J, et al. Complex patterns of protease inhibitor resistance among antiretroviral treatment-experienced HIV-2 patients from Senegal: implications for second-line therapy. Antimicrob Agents Chemother. 2013  ;57(6):2751-60.

Weiss DJ, Bates JHt, Gilbert T, W Liles C, Lutzko C, Rajagopal J, Prockop DJ. Conference Report: Stem Cells and Cell Therapies in Lung Biology and Diseases University of Vermont, July 2011. Ann Am Thorac Soc. 2013  .

Suryadevara PK, Racherla KK, Olepu S, Norcross NR, Tatipaka HB, Arif JA, Planer JD, Lepesheva GI, Verlinde CLMJ, Buckner FS, et al. Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14?-demethylase as anti-Chagas disease agents. Bioorg Med Chem Lett. 2013  ;23(23):6492-9.

Cho H, Proll SC, Szretter KJ, Katze MG, Gale M, Diamond MS. Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Nat Med. 2013  ;19(4):458-64.

Graham SM, Rajwans N, Jaoko W, Estambale BBA, R McClelland S, Overbaugh J, W Liles C. Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression. AIDS. 2013  ;27(11):1803-13.

Zinn RL, Gardner EE, Marchionni L, Murphy SC, Dobromilskaya I, Hann CL, Rudin CM. ERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer. Mol Cancer Ther. 2013  ;12(6):1131-9.

Errett JS, Suthar MS, McMillan A, Diamond MS, Gale M. The Essential, Nonredundant Roles of RIG-I and MDA5 in Detecting and Controlling West Nile Virus Infection. J Virol. 2013  ;87(21):11416-11425.

Centurion-Lara A, Giacani L, Godornes C, Molini BJ, Brinck Reid T, Lukehart SA. Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains. PLoS Negl Trop Dis. 2013  ;7(5):e2222.

Woodland A, Grimaldi R, Luksch T, Cleghorn LAT, Ojo KK, Van Voorhis WC, Brenk R, Frearson JA, Gilbert IH, Wyatt PG. From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules. ChemMedChem. 2013  ;8(7):1127-37.

Stone AEL, Giugliano S, Schnell G, Cheng L, Leahy KF, Golden-Mason L, Gale M, Rosen HR. Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells. PLoS Pathog. 2013  ;9(4):e1003316.

Raugi DN, Gottlieb GS, Sow PS, Toure M, Sall F, Gaye A, N'doye I, Kiviat NB, Hawes SE. HIV-1 outcompetes HIV-2 in dually infected Senegalese individuals with low CD4+ cell counts. AIDS. 2013  ;27(15):2441-2450.

Wilkins C, Woodward J, Lau DT-Y, Barnes A, Joyce M, McFarlane N, McKeating JA, D Tyrrell L, Gale M. IFITM1 is a tight junction protein that inhibits hepatitis C virus entry. Hepatology. 2013  ;57(2):461-9.

Negash AA, Ramos HJ, Crochet N, T Y Lau D, Doehle B, Papic N, Delker DA, Jo J, Bertoletti A, Hagedorn CH, et al. IL-1? production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease. PLoS Pathog. 2013  ;9(4):e1003330.

Lai Y, Altemeier WA, Vandree J, Piliponsky AM, Johnson B, Appel CL, Frevert CW, Hyde DM, Ziegler SF, Smith DE, et al. Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33. J Allergy Clin Immunol. 2013  .

Ranade RM, Gillespie RJ, Shibata S, Verlinde CLMJ, Fan E, Hol WGJ, Buckner FS. Induced resistance to methionyl-tRNA synthetase inhibitors in Trypanosoma brucei is due to overexpression of the target. Antimicrob Agents Chemother. 2013  ;57(7):3021-8.

Kumar M, Roe K, Orillo B, Muruve DA, Nerurkar VR, Gale M, Verma S. Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis. J Virol. 2013  ;87(7):3655-67.

Mateo R, Nagamine CM, Spagnolo J, Méndez E, Rahe M, Gale M, Yuan J, Kirkegaard K. Inhibition of cellular autophagy deranges dengue virion maturation. J Virol. 2013  ;87(3):1312-21.

Burns TF, Dobromilskaya I, Murphy SC, Gajula RP, Thiyagarajan S, Chatley SNH, Aziz K, Cho Y-J, Tran PT, Rudin CM. Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer. Mol Cancer Res. 2013  ;11(4):329-38.

Lau DT-Y, Negash A, Chen J, Crochet N, Sinha M, Zhang Y, Guedj J, Holder S, Saito T, Lemon SM, et al. Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection. Gastroenterology. 2013  ;144(2):402-413.e12.

Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, Vick SC, Clepper L, Thackray L, Brassil MM, Virgin HW, et al. IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog. 2013  ;9(1):e1003118.

A Bruce G, Ryan JT, Thomas MJ, Peng X, Grundhoff A, Tsai C-C, Rose TM. Next-Generation Sequence Analysis of the Genome of RFHVMn, the Macaque Homolog of Kaposi's Sarcoma (KS)-Associated Herpesvirus, from a KS-Like Tumor of a Pig-Tailed Macaque. J Virol. 2013  ;87(24):13676-93.

Lazear HM, Pinto AK, Ramos HJ, Vick SC, Shrestha B, Suthar MS, Gale M, Diamond MS. Pattern Recognition Receptor MDA5 Modulates CD8+ T Cell-Dependent Clearance of West Nile Virus from the Central Nervous System. J Virol. 2013  ;87(21):11401-11415.

Vu H, Roullier C, Campitelli M, Trenholme KR, Gardiner DL, Andrews KT, Skinner-Adams T, Crowther GJ, Van Voorhis WC, Quinn RJ. Plasmodium Gametocyte Inhibition Identified from a Natural-Product-Based Fragment Library. ACS Chem Biol. 2013  .

Tchesnokova V, Billig M, Chattopadhyay S, Linardopoulou E, Aprikian P, Roberts PL, Skrivankova V, Johnston B, Gileva A, Igusheva I, et al. Predictive diagnostics for Escherichia coli infections based on the clonal association of antimicrobial resistance and clinical outcome. J Clin Microbiol. 2013  ;51(9):2991-9.

Graham SM, Rajwans N, Tapia KA, Jaoko W, Estambale BBa, R McClelland S, Overbaugh J, W Liles C. A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy. BMC Infect Dis. 2013  ;13(1):263.

G Hammac K, Ku P-S, Galletti MF, Noh SM, Scoles GA, Palmer GH, Brayton KA. Protective immunity induced by immunization with a live, cultured Anaplasma marginale strain. Vaccine. 2013  ;31(35):3617-22.

Hallstrand TS, Lai Y, Altemeier WA, Appel CL, Johnson B, Frevert CW, Hudkins KL, Bollinger JG, Woodruff PG, Hyde DM, et al. Regulation and function of epithelial secreted phospholipase A2 group X in asthma. Am J Respir Crit Care Med. 2013  ;188(1):42-50.

Horner SM, Gale M. Regulation of hepatic innate immunity by hepatitis C virus. Nat Med. 2013  ;19(7):879-88.

Ermler ME, Yerukhim E, Schriewer J, Schattgen S, Traylor Z, Wespiser AR, Caffrey DR, Chen ZJ, King CH, Gale M, et al. RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge. J Virol. 2013  ;87(9):4846-60.

Li J, Ding SC, Cho H, Chung BC, Gale M, Chanda SK, Diamond MS. A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response. MBio. 2013  ;4(3):e00385-13.

Wilkins C, Gale M. Sterol-izing innate immunity. Immunity. 2013  ;38(1):3-5.

Ireton RC, Gale M. Systems biology analyses to define host responses to HCV infection and therapy. Curr Top Microbiol Immunol. 2013  ;363:143-67.

Suthar MS, Brassil MM, Blahnik G, McMillan A, Ramos HJ, Proll SC, Belisle SE, Katze MG, Gale M. A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes. PLoS Pathog. 2013  ;9(2):e1003168.

Rustagi A, Doehle BP, McElrath JM, Gale M. Two new monoclonal antibodies for biochemical and flow cytometric analyses of human interferon regulatory factor-3 activation, turnover, and depletion. Methods. 2013  ;59(2):225-32.

Suthar MS, Diamond MS, Gale M. West Nile virus infection and immunity. Nat Rev Microbiol. 2013  ;11(2):115-28.

Szretter KJ, Daniels BP, Cho H, Gainey MD, Yokoyama WM, Gale M, Virgin HW, Klein RS, Sen GC, Diamond MS. 2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. PLoS Pathog. 2012  ;8(5):e1002698.

Gall A, Treuting P, Elkon KB, Loo Y-M, Gale M, Barber GN, Stetson DB. Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity. 2012  ;36(1):120-31.

Zhang Z, Ojo KK, Johnson SM, Larson ET, He P, Geiger JA, Castellanos-Gonzalez A, White CA, Parsons M, Merritt EA, et al. Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1. Bioorg Med Chem Lett. 2012  ;22(16):5264-7.

Kong R, Li H, Bibollet-Ruche F, Decker JM, Zheng NN, Gottlieb GS, Kiviat NB, Sow PSalif, Georgiev I, Hahn BH, et al. Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection. J Virol. 2012  ;86(2):947-60.

Pagán AJ, Pepper M, H Chu H, Green JM, Jenkins MK. CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs. J Immunol. 2012  ;189(6):2909-17.

Diamond MS, Gale M. Cell-intrinsic innate immune control of West Nile virus infection. Trends Immunol. 2012  ;33(10):522-30.

Giacani L, Brandt SL, Puray-Chavez M, Reid TBrinck, Godornes C, Molini BJ, Benzler M, Hartig JS, Lukehart SA, Centurion-Lara A. Comparative investigation of the genomic regions involved in antigenic variation of the TprK antigen among treponemal species, subspecies, and strains. J Bacteriol. 2012  ;194(16):4208-25.

Horner SM, Park HSoo, Gale M. Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix ?0. J Virol. 2012  ;86(6):3112-20.

Patel MR, Loo Y-M, Horner SM, Gale M, Malik HS. Convergent evolution of escape from hepaciviral antagonism in primates. PLoS Biol. 2012  ;10(3):e1001282.

Petruzziello-Pellegrini TN, Yuen DA, Page AV, Patel S, Soltyk AM, Matouk CC, Wong DK, Turgeon PJ, Fish JE, Ho JJDavid, et al. The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest. 2012  ;122(2):759-76.

Johnson SM, Murphy RC, Geiger JA, DeRocher AE, Zhang Z, Ojo KK, Larson ET, Perera GBK, Dale EJ, He P, et al. Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity. J Med Chem. 2012  ;55(5):2416-26.

Koh CY, Kim JE, Shibata S, Ranade RM, Yu M, Liu J, Gillespie RJ, Buckner FS, Verlinde CLMJ, Fan E, et al. Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection. Structure. 2012  ;20(10):1681-91.

Benecke A, Gale M, Katze MG. Dynamics of innate immunity are key to chronic immune activation in AIDS. Curr Opin HIV AIDS. 2012  ;7(1):79-85.

Kisiela DI, Chattopadhyay S, Libby SJ, Karlinsey JE, Fang FC, Tchesnokova V, Kramer JJ, Beskhlebnaya V, Samadpour M, Grzymajlo K, et al. Evolution of Salmonella enterica virulence via point mutations in the fimbrial adhesin. PLoS Pathog. 2012  ;8(6):e1002733.

Ueti MW, Tan Y, Broschat SL, Ortiz EJCastañe, Camacho-Nuez M, Mosqueda JJ, Scoles GA, Grimes M, Brayton KA, Palmer GH. Expansion of variant diversity associated with a high prevalence of pathogen strain superinfection under conditions of natural transmission. Infect Immun. 2012  ;80(7):2354-60.

Giacani L, Chattopadhyay S, Centurion-Lara A, Jeffrey BM, Le HT, Molini BJ, Lukehart SA, Sokurenko EV, Rockey DD. Footprint of positive selection in Treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen. PLoS Negl Trop Dis. 2012  ;6(6):e1698.

Pavlinac PB, Hawes SE, Gottlieb GS, Gaye A, N'Diaye CF, Critchlow CW, Sow PSalif, Feng Q, Kiviat NB. HIV shedding in the oral cavity: an assessment of HIV type, immunovirologic, demographic and oral factors. Sex Transm Infect. 2012  ;88(1):45-50.

Ramos HJ, Lanteri MC, Blahnik G, Negash A, Suthar MS, Brassil MM, Sodhi K, Treuting PM, Busch MP, Norris PJ, et al. IL-1? signaling promotes CNS-intrinsic immune control of West Nile virus infection. PLoS Pathog. 2012  ;8(11):e1003039.

Suthar MS, Brassil MM, Blahnik G, Gale M. Infectious clones of novel lineage 1 and lineage 2 West Nile virus strains WNV-TX02 and WNV-Madagascar. J Virol. 2012  ;86(14):7704-9.

Rudd PA, Wilson J, Gardner J, Larcher T, Babarit C, Le TT, Anraku I, Kumagai Y, Loo Y-M, Gale M, et al. Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. J Virol. 2012  ;86(18):9888-98.

Bedard KM, Wang ML, Proll SC, Loo Y-M, Katze MG, Gale M, Iadonato SP. Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses. J Virol. 2012  ;86(13):7334-44.

Malur M, Gale M, Krug RM. LGP2 downregulates interferon production during infection with seasonal human influenza A viruses that activate interferon regulatory factor 3. J Virol. 2012  ;86(19):10733-8.

Liu HMinyi, Loo Y-M, Horner SM, Zornetzer GA, Katze MG, Gale M. The mitochondrial targeting chaperone 14-3-3? regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. Cell Host Microbe. 2012  ;11(5):528-37.

Buckner FS, Bahia MTerezinha, Suryadevara PK, White KL, Shackleford DM, Chennamaneni NKumar, Hulverson MA, Laydbak JU, Chatelain E, Scandale I, et al. Pharmacological characterization, structural studies, and in vivo activities of anti-Chagas disease lead compounds derived from tipifarnib. Antimicrob Agents Chemother. 2012  ;56(9):4914-21.

Suthar MS, Ramos HJ, Brassil MM, Netland J, Chappell CP, Blahnik G, McMillan A, Diamond MS, Clark EA, Bevan MJ, et al. The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness. Immunity. 2012  ;37(2):235-48.

Polyak SJ, Morishima C, Scott JD, Gastaminza P, Cox A, de Araújo EStanislau, Higgs MR, Loo Y-M, Golden-Mason L, Lindenbach BD, et al. A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology. 2012  ;142(1):e1-5.

Tanino Y, Chang MY, Wang X, Gill SE, Skerrett S, McGuire JK, Sato S, Nikaido T, Kojima T, Munakata M, et al. Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide. Am J Respir Cell Mol Biol. 2012  ;47(2):196-202.

Smith RA, Raugi DN, Pan C, Coyne M, Hernandez A, Church B, Parker K, Mullins JI, Sow PSalif, Gottlieb GS. Three main mutational pathways in HIV-2 lead to high-level raltegravir and elvitegravir resistance: implications for emerging HIV-2 treatment regimens. PLoS One. 2012  ;7(9):e45372.

Lee H-C, Headley MB, Loo Y-M, Berlin A, Gale M, Debley JS, Lukacs NW, Ziegler SF. Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection. J Allergy Clin Immunol. 2012  ;130(5):1187-1196.e5.

Heitzinger K, Sow PS, Badiane NMDia, Gottlieb GS, N'Doye I, Toure M, Kiviat NB, Hawes SE. Trends of HIV-1, HIV-2 and dual infection in women attending outpatient clinics in Senegal, 1990-2009. Int J STD AIDS. 2012  ;23(10):710-6.

Grimes M, Sahi SK, B Godornes C, Tantalo LC, Roberts N, Bostick D, Marra CM, Lukehart SA. Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington. Sex Transm Dis. 2012  ;39(12):954-8.

Shibata S, Gillespie RJ, Ranade RM, Koh CY, Kim JE, Laydbak JU, Zucker FH, Hol WGJ, Verlinde CLMJ, Buckner FS, et al. Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization. J Med Chem. 2012  ;55(14):6342-51.

Schnell G, Loo Y-M, Marcotrigiano J, Gale M. Uridine composition of the poly-U/UC tract of HCV RNA defines non-self recognition by RIG-I. PLoS Pathog. 2012  ;8(8):e1002839.

Chang M, Gottlieb GS, Dragavon JA, Cherne SL, Kenney DL, Hawes SE, Smith RA, Kiviat NB, Sow PSalif, Coombs RW. Validation for clinical use of a novel HIV-2 plasma RNA viral load assay using the Abbott m2000 platform. J Clin Virol. 2012  ;55(2):128-33.

Herbeck JT, Müller V, Maust BS, Ledergerber B, Torti C, Di Giambenedetto S, Gras L, Günthard HF, Jacobson LP, Mullins JI, et al. Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission. AIDS. 2012  ;26(2):193-205.

Doehle BP, Chang K, Rustagi A, McNevin J, McElrath JM, Gale M. Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism. J Virol. 2012  ;86(16):8367-74.

Doehle BP, Chang K, Fleming L, McNevin J, Hladik F, McElrath JM, Gale M. Vpu-deficient HIV strains stimulate innate immune signaling responses in target cells. J Virol. 2012  ;86(16):8499-506.

Zheng NN, McElrath JM, Sow PSalif, Mesher A, Hawes SE, Stern J, Gottlieb GS, De Rosa SC, Kiviat NB. Association between peripheral ?? T-cell profile and disease progression in individuals infected with HIV-1 or HIV-2 in West Africa. J Acquir Immune Defic Syndr. 2011  ;57(2):92-100.

Lazear HM, Pinto AK, Vogt MR, Gale M, Diamond MS. Beta interferon controls West Nile virus infection and pathogenesis in mice. J Virol. 2011  ;85(14):7186-94.

Abendroth J, Sankaran B, Edwards TE, Gardberg AS, Dieterich S, Bhandari J, Napuli AJ, Van Voorhis WC, Staker BL, Myler PJ, et al. BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative ?-lactamase-like protein' from Brucella melitensis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1106-12.

Luke JM, Simon GG, Söderholm J, Errett JS, J August T, Gale M, Hodgson CP, Williams JA. Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine. J Virol. 2011  ;85(3):1370-83.

Merritt EA, Arakaki TL, Gillespie R, Napuli AJ, Kim JE, Buckner FS, Van Voorhis WC, Verlinde CLMJ, Fan E, Zucker F, et al. Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase. Mol Biochem Parasitol. 2011  ;177(1):20-8.

Ramabu SS, Schneider DA, Brayton KA, Ueti MW, Graça T, Futse JE, Noh SM, Baszler TV, Palmer GH. Expression of Anaplasma marginale ankyrin repeat-containing proteins during infection of the mammalian host and tick vector. Infect Immun. 2011  ;79(7):2847-55.

Harman AN, Lai J, Turville S, Samarajiwa S, Gray L, Marsden V, Mercier SK, Mercier S, Jones K, Nasr N, et al. HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production. Blood. 2011  ;118(2):298-308.

Gottlieb GS, Smith RA, Badiane NMery Dia, Ba S, Hawes SE, Toure M, Starling AK, Traore F, Sall F, Cherne SL, et al. HIV-2 integrase variation in integrase inhibitor-naïve adults in Senegal, West Africa. PLoS One. 2011  ;6(7):e22204.

Crowther GJ, Napuli AJ, Gilligan JH, Gagaring K, Borboa R, Francek C, Chen Z, Dagostino EF, Stockmyer JB, Wang Y, et al. Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. Mol Biochem Parasitol. 2011  ;175(1):21-9.

Loo Y-M, Gale M. Immune signaling by RIG-I-like receptors. Immunity. 2011  ;34(5):680-92.

Quakkelaar ED, Redeker A, Haddad EK, Harari A, McCaughey SM, Duhen T, Filali-Mouhim A, Goulet J-P, Loof NM, Ossendorp F, et al. Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One. 2011  ;6(2):e16819.

Perwitasari O, Cho H, Diamond MS, Gale M. Inhibitor of ?B kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection. J Biol Chem. 2011  ;286(52):44412-23.

Nwaka S, Besson D, Ramirez B, Maes L, Matheeussen A, Bickle Q, Mansour NR, Yousif F, Townson S, Gokool S, et al. Integrated dataset of screening hits against multiple neglected disease pathogens. PLoS Negl Trop Dis. 2011  ;5(12):e1412.

Brien JD, Daffis S, Lazear HM, Cho H, Suthar MS, Gale M, Diamond MS. Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection. PLoS Pathog. 2011  ;7(9):e1002230.

Gujjar R, El Mazouni F, White KL, White J, Creason S, Shackleford DM, Deng X, Charman WN, Bathurst I, Burrows J, et al. Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice. J Med Chem. 2011  ;54(11):3935-49.

Iyer JG, Afanasiev OK, McClurkan C, Paulson K, Nagase K, Jing L, Marshak JO, Dong L, Carter J, Lai I, et al. Merkel cell polyomavirus-specific CD8? and CD4? T-cell responses identified in Merkel cell carcinomas and blood. Clin Cancer Res. 2011  ;17(21):6671-80.

Horner SM, Liu HMinyi, Park HSoo, Briley J, Gale M. Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc Natl Acad Sci U S A. 2011  ;108(35):14590-5.

Giordano D, Li C, Suthar MS, Draves KE, Ma DY, Gale M, Clark EA. Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses. J Leukoc Biol. 2011  ;89(3):443-55.

Baggstrom MQ, Qi Y, Koczywas M, Argiris A, Johnson EA, Millward MJ, Murphy SC, Erlichman C, Rudin CM, Govindan R. A phase II study of AT-101 (Gossypol) in chemotherapy-sensitive recurrent extensive-stage small cell lung cancer. J Thorac Oncol. 2011  ;6(10):1757-60.

Smith RA, Raugi DN, Kiviat NB, Hawes SE, Mullins JI, Sow PS, Gottlieb GS. Phenotypic susceptibility of HIV-2 to raltegravir: integrase mutations Q148R and N155H confer raltegravir resistance. AIDS. 2011  ;25(18):2235-41.

Ramos HJ, Gale M. RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity. Curr Opin Virol. 2011  ;1(3):167-76.

Ireton RC, Gale M. RIG-I like receptors in antiviral immunity and therapeutic applications. Viruses. 2011  ;3(6):906-19.

Shibata S, Gillespie RJ, Kelley AM, Napuli AJ, Zhang Z, Kovzun KV, Pefley RM, Lam J, Zucker FH, Van Voorhis WC, et al. Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice. Antimicrob Agents Chemother. 2011  ;55(5):1982-9.

Jiang F, Ramanathan A, Miller MT, Tang G-Q, Gale M, Patel SS, Marcotrigiano J. Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature. 2011  ;479(7373):423-7.

Edwards TE, Abramov AB, Smith ER, Baydo RO, Leonard JT, Leibly DJ, Thompkins KB, Clifton MC, Gardberg AS, Staker BL, et al. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. BMC Struct Biol. 2011  ;11:39.

Phan I, Subramanian S, Olsen C, Edwards TE, Guo W, Zhang Y, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1123-8.

Zhang Y, Edwards TE, Begley DW, Abramov A, Thompkins KB, Ferrell M, Guo WJ, Phan I, Olsen C, Napuli A, et al. Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1100-5.

Clifton MC, Abendroth J, Edwards TE, Leibly DJ, Gillespie AK, Ferrell M, Dieterich SH, Exley I, Staker BL, Myler PJ, et al. Structure of the cystathionine ?-synthase MetB from Mycobacterium ulcerans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1154-8.

Nguyen TN, Abendroth J, Leibly DJ, Le KP, Guo W, Kelley A, Stewart L, Myler PJ, Van Voorhis WC. Structure of triosephosphate isomerase from Cryptosporidium parvum. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011  ;67(Pt 9):1095-9.

Mercado-Curiel RF, Palmer GH, Guerrero FD, Brayton KA. Temporal characterisation of the organ-specific Rhipicephalus microplus transcriptional response to Anaplasma marginale infection. Int J Parasitol. 2011  ;41(8):851-60.

Paulson KG, Iyer JG, Tegeder AR, Thibodeau R, Schelter J, Koba S, Schrama D, Simonson WT, Lemos BD, Byrd DR, et al. Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J Clin Oncol. 2011  ;29(12):1539-46.

Mwangi DM, Honda Y, Graham SP, Pelle R, Taracha ELN, Gachanja J, Nyanjui JK, Bray J, Palmer GH, Brown WC, et al. Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-? responses but not CTL responses. Vet Immunol Immunopathol. 2011  ;140(3-4):244-51.

Liu HMinyi, Gale M. ZAPS electrifies RIG-I signaling. Nat Immunol. 2011  ;12(1):11-2.

Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin T-Y, Schneller S, Zust R, Dong H, et al. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature. 2010  ;468(7322):452-6.

Giacani L, Molini BJ, Kim EY, B Godornes C, B Leader T, Tantalo LC, Centurion-Lara A, Lukehart SA. Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis. J Immunol. 2010  ;184(7):3822-9.

Guiguemde AW, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, et al. Chemical genetics of Plasmodium falciparum. Nature. 2010  ;465(7296):311-5.

Gessain A, Rose TM, Lavergne A, Lacoste V. Comment on Mugisha et al. J Med Primatol 2010; 39: 71-76. J Med Primatol. 2010  ;39(5):363-4; author reply 365-6.

Giacani L, Jeffrey BM, Molini BJ, Le HT, Lukehart SA, Centurion-Lara A, Rockey DD. Complete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain. J Bacteriol. 2010  ;192(10):2645-6.

Larson ET, Mudeppa DG, Gillespie RJ, Mueller N, Napuli AJ, Arif JA, Ross J, Arakaki TL, Lauricella A, Detitta G, et al. The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase. J Mol Biol. 2010  ;396(5):1244-59.

Merritt EA, Arakaki TL, Gillespie RJ, Larson ET, Kelley A, Mueller N, Napuli AJ, Kim J, Zhang L, Verlinde CLMJ, et al. Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs. J Mol Biol. 2010  ;397(2):481-94.

Smith LS, Gharib SA, Frevert CW, Martin TR. Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice. Am J Respir Cell Mol Biol. 2010  ;43(4):475-86.

Marra CM, Sahi SK, Tantalo LC, Godornes C, Reid T, Behets F, Rompalo A, Klausner JD, Yin YPing, Mulcahy F, et al. Enhanced molecular typing of treponema pallidum: geographical distribution of strain types and association with neurosyphilis. J Infect Dis. 2010  ;202(9):1380-8.

Yuan HJ, Jain M, Snow KK, Gale M, Lee WM. Evolution of hepatitis C virus NS5A region in breakthrough patients during pegylated interferon and ribavirin therapy*. J Viral Hepat. 2010  ;17(3):208-16.

Curlin ME, Zioni R, Hawes SE, Liu Y, Deng W, Gottlieb GS, Zhu T, Mullins JI. HIV-1 envelope subregion length variation during disease progression. PLoS Pathog. 2010  ;6(12):e1001228.

Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, et al. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010  ;107(35):15589-94.

Tenover FC, Novak-Weekley S, Woods CW, Peterson LR, Davis T, Schreckenberger P, Fang FC, Dascal A, Gerding DN, Nomura JH, et al. Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches. J Clin Microbiol. 2010  ;48(10):3719-24.

Szretter KJ, Daffis S, Patel J, Suthar MS, Klein RS, Gale M, Diamond MS. The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system. J Virol. 2010  ;84(23):12125-38.

Suthar MS, Ma DY, Thomas S, Lund JM, Zhang N, Daffis S, Rudensky AY, Bevan MJ, Clark EA, Kaja M-K, et al. IPS-1 is essential for the control of West Nile virus infection and immunity. PLoS Pathog. 2010  ;6(2):e1000757.

Gilchrist M, Henderson WR, Morotti A, Johnson CD, Nachman A, Schmitz F, Smith KD, Aderem A. A key role for ATF3 in regulating mast cell survival and mediator release. Blood. 2010  ;115(23):4734-41.

Tanino Y, Coombe DR, Gill SE, Kett WC, Kajikawa O, Proudfoot AEI, Wells TNC, Parks WC, Wight TN, Martin TR, et al. Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol. 2010  ;184(5):2677-85.

Gottlieb GS, Smith RA, Sow PSalif. Long-term nonprogressive disease among individuals with untreated HIV infection. JAMA. 2010  ;304(16):1784; author reply 1785-6.

Chun CD, W Liles C, Frevert CW, Glenny RW, Altemeier WA. Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study. BMC Pulm Med. 2010  ;10:57.

Limou S, Coulonges C, Herbeck JT, van Manen D, An P, Le Clerc S, Delaneau O, Diop G, Taing L, Montes M, et al. Multiple-cohort genetic association study reveals CXCR6 as a new chemokine receptor involved in long-term nonprogression to AIDS. J Infect Dis. 2010  ;202(6):908-15.

Herbeck JT, Gottlieb GS, Winkler CA, Nelson GW, An P, Maust BS, Wong KG, Troyer JL, Goedert JJ, Kessing BD, et al. Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS. J Infect Dis. 2010  ;201(4):618-26.

Gill S, Wight TN, Frevert CW. Proteoglycans: key regulators of pulmonary inflammation and the innate immune response to lung infection. Anat Rec (Hoboken). 2010  ;293(6):968-81.

Wilkins C, Gale M. Recognition of viruses by cytoplasmic sensors. Curr Opin Immunol. 2010  ;22(1):41-7.

Malathi K, Saito T, Crochet N, Barton DJ, Gale M, Silverman RH. RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP. RNA. 2010  ;16(11):2108-19.

Kraus JM, Tatipaka HBabu, McGuffin SA, Chennamaneni NKumar, Karimi M, Arif J, Verlinde CLMJ, Buckner FS, Gelb MH. Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery. J Med Chem. 2010  ;53(10):3887-98.

Edwards TE, Phan I, Abendroth J, Dieterich SH, Masoudi A, Guo W, Hewitt SN, Kelley A, Leibly D, Brittnacher MJ, et al. Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. PLoS One. 2010  ;5(9).

Fletcher S, Keaney EP, Cummings CG, Blaskovich MA, Hast MA, Glenn MP, Chang S-Y, Bucher CJ, Floyd RJ, Katt WP, et al. Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents. J Med Chem. 2010  ;53(19):6867-88.

Smith RA, Gottlieb GS, A Miller D. Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors. Retrovirology. 2010  ;7:70.

Yager JE, Ford ES, Boas ZP, Haseley LA, Cookson BT, Sengupta DJ, Fang FC, Gottlieb GS. Ureaplasma urealyticum continuous ambulatory peritoneal dialysis-associated peritonitis diagnosed by 16S rRNA gene PCR. J Clin Microbiol. 2010  ;48(11):4310-2.

Watson-Jones D, Wald A, Celum C, Lingappa J, Weiss HA, Changalucha J, Baisley K, Tanton C, Hayes RJ, Marshak JO, et al. Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials. J Clin Microbiol. 2010  ;48(10):3496-503.

Crowther GJ, He P, Rodenbough PP, Thomas AP, Kovzun KV, Leibly DJ, Bhandari J, Castaneda LJ, Hol WGJ, Gelb MH, et al. Use of thermal melt curves to assess the quality of enzyme preparations. Anal Biochem. 2010  ;399(2):268-75.

Tait ED, Jordan KA, Dupont CD, Harris TH, Gregg B, Wilson EH, Pepper M, Dzierszinski F, Roos DS, Hunter CA. Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells. J Immunol. 2010  ;185(3):1502-12.

Wilcox MH, Planche T, Fang FC, Gilligan P. What is the current role of algorithmic approaches for diagnosis of Clostridium difficile infection?. J Clin Microbiol. 2010  ;48(12):4347-53.

Lanford RE, Evans MJ, Lohmann V, Lindenbach B, Gale M, Rehermann B, Chang K-M, Lemon SM. The accelerating pace of HCV research: a summary of the 15th International Symposium on Hepatitis C Virus And Related Viruses. Gastroenterology. 2009  ;136(1):9-16.

Ayi K, W Liles C, Gros P, Kain KC. Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. J Infect Dis. 2009  ;200(8):1289-99.

Torres-Santos ECaio, Sampaio-Santos MIsabel, Buckner FS, Yokoyama K, Gelb M, Urbina JA, Rossi-Bergmann B. Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone. J Antimicrob Chemother. 2009  ;63(3):469-72.

Smith RA, Anderson DJ, Pyrak CL, Preston BD, Gottlieb GS. Antiretroviral drug resistance in HIV-2: three amino acid changes are sufficient for classwide nucleoside analogue resistance. J Infect Dis. 2009  ;199(9):1323-6.

Owen DM, Huang H, Ye J, Gale M. Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor. Virology. 2009  ;394(1):99-108.

Conroy A, Serghides L, Finney C, Owino SO, Kumar S, D Gowda C, W Liles C, Moore JM, Kain KC. C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. PLoS One. 2009  ;4(3):e4953.

Gulati RK, Kwan-Gett T, Hampson NB, Baer A, Shusterman D, Shandro JR, Duchin JS. Carbon monoxide epidemic among immigrant populations: King County, Washington, 2006. Am J Public Health. 2009  ;99(9):1687-92.

Dark MJ, Herndon DR, Kappmeyer LS, Gonzales MP, Nordeen E, Palmer GH, Knowles DP, Brayton KA. Conservation in the face of diversity: multistrain analysis of an intracellular bacterium. BMC Genomics. 2009  ;10:16.

Gottlieb GS, Badiane NMery Dia, Hawes SE, Fortes L, Toure M, Ndour CT, Starling AK, Traore F, Sall F, Wong KG, et al. Emergence of multiclass drug-resistance in HIV-2 in antiretroviral-treated individuals in Senegal: implications for HIV-2 treatment in resouce-limited West Africa. Clin Infect Dis. 2009  ;48(4):476-83.

Suthar MS, Gale M, Owen DM. Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses. Cell Microbiol. 2009  ;11(6):880-8.

Herbeck JT, Gottlieb GS, Wong K, Detels R, Phair JP, Rinaldo CR, Jacobson LP, Margolick JB, Mullins JI. Fidelity of SNP array genotyping using Epstein Barr virus-transformed B-lymphocyte cell lines: implications for genome-wide association studies. PLoS One. 2009  ;4(9):e6915.

Owen DM, Gale M. Fighting the flu with inflammasome signaling. Immunity. 2009  ;30(4):476-8.

Quartley E, Alexandrov A, Mikucki M, Buckner FS, Hol WG, Detitta GT, Phizicky EM, Grayhack EJ. Heterologous expression of L. major proteins in S. cerevisiae: a test of solubility, purity, and gene recoding. J Struct Funct Genomics. 2009  ;10(3):233-47.

Mandal S, Maharjan M, Ganguly S, Chatterjee M, Singh S, Buckner FS, Madhubala R. High-throughput screening of amastigotes of Leishmania donovani clinical isolates against drugs using a colorimetric beta-lactamase assay. Indian J Exp Biol. 2009  ;47(6):475-9.

Campbell MS, Gottlieb GS, Hawes SE, Nickle DC, Wong KG, Deng W, Lampinen TM, Kiviat NB, Mullins JI. HIV-1 superinfection in the antiretroviral therapy era: are seroconcordant sexual partners at risk?. PLoS One. 2009  ;4(5):e5690.

Doehle BP, Hladik F, McNevin JP, McElrath JM, Gale M. Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells. J Virol. 2009  ;83(20):10395-405.

Gujjar R, Marwaha A, El Mazouni F, White J, White KL, Creason S, Shackleford DM, Baldwin J, Charman WN, Buckner FS, et al. Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice. J Med Chem. 2009  ;52(7):1864-72.

Galletti MFBM, Ueti MW, Knowles DP, Brayton KA, Palmer GH. Independence of Anaplasma marginale strains with high and low transmission efficiencies in the tick vector following simultaneous acquisition by feeding on a superinfected mammalian reservoir host. Infect Immun. 2009  ;77(4):1459-64.

Daffis S, Suthar MS, Szretter KJ, Gale M, Diamond MS. Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7. PLoS Pathog. 2009  ;5(10):e1000607.

Horner SM, Gale M. Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. J Interferon Cytokine Res. 2009  ;29(9):489-98.

Chennamaneni NKumar, Arif J, Buckner FS, Gelb MH. Isoquinoline-based analogs of the cancer drug clinical candidate tipifarnib as anti-Trypanosoma cruzi agents. Bioorg Med Chem Lett. 2009  ;19(23):6582-4.

DeWitte-Orr SJ, Mehta DR, Collins SE, Suthar MS, Gale M, Mossman KL. Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN. J Immunol. 2009  ;183(10):6545-53.

Daffis S, Suthar MS, Gale M, Diamond MS. Measure and countermeasure: type I IFN (IFN-alpha/beta) antiviral response against West Nile virus. J Innate Immun. 2009  ;1(5):435-45.

Gharib SA, W Liles C, Klaff LS, Altemeier WA. Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics. 2009  ;37(3):239-48.

A Bruce G, Bakke AM, Gravett CA, DeMaster LK, Bielefeldt-Ohmann H, Burnside KL, Rose TM. The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques. Virol J. 2009  ;6:205.

Jain MK, Yuan H-J, Adams-Huet B, Reeck A, Shelton J, Attar N, Zhang S, Neumann AU, Carney DS, Gale M, et al. Pegylated interferon and ribavirin promote early evolution of nonstructural 5A protein in individuals with hepatitis C who demonstrate a response to treatment. J Infect Dis. 2009  ;200(6):866-76.

Kraus JM, Verlinde CLMJ, Karimi M, Lepesheva GI, Gelb MH, Buckner FS. Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem. 2009  ;52(6):1639-47.

Serghides L, Patel SN, Ayi K, Lu Z, D Gowda C, W Liles C, Kain KC. Rosiglitazone modulates the innate immune response to Plasmodium falciparum infection and improves outcome in experimental cerebral malaria. J Infect Dis. 2009  ;199(10):1536-45.

Helmers AJ, D Gowda C, Kain KC, W Liles C. Statins fail to improve outcome in experimental cerebral malaria and potentiate Toll-like receptor-mediated cytokine production by murine macrophages. Am J Trop Med Hyg. 2009  ;81(4):631-7.

Roxby AC, Gottlieb GS, Limaye AP. Strongyloidiasis in transplant patients. Clin Infect Dis. 2009  ;49(9):1411-23.

Hast MA, Fletcher S, Cummings CG, Pusateri EE, Blaskovich MA, Rivas K, Gelb MH, Van Voorhis WC, Sebti SM, Hamilton AD, et al. Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem Biol. 2009  ;16(2):181-92.

Suryadevara PK, Olepu S, Lockman JW, Ohkanda J, Karimi M, Verlinde CLMJ, Kraus JM, Schoepe J, Van Voorhis WC, Hamilton AD, et al. Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease. J Med Chem. 2009  ;52(12):3703-15.

Bollyky PL, Bice JB, Sweet IR, Falk BA, Gebe JA, Clark AE, Gersuk VH, Aderem A, Hawn TR, Nepom GT. The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury. PLoS One. 2009  ;4(4):e5063.

Giacani L, Godornes C, Puray-Chavez M, Guerra-Giraldez C, Tompa M, Lukehart SA, Centurion-Lara A. TP0262 is a modulator of promoter activity of tpr Subfamily II genes of Treponema pallidum ssp. pallidum. Mol Microbiol. 2009  ;72(5):1087-99.

Gale M, Sen GC. Viral evasion of the interferon system. J Interferon Cytokine Res. 2009  ;29(9):475-6.

Milgrom P, Ly KA, Tut OK, Mancl L, Roberts MC, Briand K, Gancio MJane. Xylitol pediatric topical oral syrup to prevent dental caries: a double-blind randomized clinical trial of efficacy. Arch Pediatr Adolesc Med. 2009  ;163(7):601-7.

Olepu S, Suryadevara PK, Rivas K, Yokoyama K, Verlinde CLMJ, Chakrabarti D, Van Voorhis WC, Gelb MH. 2-Oxo-tetrahydro-1,8-naphthyridines as selective inhibitors of malarial protein farnesyltransferase and as anti-malarials. Bioorg Med Chem Lett. 2008  ;18(2):494-7.

Bulbule VJ, Rivas K, Verlinde CLMJ, Van Voorhis WC, Gelb MH. 2-Oxotetrahydroquinoline-based antimalarials with high potency and metabolic stability. J Med Chem. 2008  ;51(3):384-7.

Gilchrist M, Henderson WR, Clark AE, Simmons RM, Ye X, Smith KD, Aderem A. Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation. J Exp Med. 2008  ;205(10):2349-57.

Gelati M, Aplin AC, Fogel E, Smith KD, Nicosia RF. The angiogenic response of the aorta to injury and inflammatory cytokines requires macrophages. J Immunol. 2008  ;181(8):5711-9.

Erickson AK, Seiwert S, Gale M. Antiviral potency analysis and functional comparison of consensus interferon, interferon-alpha2a and pegylated interferon-alpha2b against hepatitis C virus infection. Antivir Ther. 2008  ;13(7):851-62.

Davis AM, Hagan KA, Matthews LA, Bajwa G, Gill MA, Gale M, J Farrar D. Blockade of virus infection by human CD4+ T cells via a cytokine relay network. J Immunol. 2008  ;180(10):6923-32.

Patel SN, Berghout J, Lovegrove FE, Ayi K, Conroy A, Serghides L, Min-Oo G, D Gowda C, J Sarma V, Rittirsch D, et al. C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med. 2008  ;205(5):1133-43.

Gottlieb GS, Eholié S-P, Nkengasong JN, Jallow S, Rowland-Jones S, Whittle HC, Sow PSalif. A call for randomized controlled trials of antiretroviral therapy for HIV-2 infection in West Africa. AIDS. 2008  ;22(16):2069-72; discussion 2073-4.

Arakaki TL, Buckner FS, Gillespie RJ, Malmquist NA, Phillips MA, Kalyuzhniy O, Luft JR, Detitta GT, Verlinde CLMJ, Van Voorhis WC, et al. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies. Mol Microbiol. 2008  ;68(1):37-50.

Gottlieb GS, Hawes SE, Kiviat NB, Sow PSalif. Differences in proviral DNA load between HIV-1-infected and HIV-2-infected patients. AIDS. 2008  ;22(11):1379-80.

Saito T, Gale M. Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity. J Exp Med. 2008  ;205(7):1523-7.

Loo Y-M, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, et al. Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol. 2008  ;82(1):335-45.

Taylor JA, Rietberg K, Greenfield L, Bibus D, Yasuda K, Marcuse EK, Duchin JS. Effectiveness of a physician peer educator in improving the quality of immunization services for young children in primary care practices. Vaccine. 2008  ;26(33):4256-61.

Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M. Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1. J Virol. 2008  ;82(2):609-16.

Mair C, Hawes SE, Agne HD, Sow PS, N'Doye I, Manhart LE, Fu PL, Gottlieb GS, Kiviat NB. Factors associated with CD4 lymphocyte counts in HIV-negative Senegalese individuals. Clin Exp Immunol. 2008  ;151(3):432-40.

Ojo KK, Gillespie RJ, Riechers AJ, Napuli AJ, Verlinde CLMJ, Buckner FS, Gelb MH, Domostoj MM, Wells SJ, Scheer A, et al. Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy. Antimicrob Agents Chemother. 2008  ;52(10):3710-7.

Gottlieb GS, Hawes SE, Wong KG, Raugi DN, Agne HD, Critchlow CW, Kiviat NB, Sow PSalif. HIV type 2 protease, reverse transcriptase, and envelope viral variation in the PBMC and genital tract of ARV-naive women in Senegal. AIDS Res Hum Retroviruses. 2008  ;24(6):857-64.

Gottlieb GS, Heath L, Nickle DC, Wong KG, Leach SE, Jacobs B, Gezahegne S, Wout AB van 't, Jacobson LP, Margolick JB, et al. HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study. J Infect Dis. 2008  ;197(7):1011-5.

Smith RA, Gottlieb GS, Anderson DJ, Pyrak CL, Preston BD. Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro. Antimicrob Agents Chemother. 2008  ;52(1):329-32.

Caws M, Thwaites G, Dunstan S, Hawn TR, Lan NThi Ngoc, Thuong NThuy Thuon, Stepniewska K, Huyen MNguyet Thu, Bang NDuc, Loc THuu, et al. The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog. 2008  ;4(3):e1000034.

Saito T, Owen DM, Jiang F, Marcotrigiano J, Gale M. Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA. Nature. 2008  ;454(7203):523-7.

Stinear TP, Seemann T, Harrison PF, Jenkin GA, Davies JK, Johnson PDR, Abdellah Z, Arrowsmith C, Chillingworth T, Churcher C, et al. Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. Genome Res. 2008  ;18(5):729-41.

H Garrigues J, Rubinchikova YE, C Dipersio M, Rose TM. Integrin alphaVbeta3 Binds to the RGD motif of glycoprotein B of Kaposi's sarcoma-associated herpesvirus and functions as an RGD-dependent entry receptor. J Virol. 2008  ;82(3):1570-80.

Daffis S, Samuel MA, Suthar MS, Keller BC, Gale M, Diamond MS. Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection. J Virol. 2008  ;82(17):8465-75.

Lau DT-Y, Fish PMar, Sinha M, Owen DM, Lemon SM, Gale M. Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. Hepatology. 2008  ;47(3):799-809.

Herbeck JT, Gottlieb GS, Li X, Hu Z, Detels R, Phair J, Rinaldo C, Jacobson LP, Margolick JB, Mullins JI. Lack of evidence for changing virulence of HIV-1 in North America. PLoS One. 2008  ;3(2):e1525.

Hawes SE, Sow PSalif, Stern JE, Critchlow CW, Gottlieb GS, Kiviat NB. Lower levels of HIV-2 than HIV-1 in the female genital tract: correlates and longitudinal assessment of viral shedding. AIDS. 2008  ;22(18):2517-25.

Chung RT, Gale M, Polyak SJ, Lemon SM, T Liang J, Hoofnagle JH. Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop. Hepatology. 2008  ;47(1):306-20.

Takahasi K, Yoneyama M, Nishihori T, Hirai R, Kumeta H, Narita R, Gale M, Inagaki F, Fujita T. Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell. 2008  ;29(4):428-40.

Lovegrove FE, Gharib SA, Peña-Castillo L, Patel SN, Ruzinski JT, Hughes TR, W Liles C, Kain KC. Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog. 2008  ;4(5):e1000068.

Cattamanchi A, Posavad CM, Wald A, Baine Y, Moses J, Higgins TJ, Ginsberg R, Ciccarelli R, Corey L, Koelle DM. Phase I study of a herpes simplex virus type 2 (HSV-2) DNA vaccine administered to healthy, HSV-2-seronegative adults by a needle-free injection system. Clin Vaccine Immunol. 2008  ;15(11):1638-43.

Chapman LE, Sullivent EE, Grohskopf LA, Beltrami EM, Perz JF, Kretsinger K, Panlilio AL, Thompson ND, Ehrenberg RL, Gensheimer KF, et al. Postexposure interventions to prevent infection with HBV, HCV, or HIV, and tetanus in people wounded during bombings and other mass casualty events--United States, 2008: recommendations of the Centers for Disease Control and Prevention and Disaster Medici. Disaster Med Public Health Prep. 2008  ;2(3):150-65.

Fletcher S, Cummings CG, Rivas K, Katt WP, Hornéy C, Buckner FS, Chakrabarti D, Sebti SM, Gelb MH, Van Voorhis WC, et al. Potent, Plasmodium-selective farnesyltransferase inhibitors that arrest the growth of malaria parasites: structure-activity relationships of ethylenediamine-analogue scaffolds and homology model validation. J Med Chem. 2008  ;51(17):5176-97.

Yokoyama K, Gillespie JR, Van Voorhis WC, Buckner FS, Gelb MH. Protein geranylgeranyltransferase-I of Trypanosoma cruzi. Mol Biochem Parasitol. 2008  ;157(1):32-43.

Chapman LE, Sullivent EE, Grohskopf LA, Beltrami EM, Perz JF, Kretsinger K, Panlilio AL, Thompson ND, Ehrenberg RL, Gensheimer KF, et al. Recommendations for postexposure interventions to prevent infection with hepatitis B virus, hepatitis C virus, or human immunodeficiency virus, and tetanus in persons wounded during bombings and other mass-casualty events--United States, 2008: recommendat. MMWR Recomm Rep. 2008  ;57(RR-6):1-21; quiz CE1-4.

Saito T, Gale M. Regulation of innate immunity against hepatitis C virus infection. Hepatol Res. 2008  ;38(2):115-22.

Erickson AK, Gale M. Regulation of interferon production and innate antiviral immunity through translational control of IRF-7. Cell Res. 2008  ;18(4):433-5.

Saito T, Gale M. [RIG-I mediated hepatic innate immune signaling that controls HCV infection]. Uirusu. 2008  ;58(2):105-15.

Otto CM, Markstaller K, Kajikawa O, Karmrodt J, Syring RS, Pfeiffer B, Good VP, Frevert CW, Baumgardner JE. Spatial and temporal heterogeneity of ventilator-associated lung injury after surfactant depletion. J Appl Physiol (1985). 2008  ;104(5):1485-94.

Fan E, Baker D, Fields S, Gelb MH, Buckner FS, Van Voorhis WC, Phizicky E, Dumont M, Mehlin C, Grayhack E, et al. Structural genomics of pathogenic protozoa: an overview. Methods Mol Biol. 2008  ;426:497-513.

Banas MC, Banas B, Hudkins KL, Wietecha TA, Iyoda M, Bock E, Hauser P, Pippin JW, Shankland SJ, Smith KD, et al. TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol. 2008  ;19(4):704-13.

Daffis S, Samuel MA, Suthar MS, Gale M, Diamond MS. Toll-like receptor 3 has a protective role against West Nile virus infection. J Virol. 2008  ;82(21):10349-58.

Yeganeh M, Henneke P, Rezaei N, Ehl S, Thiel D, Matamoros N, Pietrogrande C, Espanol T, Litzman J, Franco JL, et al. Toll-like receptor stimulation induces higher TNF-alpha secretion in peripheral blood mononuclear cells from patients with hyper IgE syndrome. Int Arch Allergy Immunol. 2008  ;146(3):190-4.

Buskin SE, Ellis GM, Pepper GG, Frenkel LM, Pergam SA, Gottlieb GS, Horwitch C, Olliffe JF, Johnson K, Shalit P, et al. Transmission cluster of multiclass highly drug-resistant HIV-1 among 9 men who have sex with men in Seattle/King County, WA, 2005-2007. J Acquir Immune Defic Syndr. 2008  ;49(2):205-11.

Loo Y-M, Gale M. Unveiling viral enablers. Nat Biotechnol. 2008  ;26(10):1093-4.

Goff WL, Johnson WC, Molloy JB, Jorgensen WK, Waldron SJ, Figueroa JV, Matthee O, D Adams S, McGuire TC, Pino I, et al. Validation of a competitive enzyme-linked immunosorbent assay for detection of Babesia bigemina antibodies in cattle. Clin Vaccine Immunol. 2008  ;15(9):1316-21.

Leader BT, Godornes C, VanVoorhis WC, Lukehart SA. CD4+ lymphocytes and gamma interferon predominate in local immune responses in early experimental syphilis. Infect Immun. 2007  ;75(6):3021-6.

Daffis S, Samuel MA, Keller BC, Gale M, Diamond MS. Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms. PLoS Pathog. 2007  ;3(7):e106.

Gillespie JR, Yokoyama K, Lu K, Eastman RT, Bollinger JG, Van Voorhis WC, Gelb MH, Buckner FS. C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins. Mol Biochem Parasitol. 2007  ;153(2):115-24.

Van Voorhis WC, Rivas KL, Bendale P, Nallan L, Hornéy C, Barrett LK, Bauer KD, Smart BP, Ankala S, Hucke O, et al. Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. Antimicrob Agents Chemother. 2007  ;51(10):3659-71.

Lovegrove FE, Gharib SA, Patel SN, Hawkes CA, Kain KC, W Liles C. Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria. Am J Pathol. 2007  ;171(6):1894-903.

Johnson CL, Owen DM, Gale M. Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense. J Biol Chem. 2007  ;282(14):10792-803.

Tan DHS, Bunce PE, W Liles C, Gold WL. Gemcitabine-related "pseudocellulitis": report of 2 cases and review of the literature. Clin Infect Dis. 2007  ;45(5):e72-6.

Huang H, Sun F, Owen DM, Li W, Chen Y, Gale M, Ye J. Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc Natl Acad Sci U S A. 2007  ;104(14):5848-53.

Gottlieb GS, Nickle DC, Jensen MA, Wong KG, Kaslow RA, Shepherd JC, Margolick JB, Mullins JI. HIV type 1 superinfection with a dual-tropic virus and rapid progression to AIDS: a case report. Clin Infect Dis. 2007  ;45(4):501-9.

Rolland M, Brander C, Nickle DC, Herbeck JT, Gottlieb GS, Campbell MS, Maust BS, Mullins JI. HIV-1 over time: fitness loss or robustness gain?. Nat Rev Microbiol. 2007  ;5(9):C1.

Loo Y-M, Gale M. Influenza: fatal immunity and the 1918 virus. Nature. 2007  ;445(7125):267-8.

Mibayashi M, Martinez-Sobrido L, Loo Y-M, Cárdenas WB, Gale M, García-Sastre A. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J Virol. 2007  ;81(2):514-24.

Keller BC, Johnson CL, Erickson AKaup, Gale M. Innate immune evasion by hepatitis C virus and West Nile virus. Cytokine Growth Factor Rev. 2007  ;18(5-6):535-44.

Gottlieb GS, Hawes SE, Nickle DC, Herbeck JT, Kiviat NB, Mullins JI, Sow PSalif. Presenting plasma HIV RNA level and rate of CD4 T-cell decline. JAMA. 2007  ;297(8):805; author reply 806-7.

Saito T, Gale M. Principles of intracellular viral recognition. Curr Opin Immunol. 2007  ;19(1):17-23.

Godornes C, Leader BTroy, Molini BJ, Centurion-Lara A, Lukehart SA. Quantitation of rabbit cytokine mRNA by real-time RT-PCR. Cytokine. 2007  ;38(1):1-7.

Giacani L, Molini B, Godornes C, Barrett L, Van Voorhis W, Centurion-Lara A, Lukehart SA. Quantitative analysis of tpr gene expression in Treponema pallidum isolates: Differences among isolates and correlation with T-cell responsiveness in experimental syphilis. Infect Immun. 2007  ;75(1):104-12.

Wagoner J, Austin M, Green J, Imaizumi T, Casola A, Brasier A, Khabar KSA, Wakita T, Gale M, Polyak SJ. Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. J Virol. 2007  ;81(1):309-18.

Saito T, Hirai R, Loo Y-M, Owen D, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M. Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci U S A. 2007  ;104(2):582-7.

Eastman RT, White J, Hucke O, Yokoyama K, Verlinde CLMJ, Hast MA, Beese LS, Gelb MH, Rathod PK, Van Voorhis WC. Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. Mol Biochem Parasitol. 2007  ;152(1):66-71.

Zheng NN, McElrath JM, Sow P-S, Hawes SE, Diallo-Agne H, Stern JE, Li F, Mesher AL, Robinson AD, Gottlieb GS, et al. Role of human immunodeficiency virus (HIV)-specific T-cell immunity in control of dual HIV-1 and HIV-2 infection. J Virol. 2007  ;81(17):9061-71.

Gale M. The role of innate immunity in chronic hepatitis C viral infection. Gastroenterol Hepatol (N Y). 2007  ;3(9):683-4.

Bendale P, Olepu S, Suryadevara PK, Bulbule V, Rivas K, Nallan L, Smart B, Yokoyama K, Ankala S, Pendyala PR, et al. Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials. J Med Chem. 2007  ;50(19):4585-605.

Malathi K, Dong B, Gale M, Silverman RH. Small self-RNA generated by RNase L amplifies antiviral innate immunity. Nature. 2007  ;448(7155):816-9.

Cohen AL, Bhatnagar J, Reagan S, Zane SB, D'Angeli MA, Fischer M, Killgore G, Kwan-Gett TSheng, Blossom DB, Shieh W-J, et al. Toxic shock associated with Clostridium sordellii and Clostridium perfringens after medical and spontaneous abortion. Obstet Gynecol. 2007  ;110(5):1027-33.

Loo YM, Gale M. Viral regulation and evasion of the host response. Curr Top Microbiol Immunol. 2007  ;316:295-313.

Marra CM, Colina AP, Godornes C, Tantalo LC, Puray M, Centurion-Lara A, Lukehart SA. Antibiotic selection may contribute to increases in macrolide-resistant Treponema pallidum. J Infect Dis. 2006  ;194(12):1771-3.

Mitchell SJ, Engelman J, Kent CK, Lukehart SA, Godornes C, Klausner JD. Azithromycin-resistant syphilis infection: San Francisco, California, 2000-2004. Clin Infect Dis. 2006  ;42(3):337-45.

Johnson CL, Gale M. CARD games between virus and host get a new player. Trends Immunol. 2006  ;27(1):1-4.

Montoya PJ, Lukehart SA, Brentlinger PE, Blanco AJ, Floriano F, Sairosse J, Gloyd S. Comparison of the diagnostic accuracy of a rapid immunochromatographic test and the rapid plasma reagin test for antenatal syphilis screening in Mozambique. Bull World Health Organ. 2006  ;84(2):97-104.

Gharib SA, W Liles C, Matute-Bello G, Glenny RW, Martin TR, Altemeier WA. Computational identification of key biological modules and transcription factors in acute lung injury. Am J Respir Crit Care Med. 2006  ;173(6):653-8.

Robien MA, Bosch J, Buckner FS, Van Voorhis WCE, Worthey EA, Myler P, Mehlin C, Boni EE, Kalyuzhniy O, Anderson L, et al. Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site. Proteins. 2006  ;62(3):570-7.

Blanco M, Gutiérrez-Martin CB, Rodríguez-Ferri EF, Roberts MC, Navas J. Distribution of tetracycline resistance genes in Actinobacillus pleuropneumoniae isolates from Spain. Antimicrob Agents Chemother. 2006  ;50(2):702-8.

Hosken N, McGowan P, Meier A, Koelle DM, Sleath P, Wagener F, Elliott M, Grabstein K, Posavad C, Corey L. Diversity of the CD8+ T-cell response to herpes simplex virus type 2 proteins among persons with genital herpes. J Virol. 2006  ;80(11):5509-15.

Cárdenas WB, Loo Y-M, Gale M, Hartman AL, Kimberlin CR, Martinez-Sobrido L, Saphire EOllmann, Basler CF. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. J Virol. 2006  ;80(11):5168-78.

Philipp-Staheli J, Marquardt T, Thouless ME, A Bruce G, Grant RF, Tsai C-C, Rose TM. Genetic variability of the envelope gene of Type D simian retrovirus-2 (SRV-2) subtypes associated with SAIDS-related retroperitoneal fibromatosis in different macaque species. Virol J. 2006  ;3:11.

Chang A, Peutz-Kootstra CJ, Kowalewska J, Logar CM, Gitomer JJ, Davis CL, Shankland SJ, Alpers CE, Smith KD. Giant cell tubulitis with tubular basement membrane immune deposits: a report of two cases after cardiac valve replacement surgery. Clin J Am Soc Nephrol. 2006  ;1(5):920-4.

Mehlin C, Boni E, Buckner FS, Engel L, Feist T, Gelb MH, Haji L, Kim D, Liu C, Mueller N, et al. Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes. Mol Biochem Parasitol. 2006  ;148(2):144-60.

Herbeck JT, Nickle DC, Learn GH, Gottlieb GS, Curlin ME, Heath L, Mullins JI. Human immunodeficiency virus type 1 env evolves toward ancestral states upon transmission to a new host. J Virol. 2006  ;80(4):1637-44.

Gottlieb GS, Hawes SE, Agne HD, Stern JE, Critchlow CW, Kiviat NB, Sow PSalif. Lower levels of HIV RNA in semen in HIV-2 compared with HIV-1 infection: implications for differences in transmission. AIDS. 2006  ;20(6):895-900.

Dhanireddy S, Altemeier WA, Matute-Bello G, D O'Mahony S, Glenny RW, Martin TR, W Liles C. Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia. Lab Invest. 2006  ;86(8):790-9.

Centurion-Lara A, Molini BJ, Godornes C, Sun E, Hevner K, Van Voorhis WC, Lukehart SA. Molecular differentiation of Treponema pallidum subspecies. J Clin Microbiol. 2006  ;44(9):3377-80.

Gray RR, Mulligan CJ, Molini BJ, Sun ES, Giacani L, Godornes C, Kitchen A, Lukehart SA, Centurion-Lara A. Molecular evolution of the tprC, D, I, K, G, and J genes in the pathogenic genus Treponema. Mol Biol Evol. 2006  ;23(11):2220-33.

Samuel MA, Whitby K, Keller BC, Marri A, Barchet W, Williams BRG, Silverman RH, Gale M, Diamond MS. PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons. J Virol. 2006  ;80(14):7009-19.

Chien Y, Kim S, Bumeister R, Loo Y-M, Kwon SWon, Johnson CL, Balakireva MG, Romeo Y, Kopelovich L, Gale M, et al. RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell. 2006  ;127(1):157-70.

Liu H, Carrington M, Wang C, Holte S, Lee J, Greene B, Hladik F, Koelle DM, Wald A, Kurosawa K, et al. Repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule: effects on HIV-1 susceptibility. J Infect Dis. 2006  ;193(5):698-702.

Keller BC, Fredericksen BL, Samuel MA, Mock RE, Mason PW, Diamond MS, Gale M. Resistance to alpha/beta interferon is a determinant of West Nile virus replication fitness and virulence. J Virol. 2006  ;80(19):9424-34.

Glenn MP, Chang S-Y, Hornéy C, Rivas K, Yokoyama K, Pusateri EE, Fletcher S, Cummings CG, Buckner FS, Pendyala PR, et al. Structurally simple, potent, Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites. J Med Chem. 2006  ;49(19):5710-27.

Eastman RT, Buckner FS, Yokoyama K, Gelb MH, Van Voorhis WC. Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation. J Lipid Res. 2006  ;47(2):233-40.

Gelb MH, Brunsveld L, Hrycyna CA, Michaelis S, Tamanoi F, Van Voorhis WC, Waldmann H. Therapeutic intervention based on protein prenylation and associated modifications. Nat Chem Biol. 2006  ;2(10):518-28.

LaFond RE, Centurion-Lara A, Godornes C, Van Voorhis WC, Lukehart SA. TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain. Infect Immun. 2006  ;74(3):1896-906.

Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, Detitta G, et al. Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J Med Chem. 2006  ;49(20):5939-46.

Loo Y-M, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, D Carney S, Wang T, Ishida H, Yoneyama M, et al. Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proc Natl Acad Sci U S A. 2006  ;103(15):6001-6.

Fredericksen BL, Gale M. West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling. J Virol. 2006  ;80(6):2913-23.

Matute-Bello G, W Liles C, Frevert CW, Dhanireddy S, Ballman K, Wong V, Green RR, Song HYeong, Witcher DR, Jakubowski JA, et al. Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen. J Infect Dis. 2005  ;191(4):596-606.

Onufryk C, Crouch M-L, Fang FC, Gross CA. Characterization of six lipoproteins in the sigmaE regulon. J Bacteriol. 2005  ;187(13):4552-61.

Foy E, Li K, Sumpter R, Loo Y-M, Johnson CL, Wang C, Fish PMar, Yoneyama M, Fujita T, Lemon SM, et al. Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci U S A. 2005  ;102(8):2986-91.

Navarre WWiley, Halsey TA, Walthers D, Frye J, McClelland M, Potter JL, Kenney LJ, Gunn JS, Fang FC, Libby SJ. Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ. Mol Microbiol. 2005  ;56(2):492-508.

Li K, Chen Z, Kato N, Gale M, Lemon SM. Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem. 2005  ;280(17):16739-47.

Hübel K, Rodger E, J Gaviria M, Price TH, Dale DC, W Liles C. Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor. Transfusion. 2005  ;45(12):1876-89.

Gale M, Foy EM. Evasion of intracellular host defence by hepatitis C virus. Nature. 2005  ;436(7053):939-45.

Roach JC, Glusman G, Rowen L, Kaur A, Purcell MK, Smith KD, Hood LE, Aderem A. The evolution of vertebrate Toll-like receptors. Proc Natl Acad Sci U S A. 2005  ;102(27):9577-82.

González JC, Kwok WW, Wald A, McClurkan CL, Huang J, Koelle DM. Expression of cutaneous lymphocyte-associated antigen and E-selectin ligand by circulating human memory CD4+ T lymphocytes specific for herpes simplex virus type 2. J Infect Dis. 2005  ;191(2):243-54.

Xiang J, Martinez-Smith C, Gale M, Chang Q, Labrecque DR, Schmidt WN, Stapleton JT. GB virus type C NS5A sequence polymorphisms: association with interferon susceptibility and inhibition of PKR-mediated eIF2alpha phosphorylation. J Interferon Cytokine Res. 2005  ;25(5):261-70.

Kajikawa O, Frevert CW, Lin S-M, Goodman RB, Mongovin SM, Wong V, Ballman K, Daubeuf B, Elson G, Martin TR. Gene expression of Toll-like receptor-2, Toll-like receptor-4, and MD2 is differentially regulated in rabbits with Escherichia coli pneumonia. Gene. 2005  ;344:193-202.

Beard CB, Fox MR, Lawrence GG, Guarner J, Hanzlick RL, Huang L, del Rio C, Rimland D, Duchin JS, Colley DG. Genetic differences in Pneumocystis isolates recovered from immunocompetent infants and from adults with AIDS: Epidemiological Implications. J Infect Dis. 2005  ;192(10):1815-8.

Koelle DM, Gonzalez JC, Johnson AS. Homing in on the cellular immune response to HSV-2 in humans. Am J Reprod Immunol. 2005  ;53(4):172-81.

Wang C, Gale M, Keller BC, Huang H, Brown MS, Goldstein JL, Ye J. Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. Mol Cell. 2005  ;18(4):425-34.

Li K, Foy E, Ferreon JC, Nakamura M, Ferreon ACM, Ikeda M, Ray SC, Gale M, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A. 2005  ;102(8):2992-7.

Bielefeldt-Ohmann H, Barouch DH, Bakke AM, Bruce AG, Durning M, Grant R, Letvin NL, Ryan JT, Schmidt A, Thouless ME, et al. Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta). Vet Pathol. 2005  ;42(3):391-6.

Altemeier WA, Matute-Bello G, Gharib SA, Glenny RW, Martin TR, W Liles C. Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol. 2005  ;175(5):3369-76.

Gottlieb GS, Nickle DC. Multidrug-resistant, dual-tropic HIV-1 and rapid progression. Lancet. 2005  ;365(9475):1923-4; author reply 1924.

Giménez-Barcons M, Wang C, Chen M, Sánchez-Tapias J-M, Sáiz J-C, Gale M. The oncogenic potential of hepatitis C virus NS5A sequence variants is associated with PKR regulation. J Interferon Cytokine Res. 2005  ;25(3):152-64.

Lack NA, Green B, Dale DC, Calandra GB, Lee H, MacFarland RT, Badel K, Liles WC, Bridger G. A pharmacokinetic-pharmacodynamic model for the mobilization of CD34+ hematopoietic progenitor cells by AMD3100. Clin Pharmacol Ther. 2005  ;77(5):427-36.

Limaye AP, Smith KD, Cook L, Groom DA, Hunt NC, Jerome KR, Boeckh M. Polyomavirus nephropathy in native kidneys of non-renal transplant recipients. Am J Transplant. 2005  ;5(3):614-20.

Koelle DM, Ghiasi H. Prospects for developing an effective vaccine against ocular herpes simplex virus infection. Curr Eye Res. 2005  ;30(11):929-42.

Buckner FS, Eastman RT, Yokoyama K, Gelb MH, Van Voorhis WC. Protein farnesyl transferase inhibitors for the treatment of malaria and African trypanosomiasis. Curr Opin Investig Drugs. 2005  ;6(8):791-7.

Hucke O, Gelb MH, Verlinde CLMJ, Buckner FS. The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease. J Med Chem. 2005  ;48(17):5415-8.

Nallan L, Bauer KD, Bendale P, Rivas K, Yokoyama K, Hornéy CP, Pendyala PR, Floyd D, Lombardo LJ, Williams DK, et al. Protein farnesyltransferase inhibitors exhibit potent antimalarial activity. J Med Chem. 2005  ;48(11):3704-13.

Broxmeyer HE, Orschell CM, D Clapp W, Hangoc G, Cooper S, P Plett A, W Liles C, Li X, Graham-Evans B, Campbell TB, et al. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med. 2005  ;201(8):1307-18.

Lee WM, Polson JE, D Carney S, Sahin B, Gale M. Reemergence of hepatitis C virus after 8.5 years in a patient with hypogammaglobulinemia: evidence for an occult viral reservoir. J Infect Dis. 2005  ;192(6):1088-92.

Sumpter R, Loo Y-M, Foy E, Li K, Yoneyama M, Fujita T, Lemon SM, Gale M. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol. 2005  ;79(5):2689-99.

Eastman RT, White J, Hucke O, Bauer K, Yokoyama K, Nallan L, Chakrabarti D, Verlinde CLMJ, Gelb MH, Rathod PK, et al. Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum. J Biol Chem. 2005  ;280(14):13554-9.

Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo Y-M, Gale M, Akira S, et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol. 2005  ;175(5):2851-8.

Hawn TR, Wu H, Grossman JM, Hahn BH, Tsao BP, Aderem A. A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2005  ;102(30):10593-7.

Glenn MP, Chang S-Y, Hucke O, Verlinde CLMJ, Rivas K, Hornéy C, Yokoyama K, Buckner FS, Pendyala PR, Chakrabarti D, et al. Structurally simple farnesyltransferase inhibitors arrest the growth of malaria parasites. Angew Chem Int Ed Engl. 2005  ;44(31):4903-6.

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Hankins EG, Gillespie JR, Aikenhead K, Buckner FS. Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors. Mol Biochem Parasitol. 2005  ;144(1):68-75.

Dhanireddy S, W Liles C, Gates GA. Vestibular toxic effects induced by once-daily aminoglycoside therapy. Arch Otolaryngol Head Neck Surg. 2005  ;131(1):46-8.

Sow PSalif, Hawes SE, Critchlow CW, McIntosh MW, Diop A, Diouf MB, Gottlieb GS, Starling AK, Coll-Seck AM, Kiviat NB. Characteristics and presenting complaints of outpatients with undiagnosed HIV infection: potential utility in selecting subjects for HIV testing. J Acquir Immune Defic Syndr. 2004  ;37(4):1520-8.

Zheng NN, Kiviat NB, Sow PS, Hawes SE, Wilson A, Diallo-Agne H, Critchlow CW, Gottlieb GS, Musey L, McElrath MJ. Comparison of human immunodeficiency virus (HIV)-specific T-cell responses in HIV-1- and HIV-2-infected individuals in Senegal. J Virol. 2004  ;78(24):13934-42.

Ohkanda J, Buckner FS, Lockman JW, Yokoyama K, Carrico D, Eastman R, de Luca-Fradley K, Davies W, Croft SL, Van Voorhis WC, et al. Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents. J Med Chem. 2004  ;47(2):432-45.

Brenciani A, Ojo KK, Monachetti A, Menzo S, Roberts MC, Varaldo PE, Giovanetti E. Distribution and molecular analysis of mef(A)-containing elements in tetracycline-susceptible and -resistant Streptococcus pyogenes clinical isolates with efflux-mediated erythromycin resistance. J Antimicrob Chemother. 2004  ;54(6):991-8.

Gottlieb GS, Nickle DC, Jensen MA, Wong KG, Grobler J, Li F, Liu S-L, Rademeyer C, Learn GH, Karim SSAbdool, et al. Dual HIV-1 infection associated with rapid disease progression. Lancet. 2004  ;363(9409):619-22.

Murphy SC, Gilroy D, Kerry JF, Buckley DJ, Kerry JP. Evaluation of surimi, fat and water content in a low/no added pork sausage formulation using response surface methodology. Meat Sci. 2004  ;66(3):689-701.

Halsey TA, Vazquez-Torres A, Gravdahl DJ, Fang FC, Libby SJ. The ferritin-like Dps protein is required for Salmonella enterica serovar Typhimurium oxidative stress resistance and virulence. Infect Immun. 2004  ;72(2):1155-8.

Centurion-Lara A, LaFond RE, Hevner K, Godornes C, Molini BJ, Van Voorhis WC, Lukehart SA. Gene conversion: a mechanism for generation of heterogeneity in the tprK gene of Treponema pallidum during infection. Mol Microbiol. 2004  ;52(6):1579-96.

Fredericksen BL, Smith M, Katze MG, Shi P-Y, Gale M. The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway. J Virol. 2004  ;78(14):7737-47.

Stich RW, Olah GA, Brayton KA, Brown WC, Fechheimer M, Green-Church K, Jittapalapong S, Kocan KM, McGuire TC, Rurangirwa FR, et al. Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection. Infect Immun. 2004  ;72(12):7257-64.

Carrico D, Ohkanda J, Kendrick H, Yokoyama K, Blaskovich MA, Bucher CJ, Buckner FS, Van Voorhis WC, Chakrabarti D, Croft SL, et al. In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. Bioorg Med Chem. 2004  ;12(24):6517-26.

Schapiro JM, Gupta R, Stefansson E, Fang FC, Limaye AP. Isolation of metronidazole-resistant Bacteroides fragilis carrying the nimA nitroreductase gene from a patient in Washington State. J Clin Microbiol. 2004  ;42(9):4127-9.

Lukehart SA, Godornes C, Molini BJ, Sonnett P, Hopkins S, Mulcahy F, Engelman J, Mitchell SJ, Rompalo AM, Marra CM, et al. Macrolide resistance in Treponema pallidum in the United States and Ireland. N Engl J Med. 2004  ;351(2):154-8.

Altemeier WA, Matute-Bello G, Frevert CW, Kawata Y, Kajikawa O, Martin TR, Glenny RW. Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin. Am J Physiol Lung Cell Mol Physiol. 2004  ;287(3):L533-42.

Curlin ME, Gottlieb GS, Hawes SE, Sow PSalif, Ndoye I, Critchlow CW, Kiviat NB, Mullins JI. No evidence for recombination between HIV type 1 and HIV type 2 within the envelope region in dually seropositive individuals from Senegal. AIDS Res Hum Retroviruses. 2004  ;20(9):958-63.

Gandhi M, Koelle DM, Ameli N, Bacchetti P, Greenspan JS, Navazesh M, Anastos K, Greenblatt RM. Prevalence of human herpesvirus-8 salivary shedding in HIV increases with CD4 count. J Dent Res. 2004  ;83(8):639-43.

Palmer GH, Knowles DP, Rodríguez J-L, Gnad DP, Hollis LC, Marston T, Brayton KA. Stochastic transmission of multiple genotypically distinct Anaplasma marginale strains in a herd with high prevalence of Anaplasma infection. J Clin Microbiol. 2004  ;42(11):5381-4.

Tan S-L, He Y, Huang Y, Gale M. Strategies for hepatitis C therapeutic intervention: now and next. Curr Opin Pharmacol. 2004  ;4(5):465-70.

Giacani L, Sun ES, Hevner K, Molini BJ, Van Voorhis WC, Lukehart SA, Centurion-Lara A. Tpr homologs in Treponema paraluiscuniculi Cuniculi A strain. Infect Immun. 2004  ;72(11):6561-76.

Sumpter R, Wang C, Foy E, Loo Y-M, Gale M. Viral evolution and interferon resistance of hepatitis C virus RNA replication in a cell culture model. J Virol. 2004  ;78(21):11591-604.

Wang C, Pflugheber J, Sumpter R, Sodora DL, Hui D, Sen GC, Gale M. Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication. J Virol. 2003  ;77(7):3898-912.

Frevert CW, Kinsella MG, Vathanaprida C, Goodman RB, Baskin DG, Proudfoot A, Wells TNC, Wight TN, Martin TR. Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue. Am J Respir Cell Mol Biol. 2003  ;28(4):464-72.

Liu C-Y, Takemasa A, W Liles C, Goodman RB, Jonas M, Rosen H, Chi E, Winn RK, Harlan JM, Chuang PI. Broad-spectrum caspase inhibition paradoxically augments cell death in TNF-alpha -stimulated neutrophils. Blood. 2003  ;101(1):295-304.

Buckner F, Yokoyama K, Lockman J, Aikenhead K, Ohkanda J, Sadilek M, Sebti S, Van Voorhis W, Hamilton A, Gelb MH. A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents. Proc Natl Acad Sci U S A. 2003  ;100(25):15149-53.

Nickle DC, Jensen MA, Gottlieb GS, Shriner D, Learn GH, Rodrigo AG, Mullins JI. Consensus and ancestral state HIV vaccines. Science. 2003  ;299(5612):1515-8; author reply 1515-8.

Ye J, Wang C, Sumpter R, Brown MS, Goldstein JL, Gale M. Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc Natl Acad Sci U S A. 2003  ;100(26):15865-70.

Gottlieb GS, Lesser CF, Holmes KK, Wald A. Disseminated sporotrichosis associated with treatment with immunosuppressants and tumor necrosis factor-alpha antagonists. Clin Infect Dis. 2003  ;37(6):838-40.

Lee JS, Frevert CW, Wurfel MM, Peiper SC, Wong VA, Ballman KK, Ruzinski JT, Rhim JS, Martin TR, Goodman RB. Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo. J Immunol. 2003  ;170(10):5244-51.

Gale M. Effector genes of interferon action against hepatitis C virus. Hepatology. 2003  ;37(5):975-8.

Lee JS, Frevert CW, Thorning DR, Segerer S, Alpers CE, Cartron J-P, Colin Y, Wong VA, Martin TR, Goodman RB. Enhanced expression of Duffy antigen in the lungs during suppurative pneumonia. J Histochem Cytochem. 2003  ;51(2):159-66.

Gottlieb GS, Sow PSalif, Hawes SE, Ndoye I, Coll-Seck AM, Curlin ME, Critchlow CW, Kiviat NB, Mullins JI. Molecular epidemiology of dual HIV-1/HIV-2 seropositive adults from Senegal, West Africa. AIDS Res Hum Retroviruses. 2003  ;19(7):575-84.

Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, et al. A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J Exp Med. 2003  ;198(5):679-91.

Hinshaw JC, Suh D-Y, Garnier P, Buckner FS, Eastman RT, Matsuda SPT, Joubert BM, Coppens I, Joiner KA, Merali S, et al. Oxidosqualene cyclase inhibitors as antimicrobial agents. J Med Chem. 2003  ;46(20):4240-3.

Giovanetti E, Brenciani A, Lupidi R, Roberts MC, Varaldo PE. Presence of the tet(O) gene in erythromycin- and tetracycline-resistant strains of Streptococcus pyogenes and linkage with either the mef(A) or the erm(A) gene. Antimicrob Agents Chemother. 2003  ;47(9):2844-9.

Gelb MH, Van Voorhis WC, Buckner FS, Yokoyama K, Eastman R, Carpenter EP, Panethymitaki C, Brown KA, Smith DF. Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics. Mol Biochem Parasitol. 2003  ;126(2):155-63.

Picard C, Puel A, Bonnet M, Ku C-L, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science. 2003  ;299(5615):2076-9.

Hermouet S, Sutton CA, Rose TM, Greenblatt RJ, Corre I, Garand R, Neves AM, Bataille R, Casey JW. Qualitative and quantitative analysis of human herpesviruses in chronic and acute B cell lymphocytic leukemia and in multiple myeloma. Leukemia. 2003  ;17(1):185-95.

He Y, Yan W, Coito C, Li Y, Gale M, Katze MG. The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins. J Gen Virol. 2003  ;84(Pt 3):535-43.

Foy E, Li K, Wang C, Sumpter R, Ikeda M, Lemon SM, Gale M. Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science. 2003  ;300(5622):1145-8.

LaFond RE, Centurion-Lara A, Godornes C, Rompalo AM, Van Voorhis WC, Lukehart SA. Sequence diversity of Treponema pallidum subsp. pallidum tprK in human syphilis lesions and rabbit-propagated isolates. J Bacteriol. 2003  ;185(21):6262-8.

Gottlieb GS, Wald A, Agoff N. Unusual appendicitis. Clin Infect Dis. 2003  ;37(10):1334, 1378-9.

Fredericksen B, Akkaraju GR, Foy E, Wang C, Pflugheber J, Chen ZJ, Gale M. Activation of the interferon-beta promoter during hepatitis C virus RNA replication. Viral Immunol. 2002  ;15(1):29-40.

Imanishi T, Han DK, Hofstra L, Hano T, Nishio I, W Liles C, Gown AM, Schwartz SM, Han DKM, Gorden AM. Apoptosis of vascular smooth muscle cells is induced by Fas ligand derived from monocytes/macrophage. Atherosclerosis. 2002  ;161(1):143-51.

Geisler WM, Harrington RD, Wallis CK, Harnisch JP, W Liles C. Broad spectrum of dermatologic manifestations caused by Mycobacterium haemophilum infection. Arch Dermatol. 2002  ;138(2):229-30.

Chung WO, Gabany J, G Persson R, Roberts MC. Distribution of erm(F) and tet(Q) genes in 4 oral bacterial species and genotypic variation between resistant and susceptible isolates. J Clin Periodontol. 2002  ;29(2):152-8.

Gottlieb GS, Sow PSalif, Hawes SE, Ndoye I, Redman M, Coll-Seck AM, Faye-Niang MA, Diop A, Kuypers JM, Critchlow CW, et al. Equal plasma viral loads predict a similar rate of CD4+ T cell decline in human immunodeficiency virus (HIV) type 1- and HIV-2-infected individuals from Senegal, West Africa. J Infect Dis. 2002  ;185(7):905-14.

Agersø Y, Jensen LBogø, Givskov M, Roberts MC. The identification of a tetracycline resistance gene tet(M), on a Tn916-like transposon, in the Bacillus cereus group. FEMS Microbiol Lett. 2002  ;214(2):251-6.

Clerici F, Gelmi ML, Yokoyama K, Pocar D, Van Voorhis WC, Buckner FS, Gelb MH. Isothiazole dioxides: synthesis and inhibition of Trypanosoma brucei protein farnesyltransferase. Bioorg Med Chem Lett. 2002  ;12(16):2217-20.

Lewis CW, Riedy CA, Grossman DC, Domoto PK, Roberts MC. Oral health of young Alaska Native children and their caregivers in Southwestern Alaska. Alaska Med. 2002  ;44(4):83-7.

Gale M, Blakely CM, Darveau A, Romano PR, Korth MJ, Katze MG. P52rIPK regulates the molecular cochaperone P58IPK to mediate control of the RNA-dependent protein kinase in response to cytoplasmic stress. Biochemistry. 2002  ;41(39):11878-87.

J Davis M, Clay H, Lewis JL, Ghori N, Herbomel P, Ramakrishnan L. Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. Immunity. 2002  ;17(6):693-702.

Pflugheber J, Fredericksen B, Sumpter R, Wang C, Ware F, Sodora DL, Gale M. Regulation of PKR and IRF-1 during hepatitis C virus RNA replication. Proc Natl Acad Sci U S A. 2002  ;99(7):4650-5.

Frevert CW, Goodman RB, Kinsella MG, Kajikawa O, Ballman K, Clark-Lewis I, Proudfoot AEI, Wells TNC, Martin TR. Tissue-specific mechanisms control the retention of IL-8 in lungs and skin. J Immunol. 2002  ;168(7):3550-6.

Katze MG, He Y, Gale M. Viruses and interferon: a fight for supremacy. Nat Rev Immunol. 2002  ;2(9):675-87.

Bressi JC, Verlinde CL, Aronov AM, Shaw ML, Shin SS, Nguyen LN, Suresh S, Buckner FS, Van Voorhis WC, Kuntz ID, et al. Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design. J Med Chem. 2001  ;44(13):2080-93.

Gottlieb GS, Limaye AP, Chen YC, Van Voorhis WC. Candida dubliniensis fungemia in a solid organ transplant patient: case report and review of the literature. Med Mycol. 2001  ;39(6):483-5.

Koelle DM, Chen HB, Gavin MA, Wald A, Kwok WW, Corey L. CD8 CTL from genital herpes simplex lesions: recognition of viral tegument and immediate early proteins and lysis of infected cutaneous cells. J Immunol. 2001  ;166(6):4049-58.

Dale DC, Liles WC, Garwicz D, Aprikyan AG. Clinical implications of mutations of neutrophil elastase in congenital and cyclic neutropenia. J Pediatr Hematol Oncol. 2001  ;23(4):208-10.

Greenblatt RM, Jacobson LP, Levine AM, Melnick S, Anastos K, Cohen M, DeHovitz J, Young MA, Burns D, Miotti P, et al. Human herpesvirus 8 infection and Kaposi's sarcoma among human immunodeficiency virus-infected and -uninfected women. J Infect Dis. 2001  ;183(7):1130-4.

Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 2001  ;410(6832):1099-103.

Manning-Cela R, Cortés A, González-Rey E, Van Voorhis WC, Swindle J, González A. LYT1 protein is required for efficient in vitro infection by Trypanosoma cruzi. Infect Immun. 2001  ;69(6):3916-23.

Gale M, Beard MR. Molecular clones of hepatitis C virus: applications to animal models. ILAR J. 2001  ;42(2):139-51.

Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, et al. New ways of initiating translation in eukaryotes. Mol Cell Biol. 2001  ;21(23):8238-46.

Buckner FS, Griffin JH, Wilson AJ, Van Voorhis WC. Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors. Antimicrob Agents Chemother. 2001  ;45(4):1210-5.

Kwok WW, Gebe JA, Liu A, Agar S, Ptacek N, Hammer J, Koelle DM, Nepom GT. Rapid epitope identification from complex class-II-restricted T-cell antigens. Trends Immunol. 2001  ;22(11):583-8.

Gottlieb GS, Mullins JI. Re: Follow-up study of intrahost HIV type 2 variability reveals discontinuous evolution of C2V3 sequences. AIDS Res Hum Retroviruses. 2001  ;17(16):1563-5, 1567.

Matute-Bello G, Frevert CW, Kajikawa O, Skerrett SJ, Goodman RB, Park DR, Martin TR. Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infection. Am J Respir Crit Care Med. 2001  ;163(1):234-43.

Nepomuceno-Silva JL, Yokoyama K, de Mello LD, Mendonca SM, Paixão JC, Baron R, Faye JC, Buckner FS, Van Voorhis WC, Gelb MH, et al. TcRho1, a farnesylated Rho family homologue from Trypanosoma cruzi: cloning, trans-splicing, and prenylation studies. J Biol Chem. 2001  ;276(32):29711-8.

Novak EJ, Liu AW, Gebe JA, Falk BA, Nepom GT, Koelle DM, Kwok WW. Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens. J Immunol. 2001  ;166(11):6665-70.

Bressi JC, Choe J, Hough MT, Buckner FS, Van Voorhis WC, Verlinde CL, Hol WG, Gelb MH. Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine. J Med Chem. 2000  ;43(22):4135-50.

Shoda LK, Palmer GH, Florin-Christensen J, Florin-Christensen M, Godson DL, Brown WC. Babesia bovis-stimulated macrophages express interleukin-1beta, interleukin-12, tumor necrosis factor alpha, and nitric oxide and inhibit parasite replication in vitro. Infect Immun. 2000  ;68(9):5139-45.

Buckner FS, Yokoyama K, Nguyen L, Grewal A, Erdjument-Bromage H, Tempst P, Strickland CL, Xiao L, Van Voorhis WC, Gelb MH. Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei. J Biol Chem. 2000  ;275(29):21870-6.

Frevert CW, Matute-Bello G, Skerrett SJ, Goodman RB, Kajikawa O, Sittipunt C, Martin TR. Effect of CD14 blockade in rabbits with Escherichia coli pneumonia and sepsis. J Immunol. 2000  ;164(10):5439-45.

Kwok WW, Liu AW, Novak EJ, Gebe JA, Ettinger RA, Nepom GT, Reymond SN, Koelle DM. HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: direct detection of immunodominant antigen-responsive cells. J Immunol. 2000  ;164(8):4244-9.

Liles WC, Dale DC, Price TH, Gaviria JM, Turner T, Saoud J, Frumkin LR. Inhibition of in vivo neutrophil transmigration by a novel humanized anti-CD11/CD18 monoclonal antibody. Cytokines Cell Mol Ther. 2000  ;6(3):121-6.

Engelfriet CP, Reesink HW, Klein HG, Murphy MF, Pamphilon D, Devereux S, Höcker P, Adkins D, Boyce N, Tobin S, et al. International forum: granulocyte transfusions. Vox Sang. 2000  ;79(1):59-66.

Cameron CE, Lukehart SA, Castro C, Molini B, Godornes C, Van Voorhis WC. Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp92. J Infect Dis. 2000  ;181(4):1401-13.

Gopal AK, Fowler VG, Shah M, Gesty-Palmer D, Marr KA, McClelland RS, Kong LK, Gottlieb GS, Lanclos K, Li J, et al. Prospective analysis of Staphylococcus aureus bacteremia in nonneutropenic adults with malignancy. J Clin Oncol. 2000  ;18(5):1110-5.

Gottlieb GS, Fowler VG, Kong LK, McClelland RS, Gopal AK, Marr KA, Li J, Sexton DJ, Glower D, Corey GR. Staphylococcus aureus bacteremia in the surgical patient: a prospective analysis of 73 postoperative patients who developed Staphylococcus aureus bacteremia at a tertiary care facility. J Am Coll Surg. 2000  ;190(1):50-7.

Koelle DM, Reymond SN, Chen H, Kwok WW, McClurkan C, Gyaltsong T, Petersdorf EW, Rotkis W, Talley AR, Harrison DA. Tegument-specific, virus-reactive CD4 T cells localize to the cornea in herpes simplex virus interstitial keratitis in humans. J Virol. 2000  ;74(23):10930-8.

Centurion-Lara A, Godornes C, Castro C, Van Voorhis WC, Lukehart SA. The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles. Infect Immun. 2000  ;68(2):824-31.

Gale M, Tan SL, Katze MG. Translational control of viral gene expression in eukaryotes. Microbiol Mol Biol Rev. 2000  ;64(2):239-80.

Gale M, Kwieciszewski B, Dossett M, Nakao H, Katze MG. Antiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinase. J Virol. 1999  ;73(8):6506-16.

Gaviria JM, van Burik JA, Dale DC, Root RK, Liles WC. Comparison of interferon-gamma, granulocyte colony-stimulating factor, and granulocyte-macrophage colony-stimulating factor for priming leukocyte-mediated hyphal damage of opportunistic fungal pathogens. J Infect Dis. 1999  ;179(4):1038-41.

Cummings CJ, Martin TR, Frevert CW, Quan JM, Wong VA, Mongovin SM, Hagen TR, Steinberg KP, Goodman RB. Expression and function of the chemokine receptors CXCR1 and CXCR2 in sepsis. J Immunol. 1999  ;162(4):2341-6.

Goldberg SV, Duchin JS, Shields T, Nolan CM. Four-month, four-drug preventive therapy for inactive pulmonary tuberculosis. Am J Respir Crit Care Med. 1999  ;160(2):508-12.

Fowler VG, Sanders LL, Kong LK, McClelland RS, Gottlieb GS, Li J, Ryan T, Sexton DJ, Roussakis G, Harrell LJ, et al. Infective endocarditis due to Staphylococcus aureus: 59 prospectively identified cases with follow-up. Clin Infect Dis. 1999  ;28(1):106-14.

Tang NM, Korth MJ, Gale M, Wambach M, Der SD, Bandyopadhyay SK, Williams BR, Katze MG. Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK). Mol Cell Biol. 1999  ;19(7):4757-65.

Gaviria JM, van Burik JA, Dale DC, Root RK, Liles WC. Modulation of neutrophil-mediated activity against the pseudohyphal form of Candida albicans by granulocyte colony-stimulating factor (G-CSF) administered in vivo. J Infect Dis. 1999  ;179(5):1301-4.

Fowler VG, Kong LK, Corey GR, Gottlieb GS, McClelland RS, Sexton DJ, Gesty-Palmer D, Harrell LJ. Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients. J Infect Dis. 1999  ;179(5):1157-61.

Aronov AM, Suresh S, Buckner FS, Van Voorhis WC, Verlinde CL, Opperdoes FR, Hol WG, Gelb MH. Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A. 1999  ;96(8):4273-8.

Fang FC, DeGroote MA, Foster JW, Bäumler AJ, Ochsner U, Testerman T, Bearson S, Giárd JC, Xu Y, Campbell G, et al. Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases. Proc Natl Acad Sci U S A. 1999  ;96(13):7502-7.

van Besien K, Sobocinski KA, Rowlings PA, Murphy SC, Armitage JO, Bishop MR, Chaekal OK, Gale RP, Klein JP, Lazarus HM, et al. Allogeneic bone marrow transplantation for low-grade lymphoma. Blood. 1998  ;92(5):1832-6.

Gale M, Blakely CM, Kwieciszewski B, Tan SL, Dossett M, Tang NM, Korth MJ, Polyak SJ, Gretch DR, Katze MG. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol Cell Biol. 1998  ;18(9):5208-18.

Yokoyama K, Trobridge P, Buckner FS, Scholten J, Stuart KD, Van Voorhis WC, Gelb MH. The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth. Mol Biochem Parasitol. 1998  ;94(1):87-97.

Hensel M, Shea JE, Waterman SR, Mundy R, Nikolaus T, Banks G, Vazquez-Torres A, Gleeson C, Fang FC, Holden DW. Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages. Mol Microbiol. 1998  ;30(1):163-74.

Gale M, Katze MG. Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase. Pharmacol Ther. 1998  ;78(1):29-46.

Yokoyama K, Trobridge P, Buckner FS, Van Voorhis WC, Stuart KD, Gelb MH. Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kda subunits as a new target for antiparasite therapeutics. J Biol Chem. 1998  ;273(41):26497-505.

Goodman RB, Strieter RM, Frevert CW, Cummings CJ, Tekamp-Olson P, Kunkel SL, Walz A, Martin TR. Quantitative comparison of C-X-C chemokines produced by endotoxin-stimulated human alveolar macrophages. Am J Physiol. 1998  ;275(1 Pt 1):L87-95.

Frevert CW, Wong VA, Goodman RB, Goodwin R, Martin TR. Rapid fluorescence-based measurement of neutrophil migration in vitro. J Immunol Methods. 1998  ;213(1):41-52.

Chandran B, Smith MS, Koelle DM, Corey L, Horvat R, Goldstein E. Reactivities of human sera with human herpesvirus-8-infected BCBL-1 cells and identification of HHV-8-specific proteins and glycoproteins and the encoding cDNAs. Virology. 1998  ;243(1):208-17.

Gale M, Blakely CM, Hopkins DA, Melville MW, Wambach M, Romano PR, Katze MG. Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK. Mol Cell Biol. 1998  ;18(2):859-71.

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Bisognano JD, Young B, Brown JM, Gill EA, Fang FC, Zisman LS. Diverse presentation of aberrant origin of the right subclavian artery: two case reports. Chest. 1997  ;112(6):1693-7.

Ruef BJ, Tuo W, Rodriguez SD, Roussel AJ, Chitko-McKown CG, Palmer GH, McElwain TF, Canals A, Zarlenga DS, Gasbarre LC, et al. Immunization with Babesia bigemina rhoptry-associated protein 1 induces a type 1 cytokine response. J Interferon Cytokine Res. 1997  ;17(1):45-54.

Kajikawa O, Johnson MC, Goodman RB, Frevert CW, Martin TR. A sensitive immunoassay to detect the alpha-chemokine GRO in rabbit blood and lung fluids. J Immunol Methods. 1997  ;205(2):135-43.

Buchmeier N, Bossie S, Chen CY, Fang FC, Guiney DG, Libby SJ. SlyA, a transcriptional regulator of Salmonella typhimurium, is required for resistance to oxidative stress and is expressed in the intracellular environment of macrophages. Infect Immun. 1997  ;65(9):3725-30.

Gale M, Katze MG. What happens inside lentivirus or influenza virus infected cells: insights into regulation of cellular and viral protein synthesis. Methods. 1997  ;11(4):383-401.

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Wyatt CR, Davis WC, Knowles DP, Goff WL, Palmer GH, McGuire TC. Effect on intraerythrocytic Anaplasma marginale of soluble factors from infected calf blood mononuclear cells. Infect Immun. 1996  ;64(11):4846-9.

Buchwald D, Collier AC, Lukehart SA, Kith P, Goldstein E, Hooton TM. Evaluation of cerebrospinal fluid in Southeast Asian refugees with reactive serologic tests for syphilis. West J Med. 1996  ;165(5):289-93.

Chen CY, Eckmann L, Libby SJ, Fang FC, Okamoto S, Kagnoff MF, Fierer J, Guiney DG. Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infect Immun. 1996  ;64(11):4739-43.

Fang FC, Chen CY, Guiney DG, Xu Y. Identification of sigma S-regulated genes in Salmonella typhimurium: complementary regulatory interactions between sigma S and cyclic AMP receptor protein. J Bacteriol. 1996  ;178(17):5112-20.

Gale M, Tan SL, Wambach M, Katze MG. Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation. Mol Cell Biol. 1996  ;16(8):4172-81.

Gottlieb GS, Fennewald MA. UV photoaffinity labeling of Tn3 transposase--DNA complexes: identification of DNA binding domains. Can J Microbiol. 1996  ;42(1):46-59.

Guiney DG, Fang FC, Krause M, Libby S, Buchmeier NA, Fierer J. Biology and clinical significance of virulence plasmids in Salmonella serovars. Clin Infect Dis. 1995  ;21 Suppl 2:S146-51.

Chen CY, Buchmeier NA, Libby S, Fang FC, Krause M, Guiney DG. Central regulatory role for the RpoS sigma factor in expression of Salmonella dublin plasmid virulence genes. J Bacteriol. 1995  ;177(18):5303-9.

Moolenaar RL, Dalton C, Lipman HB, Umland ET, Gallaher M, Duchin JS, Chapman L, Zaki SR, Ksiazek TG, Rollin PE. Clinical features that differentiate hantavirus pulmonary syndrome from three other acute respiratory illnesses. Clin Infect Dis. 1995  ;21(3):643-9.

Buchmeier NA, Libby SJ, Xu Y, Loewen PC, Switala J, Guiney DG, Fang FC. DNA repair is more important than catalase for Salmonella virulence in mice. J Clin Invest. 1995  ;95(3):1047-53.

De Groote MA, Granger D, Xu Y, Campbell G, Prince R, Fang FC. Genetic and redox determinants of nitric oxide cytotoxicity in a Salmonella typhimurium model. Proc Natl Acad Sci U S A. 1995  ;92(14):6399-403.

Guiney DG, Libby S, Fang FC, Krause M, Fierer J. Growth-phase regulation of plasmid virulence genes in Salmonella. Trends Microbiol. 1995  ;3(7):275-9.

Hines SA, Palmer GH, Jasmer DP, Goff WL, McElwain TF. Immunization of cattle with recombinant Babesia bovis merozoite surface antigen-1. Infect Immun. 1995  ;63(1):349-52.

Gersuk VH, Rose TM, Todaro GJ. Molecular cloning and chromosomal localization of a pseudogene related to the human acyl-CoA binding protein/diazepam binding inhibitor. Genomics. 1995  ;25(2):469-76.

Krause M, Fang FC, el-Gedaily A, Libby S, Guiney DG. Mutational analysis of SpvR binding to DNA in the regulation of the Salmonella plasmid virulence operon. Plasmid. 1995  ;34(1):37-47.

Challoner PB, Smith KT, Parker JD, MacLeod DL, Coulter SN, Rose TM, Schultz ER, Bennett JL, Garber RL, Chang M. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci U S A. 1995  ;92(16):7440-4.

Gale M, Carter V, Parsons M. Cell cycle-specific induction of an 89 kDa serine/threonine protein kinase activity in Trypanosoma brucei. J Cell Sci. 1994  ;107 ( Pt 7):1825-32.

Jones RL, Godinho KS, Palmer GH. Clinical observations on the use of oral amoxycillin/clavulanate in the treatment of gingivitis in dogs and cats and anal sacculitis in dogs. Br Vet J. 1994  ;150(4):385-8.

Libby SJ, Goebel W, Ludwig A, Buchmeier N, Bowe F, Fang FC, Guiney DG, Songer JG, Heffron F. A cytolysin encoded by Salmonella is required for survival within macrophages. Proc Natl Acad Sci U S A. 1994  ;91(2):489-93.

Eriks IS, Stiller D, Goff WL, Panton M, Parish SM, McElwain TF, Palmer GH. Molecular and biological characterization of a newly isolated Anaplasma marginale strain. J Vet Diagn Invest. 1994  ;6(4):435-41.

Rose TM, Weiford DM, Gunderson NL, Bruce AG. Oncostatin M (OSM) inhibits the differentiation of pluripotent embryonic stem cells in vitro. Cytokine. 1994  ;6(1):48-54.

Guiney DG, Fang FC, Krause M, Libby S. Plasmid-mediated virulence genes in non-typhoid Salmonella serovars. FEMS Microbiol Lett. 1994  ;124(1):1-9.

Das A, Gale M, Carter V, Parsons M. The protein phosphatase inhibitor okadaic acid induces defects in cytokinesis and organellar genome segregation in Trypanosoma brucei. J Cell Sci. 1994  ;107 ( Pt 12):3477-83.

Mittl RL, Schwab RJ, Duchin JS, Goin JE, Albeida SM, Miller WT. Radiographic resolution of community-acquired pneumonia. Am J Respir Crit Care Med. 1994  ;149(3 Pt 1):630-5.

Gordon SM, Eaton ME, George R, Larsen S, Lukehart SA, Kuypers J, Marra CM, Thompson S. The response of symptomatic neurosyphilis to high-dose intravenous penicillin G in patients with human immunodeficiency virus infection. N Engl J Med. 1994  ;331(22):1469-73.

O'Neal CR, Gabriel WM, Turk AK, Libby SJ, Fang FC, Spector MP. RpoS is necessary for both the positive and negative regulation of starvation survival genes during phosphate, carbon, and nitrogen starvation in Salmonella typhimurium. J Bacteriol. 1994  ;176(15):4610-6.

Gale M, Carter V, Parsons M. Translational control mediates the developmental regulation of the Trypanosoma brucei Nrk protein kinase. J Biol Chem. 1994  ;269(50):31659-65.

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Gale M, Parsons M. A Trypanosoma brucei gene family encoding protein kinases with catalytic domains structurally related to Nek1 and NIMA. Mol Biochem Parasitol. 1993  ;59(1):111-21.

Fang FC, McClelland M, Guiney DG, Jackson MM, Hartstein AI, Morthland VH, Davis CE, McPherson DC, Welsh J. Value of molecular epidemiologic analysis in a nosocomial methicillin-resistant Staphylococcus aureus outbreak. JAMA. 1993  ;270(11):1323-8.

Fang FC, Libby SJ, Buchmeier NA, Loewen PC, Switala J, Harwood J, Guiney DG. The alternative sigma factor katF (rpoS) regulates Salmonella virulence. Proc Natl Acad Sci U S A. 1992  ;89(24):11978-82.

Krause M, Fang FC, Guiney DG. Regulation of plasmid virulence gene expression in Salmonella dublin involves an unusual operon structure. J Bacteriol. 1992  ;174(13):4482-9.

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Murphy SC, Cranker K, Senyk GF, Barbano DM, Saeman AI, Galton DM. Influence of bovine mastitis on lipolysis ond proteolysis in milk. J Dairy Sci. 1989  ;72(3):620-6.

Isaacs RD, Hanke JH, Guzman-Verduzco LM, Newport G, Agabian N, Norgard MV, Lukehart SA, Radolf JD. Molecular cloning and DNA sequence analysis of the 37-kilodalton endoflagellar sheath protein gene of Treponema pallidum. Infect Immun. 1989  ;57(11):3403-11.

Greenblatt RM, Lukehart SA, Plummer FA, Quinn TC, Critchlow CW, Ashley RL, D'Costa LJ, Ndinya-Achola JO, Corey L, Ronald AR. Genital ulceration as a risk factor for human immunodeficiency virus infection. AIDS. 1988  ;2(1):47-50.

McElwain TF, Palmer GH, Goff WL, McGuire TC. Identification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera. Infect Immun. 1988  ;56(6):1658-60.

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Garmendia AE, Palmer GH, DeMartini JC, McGuire TC. Failure of passive immunoglobulin transfer: a major determinant of mortality in newborn alpacas (Lama pacos). Am J Vet Res. 1987  ;48(10):1472-6.

Buckner FS, Chen FN, Wade CE, Ganong WF. Centrally administered inhibitors of the generation and action of angiotensin II do not attenuate the increase in ACTH secretion produced by ether stress in rats. Neuroendocrinology. 1986  ;42(2):97-101.

Miller LM, Reed SM, Gallina AM, Palmer GH. Ataxia and weakness associated with fourth ventricle vascular anomalies in two horses. J Am Vet Med Assoc. 1985  ;186(6):601-3.

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